Paul Rood
Radboud University Nijmegen
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Publication
Featured researches published by Paul Rood.
Journal of the American Geriatrics Society | 2017
Tianne Numan; Mark van den Boogaard; Adriaan M. Kamper; Paul Rood; Linda M. Peelen; Arjen J. C. Slooter
To evaluate to what extent delirium experts agree on the diagnosis of delirium when independently assessing exactly the same information and to evaluate the sensitivity of delirium screening tools in routine daily practice of clinical nurses.
International Journal of Nursing Studies | 2017
Annelies Wassenaar; Paul Rood; Lisette Schoonhoven; Steven Teerenstra; Marieke Zegers; Peter Pickkers; Mark van den Boogaard
BACKGROUND Delirium is a common disorder in Intensive Care Unit (ICU) patients and is associated with serious short- and long-term consequences, including re-intubations, ICU readmissions, prolonged ICU and hospital stay, persistent cognitive problems, and higher mortality rates. Considering the high incidence of delirium and its consequences, prevention of delirium is imperative. This study focuses on a program of standardized nursing and physical therapy interventions to prevent delirium in the ICU, called UNDERPIN-ICU (nUrsiNg DEliRium Preventive INterventions in the ICU). OBJECTIVE To determine the effect of the UNDERPIN-ICU program on the number of delirium-coma-free days in 28days and several secondary outcomes, such as delirium incidence, the number of days of survival in 28 and 90days and delirium-related outcomes. DESIGN AND SETTING A multicenter stepped wedge cluster randomized controlled trial. METHODS Eight to ten Dutch ICUs will implement the UNDERPIN-ICU program in a randomized order. Every two months the UNDERPIN-ICU program will be implemented in an additional ICU following a two months period of staff training. UNDERPIN-ICU consists of standardized protocols focusing on several modifiable risk factors for delirium, including cognitive impairment, sleep deprivation, immobility and visual and hearing impairment. PARTICIPANTS ICU patients aged ≥18years (surgical, medical, or trauma) and at high risk for delirium, E-PRE-DELIRIC ≥35%, will be included, unless delirium was detected prior ICU admission, expected length of ICU stay is less then one day or when delirium assessment is not possible. DISCUSSION For every intervention the balance between putative benefit and potential unwanted side effects needs to be considered. In non-ICU patients, it has been shown that a similar program resulted in a significant reduction of delirium incidence and duration. Recent small studies using multi component interventions to prevent delirium in ICU patients have also shown beneficial effect, without unwanted side effects. We therefore feel that the proportionality of potential positive effects of the UNDERPIN-ICU program, weighed against potential unwanted side effects is favourable. Since this has not been rigorously proven in ICU patients, we will study the effects of this program in ICU patients using a stepped wedge design. TRIAL REGISTRATION The study is registered in the clinical trials registry: https://clinicaltrials.gov/. REPORTING METHOD Standard Protocol Items: Recommendations for Interventional Trails (SPIRIT).
Acta Paediatrica | 2016
Kim Kamphorst; Ydelette Sietsma; Aj Brouwer; Paul Rood; Agnes van den Hoogen
Early full enteral feeding in preterm infants decreases morbidity and mortality. Our systematic review covered the effectiveness of rectal stimulation, suppositories and enemas on stooling patterns and feeding tolerance in low‐birthweight infants born at up to 32 weeks. It comprised seven studies published between 2007 and 2014 and covered 495 infants.
BJA: British Journal of Anaesthesia | 2018
T. Numan; M.H.W.A. van den Boogaard; A.M. Kamper; P.J.T. Rood; Linda M. Peelen; A.J.C. Slooter; Masieh Abawi; Mark van den Boogaard; Jurgen A.H.R. Claassen; Michael Coesmans; Paul L. J. Dautzenberg; Ton Adf. Dhondt; Shiraz B. Diraoui; Piet Eikelenboom; Marielle H. Emmelot-Vonk; Richard A. Faaij; Willem A. van Gool; Erwin R. Groot; Carla Hagestein-de Bruijn; Jacqueline G. F. M. Hovens; Mathieu van der Jagt; Anne-Marieke de Jonghe; Adriaan M. Kamper; Huiberdine L. Koek; Arendina W. van der Kooi; Marjan Kromkamp; Joep Lagro; Albert F.G. Leentjens; Geert J. Lefeber; Frans S. S. Leijten
Background: Delirium is frequently unrecognised. EEG shows slower frequencies (i.e. below 4 Hz) during delirium, which might be useful in improving delirium recognition. We studied the discriminative performance of a brief single‐channel EEG recording for delirium detection in an independent cohort of patients. Methods: In this prospective, multicentre study, postoperative patients aged ≥60 yr were included (n=159). Before operation and during the first 3 postoperative days, patients underwent a 5‐min EEG recording, followed by a video‐recorded standardised cognitive assessment. Two or, in case of disagreement, three delirium experts classified each postoperative day based on the video and chart review. Relative delta power (1–4 Hz) was based on 1‐min artifact‐free EEG. The diagnostic value of the relative delta power was evaluated by the area under the receiver operating characteristic curve (AUROC), using the expert classification as the gold standard. Results: Experts classified 84 (23.3%) postoperative days as either delirium or possible delirium, and 276 (76.7%) non‐delirium days. The AUROC of the relative EEG delta power was 0.75 [95% confidence interval (CI) 0.69–0.82]. Exploratory analysis showed that relative power from 1 to 6 Hz had significantly higher AUROC (0.78, 95% CI 0.72–0.84, P=0.014). Conclusions: Delirium/possible delirium can be detected in older postoperative patients based on a single‐channel EEG recording that can be automatically analysed. This objective detection method with a continuous scale instead of a dichotomised outcome is a promising approach for routine detection of delirium. Clinical trial registration: NCT02404181.
