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Featured researches published by Paul Pugliese.


Journal of Nuclear Medicine Technology | 2008

Pinhole Versus Parallel-Hole Collimators for Parathyroid Imaging: An Intraindividual Comparison

Maria B. Tomas; Paul Pugliese; Gene Tronco; Charito Love; Christopher J. Palestro; Kenneth Nichols

This study was undertaken to determine the effects of collimators on the accuracy of preoperative sestamibi parathyroid imaging of the neck. Methods: Forty-nine patients with primary hyperparathyroidism underwent preoperative 99mTc-sestamibi parathyroid imaging. The protocol included early and late pinhole and parallel-hole imaging. One experienced nuclear physician, without knowledge of other test results or final diagnoses, interpreted studies. For both pinhole and parallel-hole images, focally increased sestamibi accumulation outside the normal tracer biodistribution that persisted or increased in intensity from early to late images was interpreted as positive for a parathyroid lesion. Final diagnoses were operatively confirmed in all patients. Results: Fifty-four parathyroid lesions were resected from the 49 patients. Forty-five patients had single-gland disease. Four patients had multigland disease: 3 had 2 lesions and 1 had 3 lesions. Median lesion weight was 840 mg. Pinhole imaging was significantly more sensitive than parallel-hole imaging (89% vs. 56%; P = 0.0003) for all 54 lesions. Specificity did not significantly differ between pinhole and parallel-hole imaging (93% vs. 96%, P = 0.29). Pinhole imaging was significantly more sensitive than parallel-hole imaging for lesions above (100% vs. 68%, P = 0.003) and below (77% vs. 42%, P = 0.03) the median weight and for single-gland disease (96% vs. 67%, P = 0.001). Pinhole imaging also was more sensitive for multigland disease, although the difference was only marginally significant (55% vs. 0%, P = 0.037). Conclusion: Because sensitivity is significantly higher, sestamibi parathyroid imaging of the neck should be performed with a pinhole collimator.


Radiographics | 2001

Role of Nuclear Medicine in Diagnosis of the Infected Joint Replacement

Charito Love; Maria B. Tomas; Scott E. Marwin; Paul Pugliese; Christopher J. Palestro


Radiology | 2006

PET with FDG-labeled leukocytes versus scintigraphy with 111In-oxine-labeled leukocytes for detection of infection.

Josephine Rini; Kuldeep K. Bhargava; Gene Tronco; Carol Singer; Russell Caprioli; Scott E. Marwin; Hugh L. Richardson; Kenneth Nichols; Paul Pugliese; Christopher J. Palestro


Radiographics | 2002

Pulmonary Activity on Labeled Leukocyte Images: Physiologic, Pathologic, and Imaging Correlation

Charito Love; Patrick Opoku-Agyemang; Maria B. Tomas; Paul Pugliese; Kuldeep K. Bhargava; Christopher J. Palestro


Society of Nuclear Medicine Annual Meeting Abstracts | 2006

Phase II study of 99mTc-ciprofloxacin uptake in patients with high suspicion of osteomyelitis

Christopher Palestro; Charito Love; Russell Caprioli; Scott E. Marwin; Hugh L. Richardson; John Haight; Gene Tronco; Paul Pugliese; Kuldeep K. Bhargava


The Journal of Nuclear Medicine | 2013

Relationship between cell concentration and image quality of 111In-labeled leukocyte scans

Fritzgerald Leveque; Kuldeep K. Bhargava; Paul Pugliese; Kenneth Nichols; Christopher J. Palestro


The Journal of Nuclear Medicine | 2012

Quantitative image characteristics of presynaptic dopamine transporter (DAT) scans

Fritzgerald Leveque; Paul Pugliese; Maria B. Tomas; Jaimie Kim; Kenneth Nichols; Christopher J. Palestro


The Journal of Nuclear Medicine | 2012

111In-oxine leukocyte labeling: Intraindividual comparison of leukocyte isolation methods: Conventional versus automated microfluidic chip

Christopher J. Palestro; Kuldeep K. Bhargava; Kenneth Nichols; Paul Pugliese; Alan J. Fischman; Ronald G. Tompkins; Tom Barber; Ravi Kapur; Mehmet Toner


Society of Nuclear Medicine Annual Meeting Abstracts | 2012

Analysis of the composition of 111In-labeled leukocyte preparation used for imaging inflammation and infection

Fritzgerald Leveque; Kuldeep K. Bhargava; Kenneth Nichols; Paul Pugliese; Christopher Palestro


Society of Nuclear Medicine Annual Meeting Abstracts | 2011

Factors affecting estimates of pulmonary shunting prior to 90Y selective internal radiotherapy

Fritzgerald Leveque; Paul Pugliese; Sherry Reyes; Christopher Palestro; Kenneth Nichols

Collaboration


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Kenneth Nichols

North Shore-LIJ Health System

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Christopher Palestro

Albert Einstein College of Medicine

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Kuldeep K. Bhargava

North Shore-LIJ Health System

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Fritzgerald Leveque

North Shore-LIJ Health System

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Charito Love

North Shore-LIJ Health System

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Gene Tronco

North Shore-LIJ Health System

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Scott E. Marwin

North Shore-LIJ Health System

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Maria B. Tomas

North Shore-LIJ Health System

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Hugh L. Richardson

Long Island Jewish Medical Center

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