Patrick J. Maguire
University College Dublin
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Publication
Featured researches published by Patrick J. Maguire.
Journal of Perinatal Medicine | 2015
Maria Farren; Niamh Daly; Amy O'Higgins; Aoife McKeating; Patrick J. Maguire; Michael J. Turner
Abstract There is a strong epidemiological association between maternal obesity and gestational diabetes mellitus (GDM). Since the publication of the Hyperglycemia and Adverse Pregnancy Outcome (HAPO) study on women with mild hyperglycemia in 2008, new criteria have been introduced in maternity services internationally for the diagnosis of GDM. As a result, the diagnosis of GDM may be made in one-third of obese women (n=68). The aim of this review was to examine the interplay between maternal obesity and GDM in light of the HAPO study and the subsequent revised diagnostic criteria. Obesity and GDM are important obstetric risk factors because they both are potentially modifiable. However, the new international criteria for the diagnosis of GDM have serious resource implications for maternity services provided to the large number of women attending for care in developed countries. Further consideration needs to be given as to whether obese women with mild hyperglycemia need to be referred to a multidisciplinary team antenatally if they do not require insulin treatment.
Hypertension in Pregnancy | 2011
Jennifer Hogan; Patrick J. Maguire; Nadine Farah; Mairead Kennelly; Bernard Stuart; Michael J. Turner
Objective. The accurate measurement of blood pressure requires the use of a large cuff in subjects with a high mid-arm circumference (MAC). This prospective study examined the need for a large cuff during pregnancy and its correlation with maternal obesity. Methods. Maternal body mass index (BMI), fat mass, and MAC were measured. Results. Of 179 women studied, 15.6% were obese. With a BMI of level 1 obesity, 44% needed a large cuff and with a BMI of level 2 obesity 100% needed a large cuff. Conclusion. All women booking for antenatal care should have their MAC measured to avoid the overdiagnosis of pregnancy hypertension.
International Journal of Gynecology & Obstetrics | 2015
Patrick J. Maguire; Amy O'Higgins; Karen A. Power; Niamh Daly; Aoife McKeating; Michael J. Turner
To assess whether introduction of the Irish maternity early warning system (IMEWS) in 2013 has improved the recording of vital signs among women with proven maternal bacteremia.
Acta Obstetricia et Gynecologica Scandinavica | 2015
Aoife McKeating; Patrick J. Maguire; Niamh Daly; Maria Farren; Léan McMahon; Michael J. Turner
Maternal obesity has been identified as an important clinical priority in contemporary obstetrics. This study aimed to determine the incidence of maternal obesity in early pregnancy and track recent trends in body mass index (BMI) categories over 5 years 2009–2013.
International Journal of Gynecology & Obstetrics | 2016
Patrick J. Maguire; Karen A. Power; Andrew F. Downey; Amy O'Higgins; Sharon R. Sheehan; Michael J. Turner
To examine, in the setting of maternal bacteremia, the implications for the diagnosis of maternal sepsis of customizing the systemic inflammatory response syndrome (SIRS) criteria for physiologic changes of pregnancy.
Journal of Maternal-fetal & Neonatal Medicine | 2016
Aoife McKeating; Patrick J. Maguire; Maria Farren; Niamh Daly; Sharon R. Sheehan; Michael J. Turner
Abstract Objective: The objective of this study was to compare the clinical outcomes of unplanned pregnancies among severely obese women with those of planned pregnancies. Methods: This prospective cohort study included severely obese women (Body Mass Index [BMI] ≥40.0 kg/m2) who delivered a baby weighing ≥500 g over 5 years 2009–2013 in a large university hospital. Maternal weight and height were measured and BMI was calculated at the first prenatal visit. Results: Of the 650 women, the mean BMI was 43.8 kg/m2, mean age was 31.6 years, and 30.0% (n = 195) were nulliparous. Prenatal complications including gestational diabetes mellitus (GDM), hypertensive and thromboembolic disorders occurred in 56.6% (n = 368). Compared with planned pregnancies (58.2%, n = 378), those that were unplanned (41.8%, n = 272) were associated with increased prepregnancy risk factors including essential hypertension (4.0% versus 1.6%, p = 0.03) and depression (6.6% versus 3.2%, p = 0.03). Unplanned pregnancy was associated with a higher macrosomia rate (birthweight > 4.5 kg) compared with planned pregnancies (p = 0.03). This was not explained by a higher GDM rate in unplanned pregnancies. Compared with planned pregnancies, unplanned pregnancies were not associated with increased adverse fetomaternal outcomes. Conclusion: Despite increased prepregnancy risk factors, in severely obese women, unplanned pregnancies were not associated with increased prenatal complications or adverse pregnancy outcomes compared with planned pregnancies.
International Journal of Gynecology & Obstetrics | 2016
Patrick J. Maguire; Karen A. Power; Niamh Daly; Maria Farren; Aoife McKeating; Michael J. Turner
[1] Hindin M, Kishor S, Ansara DL. Intimate Partner Violence among Couples in 10 DHS Countries: Predictors and Health Outcomes. DHS Analytical Studies, 18; 2008. [2] Catallozzi M, Simon PJ, Davidson LL, Breitbart V, Rickert VI. Understanding control in adolescent and young adult relationships. Arch Pediatr Adolesc Med 2011;165(4): 313–9. [3] Guedes A, Bott S, Cuca Y. Integrating systematic screening for gender-based violence into sexual and reproductive health services: results of a baseline study by the International Planned Parenthood Federation, Western Hemisphere Region. Int J Gynecol Obstet 2002;78(Suppl 1):S57–63.
Journal of Maternal-fetal & Neonatal Medicine | 2015
Patrick J. Maguire; Karen A. Power; Harley R; Mhurchú Mn; Sheehan; Fanning Ra; Michael J. Turner
Abstract Objective: There is little information about whether the established non-pregnant adult venous lactate reference range is appropriate for pregnancy. This prospective observational study examined whether the non-pregnant adult reference range is appropriate during pregnancy. Methods: Women attending for routine prenatal appointments or elective cesarean delivery in a tertiary hospital were recruited. Clinical details were recorded and venous lactate concentration was measured using a point-of-care (POC) device. Results: Of the 246 women, 199 were 6–18 weeks’ gestation and 47 were 36–42 weeks’ gestation. Mean lactate concentration was within the non-pregnant reference range in early and late pregnancy (0.86 SD ± 0.46 mmol/L and 1.15 SD ± 0.40 mmol/L, respectively). The mean time between phlebotomy and result was 6.1 SD ± 1.7 min. There was no correlation between lactate levels and either maternal age or time interval from tourniquet placement to lactate measurement. In women of 6–18 weeks’ gestation positive bivariate relationships were found between lactate and BMI (p = 0.03, r = 0.158), earlier gestational age (p = 0.04, r= −0.145), and smoking (p = 0.01, r = 0.183), but these were not found in late pregnancy. Conclusions: The venous lactate reference range for the non-pregnant adult may be applied in pregnancy. Further studies should examine lactate dynamics in labor and postpartum.
European Journal of Obstetrics & Gynecology and Reproductive Biology | 2015
Patrick J. Maguire; Karen A. Power; Amy O’Higgins; Sabrina Jackson; Ruth Harley; Carel W. le Roux; Michael J. Turner
American Journal of Obstetrics and Gynecology | 2015
Patrick J. Maguire; Michael J. Turner