American Journal of Critical Care | 2018
Koen S. Simons; Enzio R. K. Boeijen; Marlies C. Mertens; Paul Rood; Cornelis P. C. de Jager; Mark van den Boogaard
Background Exposure to bright light has alerting effects. In nurses, alertness may be decreased because of shift work and high work pressure, potentially reducing work performance and increasing the risk for medical errors. Objectives To determine whether high‐intensity dynamic light improves cognitive performance, self‐reported depressive signs and symptoms, fatigue, alertness, and well‐being in intensive care unit nurses. Methods In a single‐center crossover study in an intensive care unit of a teaching hospital in the Netherlands, 10 registered nurses were randomly divided into 2 groups. Each group worked alternately for 3 to 4 days in patients’ rooms with dynamic light and 3 to 4 days in control lighting settings. High‐intensity dynamic light was administered through ceiling‐mounted fluorescent tubes that delivered bluish white light up to 1700 lux during the daytime, versus 300 lux in control settings. Cognitive performance, self‐reported depressive signs and symptoms, fatigue, and well‐being before and after each period were assessed by using validated cognitive tests and questionnaires. Results Cognitive performance, self‐reported depressive signs and symptoms, and fatigue did not differ significantly between the 2 light settings. Scores of subjective well‐being were significantly lower after a period of working in dynamic light. Conclusions Daytime lighting conditions did not affect intensive care unit nurses’ cognitive performance, perceived depressive signs and symptoms, or fatigue. Perceived quality of life, predominantly in the psychological and environmental domains, was lower for nurses working in dynamic light.
Intensive Care Medicine Experimental | 2015
Paul Rood; Peter Pickkers; J.G. van der Hoeven; M.H.W.A. van den Boogaard
Sleep is a fundamental need for recovery while a lack of good sleep is associated with adverse effects. ICU patients have an increased risk for disturbed sleep. Various sleeping questionnaires have been developed to assess the different aspects of sleep. The Richards Campbell Sleep Questionnaire (RCSQ) is one of the most commonly used sleep assessment tools for the ICU consisting of 5 questions on different aspects of sleep and reasons for poor sleep. However, it seems irrelevant to burden patients that state to have a good night sleep with the complete RCSQ. For clinical and developmental use it is useful to quantify sleep in a simple and effective manner. Therefore, the aim of our study was to investigate a simple sleeping numeric rating score; NRS sleep.
Intensive Care Medicine Experimental | 2015
Annelies Wassenaar; M.H.W.A. van den Boogaard; Paul Rood; Lisette Schoonhoven; Peter Pickkers
Delirium is common in Intensive Care Unit (ICU) patients and associated with poor outcome. Therefore delirium prevention is imperative. Interventions targeting several delirium risk factors represent a promising strategy for prevention. In preparation for a stepped wedge randomized controlled trial to study the effect of a multicomponent intervention program on ICU delirium, we developed an intervention program which is aimed at delirium prevention to ultimately increase the number of delirium free days.
Australian Critical Care | 2018
Paul Rood; G.J. Huisman; H. Vermeulen; Lisette Schoonhoven; Peter Pickkers; M.H.W.A. van den Boogaard
American Journal of Critical Care | 2018
Annelies Wassenaar; Paul Rood; Danielle Boelen; Lisette Schoonhoven; Peter Pickkers; Mark van den Boogaard
Nederlands Tijdschrift voor Geneeskunde | 2017
Tianne Numan; M.H.W.A. van den Boogaard; A.M. Kampen; Paul Rood; Linda M. Peelen; Arjen J. C. Slooter