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Dive into the research topics where Paul I. Reynolds is active.

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Featured researches published by Paul I. Reynolds.


Journal of Clinical Anesthesia | 1997

Cancellation of pediatric outpatient surgery: Economic and emotional implications for patients and their families

Alan R. Tait; Terri Voepel-Lewis; Hamish M. Munro; Howard B. Gutstein; Paul I. Reynolds

Abstract Study Objective: To determine the cause and timing of case cancellation in a pediatric outpatient surgical population, and to examine the economic and emotional impact of such cancellations on patients and their families. Design: Questionnaire survey. Setting: Outpatient surgery unit of a large university childrens hospital. Participants: 127 parents of children whose elective outpatient surgery had been cancelled. Interventions: A total of 200 questionnaires were mailed to the parents of children who had their outpatient surgery cancelled. Measurements and Main Results: Of those children whose surgery had been cancelled, 34.6% were due to upper respiratory infections (URIs), 30.7% for other medical reasons, and the balance for scheduling errors, because the child had not fasted, or for difficulties with transportation. The majority of surgeries (58.3%) were cancelled prior to their scheduled surgery date. However, 18.9% were cancelled on the day of surgery prior to leaving for the hospital and 22.8% were cancelled on arrival at the outpatient surgery clinic. Of those patients whose surgeries were not cancelled until they arrived at the hospital, 38.5% of mothers and 50.0% of fathers missed a day of work and, of these, 53.3% and 42.1%, respectively, went unpaid for the work day missed. The mean number of miles driven (round trip) to the hospital for a cancelled operation was 158.8 miles (range 8 to 1,350 miles). Additional testing and new appointments were ordered in 25.2% of the cancelled cases. 45% of parents and 16% of children were disappointed by the cancellation; 16% of parents were frustrated by the cancellation and 3.3% were angry. Conclusions: This study suggests that last-minute cancellation of surgery has an important impact on patients and their families and suggests a need to review present protocols for screening patients prior to surgery.


Anesthesia & Analgesia | 1993

Propofol infusion and the incidence of emesis in pediatric outpatient strabismus surgery.

Patricia M. Weir; Hamish M. Munro; Paul I. Reynolds; Ian H. Lewis; Niall Wilton

A prospective, randomized, double-blind study was conducted to examine the effect of a propofol infusion on the incidence of postoperative emesis in children undergoing outpatient strabismus surgery. Seventy-eight children, aged 3-12 yr, were allocated randomly to receive either nitrous oxide and halothane or nitrous oxide and a propofol infusion for the maintenance of anesthesia. The overall incidence of vomiting during the first 24 h was 64% in those receiving halothane and 41% in those receiving the propofol infusion; this difference was statistically significant (P < 0.05). In children who received no opioids postoperatively, the incidence of vomiting in the first 24 h was 71% in the halothane group and 24% in the propofol group; this difference was also significant (P = 0.001). We conclude that propofol was effective in reducing the incidence of postoperative emesis in pediatric outpatient strabismus surgery.


Anesthesia & Analgesia | 2000

False Alarms and Sensitivity of Conventional Pulse Oximetry Versus the Masimo Set™ Technology in the Pediatric Postanesthesia Care Unit

Shobha Malviya; Paul I. Reynolds; Terri Voepel-Lewis; Monica Siewert; David Watson; Alan R. Tait; Kevin K. Tremper

We compared the incidence and duration of false alarms (FA)and the sensitivity of conventional pulse oximetry (CPO) with Masimo Signal Extraction Technology™ (Masimo SET™; Masimo Corporation, Irvine, CA) in children in the postanesthesia care unit. Disposable oximeter sensors were placed on separate digits of one extremity. Computerized acquisition of synchronous data included electrocardiograph heart rate, Spo2, and pulse rate via CPO and Masimo SET™. Patient motion, respiratory, and other events were simultaneously documented. Spo2 tracings conflicting with clinical observations and/or documented events were considered false. These were defined as 1) Data dropout, complete interruption in Spo2 data; 2) False negative, failure to detect Spo2 ≤ 90% detected by another device or based on observation/intervention; 3) FA, Spo2 ≤ 90% considered artifactual; and 4) True alarm (TA), Spo2 ≤ 90% considered valid. Seventy-five children were monitored for 35 ± 22 min/patient (42 h total). There were 27 TAs, all of which were identified by Masimo SET™ and only 16 (59%) were identified by CPO (P < 0.05). There was twice the number of FAs with CPO (10 vs 4 Masimo SET™;P < 0.05). The incidence and duration of data dropouts were similar between Masimo SET™ and CPO. Masimo SET™ reduced the incidence and duration of FAs and identified a more frequent incidence of TAs compared with CPO. Implications Pulse oximetry that incorporates Masimo Signal Extraction Technology™ (Masimo Corporation, Irvine, CA) may offer an advantage over conventional pulse oximetry by reducing the incidence of false alarms while identifying a higher number of true alarms in children in the postanesthesia care unit.


