Paulo Henrique Braz

Avaliação dos indicadores de lesão miocárdica em cães com leishmaniose visceral

The aim of this study was to evaluate the laboratory indicators, electrocardiographic and cardiac histological lesions in different clinical groups of dogs with visceral leishmaniasis. Serum markers were analyzed in conjunction with the electrocardiographic tracing and heart tissue fragments of 41 naturally infected dogs which were divided into three groups: asymptomatic, oligosymptomatic and symptomatic. All animals showed increased activity in serum creatine kinase MB fraction. In the electrocardiographic tracing, low voltage complex was the most frequent conduction disorder (8/12). In the histological analysis, 75.6% of the dogs showed inflammatory reaction with predominance of linfohistiocitico infiltrates (13/31) of mild to moderate intensity and multifocal distribution. Microscopic changes identified in the myocardium were independent laboratory findings, an electrocardiographic and clinical picture presented by the studied animals. The lack of association between histopathological changes and the parameters investigated indicate the difficulty in disease identification in dogs with visceral leishmaniasis and highlights the importance of including visceral leishmaniasis in the diagnosis of heart disease especially in endemic regions to the agent.

Avaliação da resposta inflamatória sistêmica induzida por carcinoma ductal in situ em cadelas

In breast tumors, inflammatory changes are common, mainly caused by neoplasias that metastasize. This work aims to evaluate the concentration of C Reactive Protein (CRP), correlating the alterations of total proteins and albumin in dogs with ductal carcinoma in situ and to demonstrate the hematological alterations found. Thirteen dogs diagnosed with ductal carcinoma in situ were screened by cytopathological examination and confirmed by histopathology. It is concluded that CRP is an acute phase protein that rises independently of total proteins and albumin and hematological changes are of little relevance for the diagnosis of ductal carcinoma in situ.

Comportamento dos marcadores bioquímicos de injúria hepática nos cães com leishmaniose visceral

The aim of this study was to identify the changes in biochemical markers of liver damage in dogs naturally infected by Leishmania sp. according to different forms presented. Blood sample of 41 dogs were seropositive in ELISA test and positive in the immunoassay tests and lymph node parasitological were collected by venipuncture of the jugular vein and placed in tube without anticoagulant to obtain serum and measurement of total cholesterol, triglycerides, urea, alkaline phosphatase, gamma glutamyl transferase, alanine aminotransferase, total protein and albumin. Stratification was held in groups, according to clinical symptoms in asymptomatic (7/41), oligosymptomatic (15/41) and symptomatic (19/41). Hyperglobulinemia, hyperproteinemia and decreased the ratio A:G were observed in all groups, and no statistically significant difference between symptomatic animals in relation to others was observed for albumin (2.87 ± 0.45 g / dL). The average cholesterol values, alkaline phosphatase, alanine aminotransferase and gamma

Comportamento da Proteína C Reativa em vacas leiteiras, comparado ao California Mastitis Test

The objective of this study was to describe the behavior of C-reactive protein (CRP), compared to the results of the California Mastitis Test (CMT) in dairy cows. Thirty eight dairy cows were used to detect subclinical mastitis. Among these animals, 21 (75%) were positive in the CMT test and 10 (35.7%) were PCR positive. When analyzing the results by the McNemar test it was possible to conclude that the diagnostic tests have no statistical relation. It can be concluded that PCR can be used as an aid in the diagnostic interpretation for subclinical mastitis when associated with CMT.

Comparação entre a citopatologia por biopsia com agulha fina e a histopatologia no diagnóstico das neoplasias cutâneas e subcutâneas de cães

The cutaneous cancers are among the most frequently diagnosed in veterinary medicine before it is sought that the diagnosis of these tumors are fast and effective. In veterinary medicine the use of cytology as a method for diagnosis has increased. Therefore is necessary that studies demonstrate the technical efficiency so that it can be used as only tool. This study aimed to compare the diagnosis made by cytological and histological techniques. Skin and subcutaneous tumors of dogs and their neoplastic type are more easily diagnosed by cytology and are the most prevalent tumors in this animal species, attended by two veterinary hospitals in Campo Grande/MS from March 2012 to December 2013. Tumor cell samples were collected by fine needle aspiration and surgical punch of 91 dogs. The cytological results showed an efficacy of 69.69% in relation to histopathology. For differentiating between neoplastic and non-neoplastic growth, the efficiency increases to 91.91%. In order to differentiate benign from malignant tumors, it was possible to find an agreement in the order of 68.13%. The most prevalent tumors were mastocytoma, followed by lipoma, fibrosarcoma and basal cell tumor.

Assessments glucose serum, lactate, creatine kinase and aspartate aminotransferase increased mile in equine room before and after race test

This study aimed to evaluate the muscle changes and the strength of horses, Quarter Horse, athletes submitted to sprint (300 meters) with the use of serum glucose reviews, lactate, creatine kinase and aspartate aminotransferase. For the evaluation, 21 horses were used in the Quarter Horse breed, aged 2 and 4 years old, weighing approximately 500 kg, submitted to race proved short distance (300 meters). Serum aspartate aminotransferase values were measured (AST), creatine kinase (CK), lactate and glucose 15 minutes before and 15 minutes after exercise. When comparing the results using T-Student (p < 0.05), it was observed that there is a statistically significant difference when comparing the groups, it is possible to notice wear and muscle regeneration, as well as adaptation to exercise. Serum tests have demonstrated good sensitivity to monitor the physical condition of the animals before and after undergoing the short run test.