Paul C. Unangst | Researchain

Network

Latest external collaboration on country level. Dive into details by clicking on the dots.

Explore More

Hotspot

Dive into the research topics where Paul C. Unangst is active.

Explore More

Publication

Featured researches published by Paul C. Unangst.

Bioorganic & Medicinal Chemistry Letters | 1993

Oxazole, thiazole, and imidazole derivatives of 2,6-di-tert-butylphenol as dual 5-lipoxygenase and cyclooxygenase inhibitors

Paul C. Unangst; David T. Connor; Wiaczeslaw Antin Cetenko; Roderick J. Sorenson; Jagadish C. Sircar; Clifford D. Wright; Denis J. Schrier; Richard D. Dyer

Benzylidene di-tert-butylphenols containing oxazole, thiazole, and imidazole substituents are dual inhibitors of 5-lipoxygenase and cyclooxygenase with IC50 values <5 μM. The oxazole and thiazole analogs exhibit oral antiinflammatory activity.

Journal of Medicinal Chemistry | 1992

Novel 1,2,4-oxadiazoles and 1,2,4-thiadiazoles as dual 5-lipoxygenase and cyclooxygenase inhibitors

Paul C. Unangst; Gary P. Shrum; David T. Connor; Richard D. Dyer; Denis J. Schrier

Journal of Medicinal Chemistry | 1994

Synthesis and biological evaluation of 5-[[3,5-bis(1,1-dimethylethyl)-4-hydroxyphenyl]methylene]oxazoles, -thiazoles, and -imidazoles: novel dual 5-lipoxygenase and cyclooxygenase inhibitors with antiinflammatory activity

Paul C. Unangst; David T. Connor; Wiaczeslaw Antin Cetenko; Roderick J. Sorenson; Catherine R. Kostlan; Jagadish C. Sircar; Clifford D. Wright; Denis J. Schrier; Richard D. Dyer

Journal of Medicinal Chemistry | 1989

Novel indolecarboxamidotetrazoles as potential antiallergy agents

Paul C. Unangst; David T. Connor; Stabler; Weikert Rj; Mary E. Carethers; John A. Kennedy; David Orel Thueson; J.C. Chestnut; R.L. Adolphson; Mary Carol Conroy

Journal of Medicinal Chemistry | 1992

Novel benzothiophene-, benzofuran-, and naphthalenecarboxamidotetrazoles as potential antiallergy agents.

David T. Connor; Cetenko Wa; Mullican; Roderick J. Sorenson; Paul C. Unangst; Weikert Rj; R.L. Adolphson; John A. Kennedy; David Orel Thueson; Clifford D. Wright

Journal of Heterocyclic Chemistry | 1987

Synthesis of novel 1-phenyl-1H-indole-2-carboxylic Acids. I. Utilization of ullmann and dieckmann reactions for the preparation of 3-hydroxy, 3-alkoxy, and 3-alkyl derivatives

Paul C. Unangst; David T. Connor; S Russell Stabler; Robert James Weikert

Journal of Medicinal Chemistry | 1980

Synthesis and antiallergy activity of 4-oxopyrano[3,2-b]indoles

Paul C. Unangst; Richard E. Brown; David J. Herzig

Journal of Medicinal Chemistry | 1984

Acidic furo[3,2-b]indoles. A new series of potent antiallergy agents

Paul C. Unangst; Mary E. Carethers; Kenneth Webster; Grace M. Janik; Lillian Robichaud

Journal of Heterocyclic Chemistry | 1993

Preparation of novel 1,2,4-thiadiazoles by cyclization with 4-methylbenzenesulfonyl cyanide (tosyl cyanide)

Paul C. Unangst; Gary P. Shrum; David T. Connor

Journal of Heterocyclic Chemistry | 1987

Synthesis of novel 1-phenyl-1H-indole-2-carboxylic acids. II. Preparation of 3-dialkylamino, 3-alkylthio, 3-alkylsulfinyl, and 3-alkylsulfonyl derivatives

Paul C. Unangst; David T. Connor; S Russell Stabler

Explore More

Collaboration

Dive into the Paul C. Unangst's collaboration.

Top Co-Authors

Richard E. Brown

Parke-Davis

View shared research outputs

Explore More

Archive Network Publication Hotspot Collaboration

Network

Latest external collaboration on country level. Dive into details by clicking on the dots.

Hotspot

Dive into the research topics where Paul C. Unangst is active.

Publication

Featured researches published by Paul C. Unangst.

Oxazole, thiazole, and imidazole derivatives of 2,6-di-tert-butylphenol as dual 5-lipoxygenase and cyclooxygenase inhibitors

Novel 1,2,4-oxadiazoles and 1,2,4-thiadiazoles as dual 5-lipoxygenase and cyclooxygenase inhibitors

Synthesis and biological evaluation of 5-[[3,5-bis(1,1-dimethylethyl)-4-hydroxyphenyl]methylene]oxazoles, -thiazoles, and -imidazoles: novel dual 5-lipoxygenase and cyclooxygenase inhibitors with antiinflammatory activity

Novel indolecarboxamidotetrazoles as potential antiallergy agents

Novel benzothiophene-, benzofuran-, and naphthalenecarboxamidotetrazoles as potential antiallergy agents.

Synthesis of novel 1-phenyl-1H-indole-2-carboxylic Acids. I. Utilization of ullmann and dieckmann reactions for the preparation of 3-hydroxy, 3-alkoxy, and 3-alkyl derivatives

Synthesis and antiallergy activity of 4-oxopyrano[3,2-b]indoles

Acidic furo[3,2-b]indoles. A new series of potent antiallergy agents

Preparation of novel 1,2,4-thiadiazoles by cyclization with 4-methylbenzenesulfonyl cyanide (tosyl cyanide)

Synthesis of novel 1-phenyl-1H-indole-2-carboxylic acids. II. Preparation of 3-dialkylamino, 3-alkylthio, 3-alkylsulfinyl, and 3-alkylsulfonyl derivatives

Collaboration

Dive into the Paul C. Unangst's collaboration.