Patrizia Belfiore
University of Naples Federico II
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Featured researches published by Patrizia Belfiore.
Human Vaccines & Immunotherapeutics | 2014
G. Liguori; Antonino Parlato; Alessandro Sanduzzi Zamparelli; Patrizia Belfiore; F. Gallè; Valeria Di Onofrio; Carla Riganti; Bruno Zamparelli
Pneumococcal pneumonia has a high clinical burden in terms of morbidity, mortality and hospitalization rate, with heavy implications for worldwide health systems. In particular, higher incidence and mortality rates of community-acquired pneumonia (CAP) cases, with related costs, are registered among elderly. This study aimed to an economic evaluation about the immunization with PCV13 in the adult population in Campania region, South Italy. For this purpose we performed, considering a period of 5 y, a budget impact analysis (BIA) and a cost-effectiveness analysis which considered 2 scenarios of immunization compared with lack of immunization for 2 targeted cohorts: first, the high risk subjects aged 50–79 y, and second the high risk individuals aged 50–64 y, together with all those aged 65 y. Regarding the first group, the decrease of pneumonia could give savings equal to €29 005 660, while the immunization of the second cohort could allow savings equal to €10 006 017. The economic evaluation of pneumococcal vaccine for adult groups represents an essential instrument to support health policies. This study showed that both hypothesized immunization strategies could produce savings. Obtained results support the use of pneumococcal conjugate vaccine for adults. This strategy could represent a sustainable and savings-producer health policy.
Geriatrics & Gerontology International | 2016
F. Gallè; Valeria Di Onofrio; Vincenzo Romano Spica; Pio Russo Krauss; Patrizia Belfiore; Pasqualina Buono; G. Liguori
To evaluate the efficacy and feasibility of a physical activity promotion intervention in community‐dwelling older adults based on a free program of exercise adapted for older adults aged ≥60 years managed by trainees from the Movement Sciences degree course.
Infectious disorders drug targets | 2018
Alessandro Sanduzzi; Angelo Canora; Patrizia Belfiore; Marialuisa Bocchino; Renato Liguori; G. Liguori
BACKGROUND Pneumonias are the most frequent infectious disease, characterized by a high prevalence especially among children and adults at risk. The socio-economic impact caused by Streptococcus pneumoniae is evaluated in terms of morbidity, death rate and hospitalizations. OBJECTIVE The aim of the study was to demonstrate the potential economic advantages by implementation of an active anti-pneumococcal 13-valent vaccine strategy in Campania region ( Southern Italy) in two different categories of subjects, children (aged 0-12), and adults (aged 50-79) at risk (hypertension, nephropathies, COPD and heart diseases) Methods. Vaccination costs were compared with costs necessary to treat avoidable diseases in presence and absence of a vaccination program. RESULTS Offering anti-pneumococcal 13-valent vaccine to the paediatric population was quantified as saving one million euros for Italian national health service in two years. In addition , offering anti-pneumococcal vaccine to adults at risk would generate a return of around 29 million euros. CONCLUSION In both cases, offering anti-pneumococcal 13-valent vaccine was proven to be a helpful political health strategy, not only in consideration of a reduction of cases, but also in view of the favourable economic impacts.
European Journal of Public Health | 2018
F. Gallè; Valeria Di Onofrio; Alessandra Miele; Patrizia Belfiore; G. Liguori
BACKGROUND This study aimed to analyze the effects of a long-term community-based combined exercise program consisting of aerobic, resistance, flexibility and agility/balance training associated with motivational interviewing on physical fitness, physiological parameters and Physical Activity (PA) levels in middle-aged and older patients with Type 2 Diabetes (T2D). METHODS Sixty-nine diabetic subjects (mean age 63 ± 5.2 y, 62.3% M) underwent a 9-month exercise program and 12 motivational group meetings focused on PA, while 90 diabetic controls (mean age 64 ± 6.4 y, 58% M) underwent usual PA recommendations. Changes in physical fitness measured by Senior Fitness Tests, BMI, HbA1c, waist circumference (WC) and habitual PA expressed in Metabolic Equivalent of Tasks (METs)-min/week were evaluated in each group through the International PA Questionnaire and compared between groups. RESULTS At the end of the intervention participants showed significant improvements in BMI (29.3 to 27.6 kg/m2, P < 0.03), HbA1c (6.5 to 6.1%, P < 0.01), WC (104.2 to 95.6 cm, P < 0.01) and all the physical fitness parameters (P < 0.01) but lower body flexibility (P = 0.82), while only upper body strength (P = 0.04) and agility (P ≤ 0.01) improved significantly in controls. Habitual PA increased in participants and controls (+67 and +19 METs-min/week, respectively, P ≤ 0.01). Changes in physical fitness and PA levels registered in the two groups differed significantly (P < 0.01), while improvements in BMI, HbA1c and WC did not (P = 0.40, P = 0.52, P = 0.05, respectively). CONCLUSIONS A long-term motivational exercise-based intervention may be more effective than PA recommendations only in improving physical fitness and PA levels in individuals with T2D and produce similar health improvements.
