Paul M. Margosian

Magnetic resonance imaging system with thin cylindrical uniform field volume and moving subjects

A magnetic resonance gantry (A) includes a magnet (12) which generates a uniform magnetic field in a thin (under 15 cm thick) imaging volume (10). Gradient coils (30) and radio frequency coils (20) transmit radio frequency and gradient magnetic field pulses of conventional imaging sequences into the imaging volume. A patient support surface (42) moves a patient continuously through the imaging volume as the pulses of the magnetic resonance sequence are applied. A tachometer (52) monitors movement of the patient. A frequency scaler (54) scales the frequency of the RF excitation pulses applied by the transmitter (22) and the demodulation frequency of the receiver (26) in accordance with the patient movement such that the selected slice moves in synchrony with the patient through the imaging volume. The slice select gradient is indexed after magnetic resonance signals to generate a full set of views for reconstruction into a two-dimensional image representation of the slice are generated. The views for each slice are reconstructed (28) into a three-dimensional image representation that is stored in a memory (60). By using rapid imaging techniques, such as echo-planar techniques which can generate a two-dimensional image of a slice in 150 milliseconds, a three-dimensional diagnostic image of a section of a subject one meter long can be generated in less than 2 minutes.

Multiple contrast fast spin-echo approach to black-blood intracranial MRA: Use of complementary and supplementary information

Black-blood magnetic resonance angiography (black-blood MRA) could be considered an alternative to time-of-flight (TOF) MRA. In the cases of irregular flow conditions, it could be more advantageous than time-of-flight (TOF) MRA in providing vessel definition and delineation. Proton-density weighted (PDW) multi-slab three-dimensional fast spin-echo (3DFSE) sequences have been used to generate black-blood MRA. Unfortunately, multi-planar reformatted 3DFSE images often exhibit slab boundary artifacts (intensity variation in the slice direction) which create dark bands interfering with the identification of dark blood vessels. Furthermore, PDW measurements fail to darken slow flowing or re-circulating blood in some circumstances. In this work, a dual-contrast multi-slab 3DFSE acquisition is used to approach black-blood MRA. This sequence simultaneously provides proton-density weighted (PDW) and T(2)-weighted (T2W) images which can be further integrated together to produce black-blood angiograms gained by utilizing complementary contrast and supplementary vascular information. Additionally, a technique of suppressing slab boundary artifact has been incorporated into this sequence. This approach provides: i) good SNR measurement of anatomy for the PDW image and optimal black-blood angiograms from the T2W image; ii) scan time efficiency (dual-contrast image sets plus black-blood angiograms within one acquisition); and iii) suppressed slab boundary artifacts as well as minimized mis-registration error.