Pediatric Anesthesia | 2007

Childhood body mass index and perioperative complications

Olubukola O. Nafiu; Paul I. Reynolds; Olumuyiwa A. Bamgbade; Kevin K. Tremper; Kathy Welch; Josephine Z. Kasa-Vubu

Background:  Our aim was to describe the incidence of quality assurance events between overweight/obese and normal weight children.


Pediatric Anesthesia | 2009

How do pediatric anesthesiologists define intraoperative hypotension

Olubukola O. Nafiu; Terri Voepel-Lewis; Michelle Morris; Wilson T. Chimbira; Shobha Malviya; Paul I. Reynolds; Kevin K. Tremper

Introduction:  Although blood pressure (BP) monitoring is a recommended standard of care by the ASA, and pediatric anesthesiologists routinely monitor the BP of their patients and when appropriate treat deviations from ‘normal’, there is no robust definition of hypotension in any of the pediatric anesthesia texts or journals. Consequently, what constitutes hypotension in pediatric anesthesia is currently unknown. We designed a questionnaire‐based survey of pediatric anesthesiologists to determine the BP ranges and thresholds used to define intraoperative hypotension (IOH).


Pediatric Anesthesia | 2004

Pentobarbital vs chloral hydrate for sedation of children undergoing MRI: efficacy and recovery characteristics.

Shobha Malviya; Terri Voepel-Lewis; Alan R. Tait; Paul I. Reynolds; Sachin Gujar; Stephen S. Gebarski; O. Petter Eldevik

Background : Chloral hydrate (CH) sedation for magnetic resonance imaging (MRI) is associated with significant failure rates, adverse events and delayed recovery. Pentobarbital (PB), reportedly produces successful sedation in 98% of children undergoing diagnostic imaging. This study compared the efficacy, adverse events and recovery characteristics of CH vs PB in children undergoing MRI.


Pediatric Anesthesia | 2009

Incidence and risk factors for preincision hypotension in a noncardiac pediatric surgical population

Olubukola O. Nafiu; Sachin Kheterpal; Michelle Morris; Paul I. Reynolds; Shobha Malviya; Kevin K. Tremper

Background:  Routine monitoring of blood pressure is an essential part of perioperative care in adults and children. It is however not known whether intraoperative hypotension (IOH) is clinically important in the ‘healthy’ pediatric patient. This may be partly due to the lack of data on the incidence and consequences of IOH in this group of patients. We utilized the Brain Trauma Foundation definition of hypotension to describe the incidence of preincision hypotension (PIH) in a large pediatric noncardiac surgical population and identified risk factors for the occurrence PIH.


Catheterization and Cardiovascular Diagnosis | 1996

Stent redilation in canine models of congenital heart disease: Pulmonary artery stenosis and coarctation of the aorta

Alan M. Mendelsohn; Parvin C. Dorostkar; Catherine Moorehead; Flavian M. Lupinetti; Paul I. Reynolds; Achi Ludomirsky; Thomas R. Lloyd; Kathleen P. Heidelberger; Robert H. Beekman