BMC Public Health | 2018
Valeria Di Onofrio; F. Gallè; Mirella Di Dio; Patrizia Belfiore; G. Liguori
BackgroundType 2 diabetes (T2D) is associated with a prion diminished quality of life, especially due to the severe complications that it implicates. Changing dietary habits is an absolute priority, as well as implementing nutritional motivational programs. The aim of this study was to verify the effectiveness of a nutritional intervention in improving the health of patients affected by T2D.MethodsA total of 69 patients participated in a nine-months motivational program focused on the principles of the Mediterranean diet, the classes of nutrients, the distribution of the meals during the day and the dietary choices. During regular meetings, the patients were requested to fill out a questionnaire about their dietary habits and behaviours. Clinical and metabolic parameters were also analysed.ResultsAt the end of the intervention the number of people who declared that they ate five meals a day (p = 0.006) and preferred to have fruit for snack (p = 0.004) increased, while there was a reduction in the use of sweeteners and an elimination of the use of fructose (p = 0.05). The total daily consumption of kilocalories (kcal) had been reduced and the percentages of carbohydrates, proteins and lipids, after the intervention, follow the guidelines. In relation to this, a significant improvement (p < 0.05) was registered in systolic and diastolic pressure, BMI and waist circumference, as well as in glycaemic values (p = 0.018).ConclusionsA nutritional motivational intervention may be useful in improving dietary habits and health status of patients with T2D. We hope that a similar intervention will be applied in Campania and in other Italian regions.Trial registrationRegistration number is ISRCTN11067689; date of registration: 10/09/2018. Retrospectively registered.
Scandinavian Journal of Surgery | 2017
F. Gallè; Assunta Cirella; A. M. Salzano; V. Di Onofrio; Patrizia Belfiore; G. Liguori
Background and Aims: Personality disorders are frequently associated with eating disorders in obese patients and may negatively affect weight loss and maintenance after bariatric surgery. This non-randomized study aimed to assess the effects of different psychotherapeutic interventions on weight loss in a sample of patients with borderline personality disorder who underwent laparoscopic gastric bypass or laparoscopic adjustable gastric banding. Materials and Methods: A total of 153 bariatric patients meeting borderline personality disorder criteria were chosen voluntarily and consecutively to undergo an interpersonal individual treatment (n = 50), a dialectical behavioral group treatment (n = 50), or treatment as usual (n = 53) for a year after surgery. Their body mass index was measured before and at the end of each treatment. Results and Conclusion: A total of 12 patients (7.8%) dropped out of the study. Significantly higher body mass index reductions were registered in both experimental groups (−14.2 and −9.4 kg/m2, respectively) compared with the treatment as usual group (−2.1 kg/m2; p < 0.01). Treated patients who underwent laparoscopic gastric bypass (total n = 94) showed better outcomes than those who underwent laparoscopic adjustable gastric banding (total n = 45), while no differences were observed in untreated patients. This study demonstrates the role of pre-operative psychological assessment and post-operative psychotherapeutic support in improving weight loss among bariatric patients with borderline personality disorder. A randomized controlled trial is needed to confirm these preliminary findings.
Italian Journal of Public Health | 2012
Giorgio Liguori; Antonino Parlato; Alessandro Scaletti; Patrizia Belfiore; Paolo Russo; Francesca Gallè; Anna D'Ausilio; Maria Rosaria Granata; Francesco Pecci
Abstract : Background: although the efficacy of pneumococcal vaccination for the more common serotypes of Streptococcus pneumoniae has been demonstrated, the 13-valent vaccine (Prevenar 13®) is still offered in different ways in the Italian regional healthcare units, and in the region of campania, some local health authorities administer the vaccine free of charge whilst others practice a co-payment. Methods : we performed a budget impact analysis of the possible free administration of Prevenar 13® vaccine to all newborns in the campania region, by comparing two different delivery settings, one having an active vaccination program and another in which such program was absent. during the operation of the vaccination program, the number of expected cases with 50, 80 and 100% vaccine coverage in the popula- tion was considered. the economic advantage resulting from pneumococcal diseases deemed avoidable thanks to the vaccination was compared with the costs of the vaccination program. the analysis considered the direct costs in the 2 years after implementation of the vaccination program. costs were expressed in € euros 2010. Results : although we did not consider the benefits achievable in the 10 years following the vaccina- tion, nor the herd effects, we showed that offering anti-pneumococcal vaccination to all newborns could give economic advantages to the region, estimated as close to 1 million euros. Conclusion : the use of Prevenar 13® can be considered a greatly advantageous public health strategy....
Obesity Surgery | 2017
F. Gallè; Pietro Maida; Assunta Cirella; Elena Giuliano; Patrizia Belfiore; G. Liguori
Technology and Health Care | 2018
Patrizia Belfiore; Alessandro Scaletti; Alberto Frau; Maurizio Ripani; Vincenzo Romano Spica; G. Liguori
Value in Health | 2017
Patrizia Belfiore; A D'Ausilio; A Aiello; M Toumi; Alessandro Scaletti; A Frau; M Ripani; V Romano Spica; G. Liguori