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Paula J. Grabowski

Massachusetts Institute of Technology

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Publication

Featured researches published by Paula J. Grabowski.

Trends in Biochemical Sciences | 1985

Splicing messenger RNA precursors: branch sites and lariat RNAs

Richard A. Padgett; Paula J. Grabowski; Magda M. Konarska; Phillip A. Sharp

Abstract The splicing of mRNA precursors proceeds through an unusual RNA structure: a lariat or tailed circular molecule where the 5′ end of the intervening sequence is attached to an internal residue via a 2′–5′ phosphodiester bond. The role of lariat formation and its possible significance are discussed.

Science | 1984

Lariat RNA's as intermediates and products in the splicing of messenger RNA precursors

Richard A. Padgett; Maria M. Konarska; Paula J. Grabowski; Steven F. Hardy; Phillip A. Sharp

Cell | 1985

A multicomponent complex is involved in the splicing of messenger RNA precursors

Paula J. Grabowski; Sharon R. Seiler; Phillip A. Sharp

Science | 1986

Heterogeneous nuclear ribonucleoproteins: role in RNA splicing

Y D Choi; Paula J. Grabowski; Phillip A. Sharp; Gideon Dreyfuss

Cell | 1984

Messenger RNA splicing in vitro: An excised intervening sequence and a potential intermediate

Paula J. Grabowski; Richard A. Padgett; Phillip A. Sharp

Nature | 1985

Characterization of the branch site in lariat RNAs produced by splicing of mRNA precursors

Maria M. Konarska; Paula J. Grabowski; Richard A. Padgett; Phillip A. Sharp

Science | 1986

Affinity chromatography of splicing complexes: U2, U5, and U4 + U6 small nuclear ribonucleoprotein particles in the spliceosome

Paula J. Grabowski; Phillip A. Sharp

Proceedings of the National Academy of Sciences of the United States of America | 1988

Spliceosome assembly involves the binding and release of U4 small nuclear ribonucleoprotein

Angus I. Lamond; Maria M. Konarska; Paula J. Grabowski; Phillip A. Sharp

Nature | 1984

Cofactor requirements of splicing of purified messenger RNA precursors

Stephen Hardy; Paula J. Grabowski; Richard A. Padgett; Phillip A. Sharp

Cold Spring Harbor Symposia on Quantitative Biology | 1987

Splicing of Messenger RNA Precursors

Phillip A. Sharp; M.M. Konarksa; Paula J. Grabowski; Angus I. Lamond; Robert A. Marciniak; S.R. Seiler

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Phillip A. Sharp

Massachusetts Institute of Technology

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Richard A. Padgett

Cleveland Clinic

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Maria M. Konarska

Rockefeller University

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Angus I. Lamond

University of Dundee

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C. Moore

Massachusetts Institute of Technology

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Gideon Dreyfuss

University of Pennsylvania

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M.M. Konarksa

Massachusetts Institute of Technology

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Magda M. Konarska

Massachusetts Institute of Technology

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Robert A. Marciniak

Massachusetts Institute of Technology

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S.R. Seiler

Massachusetts Institute of Technology

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