In a canine puppy model, pulmonary artery stenosis was created by banding the left pulmonary artery to 30-40% of its original diameter. Animals underwent right heart catheterization and angiography 1-2 mo later, and Palmaz P308 stents were implanted. Stent redilation was performed 3-5 mo later. One mo postredilation, the animals were restudied and sacrificed. Coarctations of the aorta were created by transverse aortic incision and longitudinal repair. P308 stent implantation was performed 2-3 mo later. Stent redilation was performed after 6-10 mo, and the animals were restudied and sacrificed 1-2 mo later. Stent implantation was performed in 6 puppies with pulmonary artery stenosis, as 2 animals developed postoperative pulmonary arterial hypoplasia, precluding stenting. The stenosis diameter increased from 4.8 +/- 0.5 mm to 7.4 +/- 0.6 mm (mean +/- SE) following stenting (P = 0.005), and increased further to 9.2 +/- 0.7 mm following redilation (P < 0.001). There were no significant vessel tears or ruptures. Coarctation stenting was performed in 8 animals. The coarctation was dilated from 5.8 +/- 0.9 mm to 9.8 +/- 0.6 mm (P < 0.001), and to 13.5 +/- 0.5 mm at redilation (P = 0.002). Redilation could not be performed in 1 animal. Aortic rupture and death occurred in 2 of 7 animals at redilation. Stent implantation and redilation in experimental pulmonary artery stenosis appears safe and effective. Though stent implantation for coarctation of the aorta appears safe, there was a 28% aortic rupture rate at stent redilation in this model.


Journal of Cardiothoracic and Vascular Anesthesia | 1996

Lumbar epidural morphine infusions for children undergoing cardiac surgery

Jay R. Shayevitz; Sandra Merkel; Sean W O'Kelly; Paul I. Reynolds; Howard B. Gutstein

OBJECTIVE To determine whether outcomes and costs in children undergoing cardiac surgery are affected by the method of postoperative pain management. DESIGN Retrospective, case control. SETTING Tertiary care childrens hospital in a university setting. PARTICIPANTS Two groups of children undergoing cardiac surgery for palliation or repair of congenital heart disease oer a 21-month period between January 1993 and September 1994. INTERVENTIONS Lumbar epidural morphine infusions (LEM) in one group, and IV opioid (IVO) medication in the other for postoperative pain control. MEASUREMENTS AND MAIN RESULTS Hospital courses of 27 LEM patients and 27 IVO patients were analyzed. In LEM patients, epidural catheters were placed following anesthetic induction, but before anticoagulation. A bolus of 50 micrograms/kg of preservative-free morphine sulfate was administered through the catheter, followed by a continuous infusion at 3 to 4 micrograms/kg/h for 22 to 102 (median, 46) hours postoperatively. The IVO patients received 50 micrograms/kg, IV, of fentanyl before incision followed by a continuous infusion at 0.3 microgram/kg/min. The fentanyl infusion rate was decreased to 0.1 microgram/kg/min postoperatively and maintained for 24 hours. Although the LEM group was demographically similar to the IVO group, times to tracheal extubation, transfer from the intensive care unit, and resumption of regular diet were significantly shorter in LEM patients. LEM and IVO patients received similar amounts of fentanyl during surgery (10.4 +/- 19.3 micrograms/kg/h v 13.7 +/- 8.1 micrograms/kg/h, p = 0.4). However, during postoperative recovery, LEM patients who were extubated late received significantly less supplemental opioid medication than IVO patients extubated late during the first 5 postoperative days. No complications related to dural puncture, bleeding into the epidural space, or respiratory depression were encountered. Pruritus and nausea/vomiting were the most commonly reported morbidities in both groups. Fifty-six percent (15/27) of LEM patients and 41% of IVO patients reported pruritus (p = 0.4). There was no significant difference in the incidence of nausea and vomiting between the groups (34% v 30%, respectively). CONCLUSIONS Given the present methodologic limitations, the authors found improved outcomes only in LEM patients extubated late compared with IVO patients. Randomized, prospective studies to evaluate this conclusion and to determine the comparative efficacy and safety of LEM infusions are in progress.


Pediatric Anesthesia | 2003

Increased respiratory symptoms following surgery in children exposed to environmental tobacco smoke.

Robert A. Drongowski; Donald Lee; Paul I. Reynolds; Shobha Malviya; Carroll M. Harmon; James D. Geiger; Joseph L. Lelli; Arnold G. Coran

Objective: The aim of this study was to determine if children exposed to environmental tobacco smoke (ETS) via parental smoking (ETS+) developed more respiratory symptoms resulting in longer recovery times following surgical outpatient procedures compared with children of nonsmoking parents (ETS−).

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