Network


Latest external collaboration on country level. Dive into details by clicking on the dots.

Hotspot


Dive into the research topics where Paul C. Unangst is active.

Publication


Featured researches published by Paul C. Unangst.


Bioorganic & Medicinal Chemistry Letters | 1993

Oxazole, thiazole, and imidazole derivatives of 2,6-di-tert-butylphenol as dual 5-lipoxygenase and cyclooxygenase inhibitors

Paul C. Unangst; David T. Connor; Wiaczeslaw Antin Cetenko; Roderick J. Sorenson; Jagadish C. Sircar; Clifford D. Wright; Denis J. Schrier; Richard D. Dyer

Benzylidene di-tert-butylphenols containing oxazole, thiazole, and imidazole substituents are dual inhibitors of 5-lipoxygenase and cyclooxygenase with IC50 values <5 μM. The oxazole and thiazole analogs exhibit oral antiinflammatory activity.


Journal of Medicinal Chemistry | 1992

Novel 1,2,4-oxadiazoles and 1,2,4-thiadiazoles as dual 5-lipoxygenase and cyclooxygenase inhibitors

Paul C. Unangst; Gary P. Shrum; David T. Connor; Richard D. Dyer; Denis J. Schrier


Journal of Medicinal Chemistry | 1994

Synthesis and biological evaluation of 5-[[3,5-bis(1,1-dimethylethyl)-4-hydroxyphenyl]methylene]oxazoles, -thiazoles, and -imidazoles: novel dual 5-lipoxygenase and cyclooxygenase inhibitors with antiinflammatory activity

Paul C. Unangst; David T. Connor; Wiaczeslaw Antin Cetenko; Roderick J. Sorenson; Catherine R. Kostlan; Jagadish C. Sircar; Clifford D. Wright; Denis J. Schrier; Richard D. Dyer


Journal of Medicinal Chemistry | 1989

Novel indolecarboxamidotetrazoles as potential antiallergy agents

Paul C. Unangst; David T. Connor; Stabler; Weikert Rj; Mary E. Carethers; John A. Kennedy; David Orel Thueson; J.C. Chestnut; R.L. Adolphson; Mary Carol Conroy


Journal of Medicinal Chemistry | 1992

Novel benzothiophene-, benzofuran-, and naphthalenecarboxamidotetrazoles as potential antiallergy agents.

David T. Connor; Cetenko Wa; Mullican; Roderick J. Sorenson; Paul C. Unangst; Weikert Rj; R.L. Adolphson; John A. Kennedy; David Orel Thueson; Clifford D. Wright


Journal of Heterocyclic Chemistry | 1987

Synthesis of novel 1-phenyl-1H-indole-2-carboxylic Acids. I. Utilization of ullmann and dieckmann reactions for the preparation of 3-hydroxy, 3-alkoxy, and 3-alkyl derivatives

Paul C. Unangst; David T. Connor; S Russell Stabler; Robert James Weikert


Journal of Medicinal Chemistry | 1980

Synthesis and antiallergy activity of 4-oxopyrano[3,2-b]indoles

Paul C. Unangst; Richard E. Brown; David J. Herzig


Journal of Medicinal Chemistry | 1984

Acidic furo[3,2-b]indoles. A new series of potent antiallergy agents

Paul C. Unangst; Mary E. Carethers; Kenneth Webster; Grace M. Janik; Lillian Robichaud


Journal of Heterocyclic Chemistry | 1993

Preparation of novel 1,2,4-thiadiazoles by cyclization with 4-methylbenzenesulfonyl cyanide (tosyl cyanide)

Paul C. Unangst; Gary P. Shrum; David T. Connor


Journal of Heterocyclic Chemistry | 1987

Synthesis of novel 1-phenyl-1H-indole-2-carboxylic acids. II. Preparation of 3-dialkylamino, 3-alkylthio, 3-alkylsulfinyl, and 3-alkylsulfonyl derivatives

Paul C. Unangst; David T. Connor; S Russell Stabler

Collaboration


Dive into the Paul C. Unangst's collaboration.

Top Co-Authors

Avatar
Researchain Logo
Decentralizing Knowledge