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Dive into the research topics where Pavel Zacek is active.

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Featured researches published by Pavel Zacek.


The Journal of Thoracic and Cardiovascular Surgery | 2017

Remodeling root repair with an external aortic ring annuloplasty

Emmanuel Lansac; Isabelle Di Centa; Ghassan Sleilaty; Stephanie Lejeune; Alain Berrebi; Pavel Zacek; Mathieu Debauchez

Objective: Although the remodeling technique provides the most dynamic valve‐sparing root replacement, a dilated annulus (>25 mm) is a risk factor for failure. Aortic annuloplasty aims to reduce the annulus diameter, thus increasing coaptation height to protect the repair. The results of 177 patients with remodeling and external aortic ring annuloplasty were studied. Methods: Data were collected from the Aortic Valve repair InternATiOnal Registry. Preoperative aortic insufficiency grade 3 or greater was present in 79 patients (44.7%). The valve was bicuspid in 59 patients (33.3%). External annuloplasty was performed through a homemade Dacron ring (56) or a dedicated expansible aortic ring (121). Results: Thirty‐day mortality was 2.9% (5). Mean follow‐up was 41.1 ± 36.4 months. For the whole series, freedom from valve‐related reoperation, aortic insufficiency grade 3 or greater, aortic insufficiency grade 2 or greater, and major adverse valve‐related events were 89.5%, 90.5%, 77.4%, and 86.6% at 7 years, respectively, with similar results for tricuspid and bicuspid valves. Since 2007, systematic use of calibrated expansible ring annuloplasty, followed 1 year later by systematic cusp effective height assessment, significantly increased 7‐year freedom from valve‐related reoperation, aortic insufficiency grade 3 or greater, and major adverse valve‐related events up to 99.1% ± 0.9% (P = .017), 100% (P = .026), and 96.3% ± 1.8% (P = .035), respectively, whereas freedom from aortic insufficiency grade 2 or greater remained unaffected (78.1% ± 7.6%). Calibrated annuloplasty and effective height assessment were identified as protective factors from reoperation: hazard ratio, 0.13; 95% confidence interval, 0.02‐1.06; P = .057 and hazard ratio, 0.11; 95% confidence interval, 0.01‐0.95; P = .044, respectively. Conclusions: The standardization of remodeling root repair with calibrated expansible aortic ring annuloplasty and cusp effective height assessment improves valve repair outcomes.


BJUI | 2013

Long-term survival after radical surgery for renal cell carcinoma with tumour thrombus extension into the right atrium.

Jan Dominik; Petr Moravek; Pavel Zacek; Jan Vojáček; Miroslav Brtko; Miroslav Podhola; Jaroslav Pacovsky; Jan Harrer

Whats known on the subject? and What does the study add?


Angiology | 2005

Vascular Complications of the Intra-aortic Balloon Counterpulsation:

Jiří Mand’ák; Vladimir Lonsky; Jan Dominik; Pavel Zacek

From September 1994 to December 2002, 6,274 cardiosurgery operations were performed at the Department of Cardiac Surgery, University Hospital, Hradec Králové, Czech Republic. Intraaortic balloon counterpulsation (IABP) was applied in 192 cases (3.1%). From this group of 192 counterpulsated patients 103 were successfully treated (53.6%); 89 counterpulsated patients (46.4%) died from the surgical procedure (30-day mortality rate). In 5 cases (2.6%) from the group of 192, the IABP was introduced before the operation. Ischemic changes of the limb were observed in 11 cases (5.7%). Significant bleeding occurred at the site of puncture in 6 cases (3.1%). Dissection of the femoral and iliac arteries was found in 2 patients (1.0%), perforation of the iliac artery in 1 case (0.5%). In 2 cases (1.0%) the balloon was led into the venous system. In case report No. 1 an introduction of the balloon under a sclerotic plaque of the descending aorta and iliac artery is described. In case report No. 2 a placement of the balloon in the venous bloodstream is reported.


Archive | 2010

Heart Valve Surgery

Jan Dominik; Pavel Zacek

Heart valve surgery , Heart valve surgery , کتابخانه دیجیتالی دانشگاه علوم پزشکی و خدمات درمانی شهید بهشتی


Journal of Cardiac Surgery | 2014

Valve Cuspidity: A Risk Factor for Aortic Valve Repair?

Tomas Holubec; Pavel Zacek; Mostafa Jamaliramin; Maxmilian Y. Emmert M.D.; Martin Tuna; Pavel Nedbal; Jan Dominik; Jan Harrer; Volkmar Falk; Jan Vojáček

The aim of this study was to analyze short‐ and mid‐term results after aortic valve (AV) repair with particular regard to the impact of valve cuspidity (bicuspid versus tricuspid aortic valve).


European Journal of Cardio-Thoracic Surgery | 2013

Coronéo extra-aortic annuloplasty ring could stabilize even the pulmonary autograft annulus in a Ross operation

Jan Vojáček; Jaroslav Špatenka; Tomas Holubec; Pavel Zacek

The Ross procedure is an alternative technique to mechanical prosthesis and recent evidence suggests that it is associated with improved long-term survival and quality of life. However, late pulmonary autograft failure can occur more frequently in patients with significant dilation of the aortic annulus. Here, we present a technical modification of the Ross procedure--a case report of a patient who underwent a Ross procedure in which the gross dilation of the aortic annulus was reduced by implantation of an extra-aortic Coronéo annuloplasty ring. Before discharge, we performed a multidetector computed tomography (MDCT) to verify the effect of extra-aortic annuloplasty on the geometry of the neoaortic root and particularly on the dimension of the aortic annulus. The result of the MDCT demonstrated that the ring sits in the optimal position at the level of aortoventricular base and that aortic annulus is significantly reduced.


Interactive Cardiovascular and Thoracic Surgery | 2014

Selective aortic arch perfusion enables to avoid deep hypothermic circulatory arrest for extirpation of renal cell carcinoma with tumour thrombus extension into the right atrium

Pavel Zacek; Jan Dominik; Milos Brodak; Miroslav Louda

OBJECTIVES Renal cell carcinoma with a tumour thrombus extending into the right heart chambers necessitates extensive combined urological and cardiac surgery. Maximum safety and exactness in extirpation of the caval and intracardiac thrombus is achieved under deep hypothermic circulatory arrest, at a price of its non-physiological burden and time constraints. We propose a simple surgical manoeuvre enabling selective arch perfusion allowing for a milder hypothermia and liberal interval of circulatory arrest. METHODS On a routine cardiopulmonary bypass via median sternotomy, the dissection is extended along the aortic arch to identify the origins of the supra-aortic vessels. After standard aortic cross-clamping and cardioplegic cardiac arrest at moderate hypothermia, a second cross-clamp is applied at the aortic arch beyond the left carotid artery. A selective closed aortic arch perfusion is started while the extirpation of the tumour thrombus from the right atriotomy and abdominal cavotomy is being performed under conditions of circulatory arrest. RESULTS Using selective aortic arch perfusion, successful and uncomplicated extirpation of voluminous caval and intracardiac tumour thrombi was accomplished in 3 presented patients. Unexpectedly difficult thrombus adhering to hepatic veins in 1 patient required 42 min of circulatory arrest. Postoperative courses were uneventful in all 3 patients. CONCLUSIONS Second aortic cross-clamp to start selective closed aortic arch perfusion provides excellent surgical control of the operative field over a liberal time interval during circulatory arrest under milder hypothermia.


Journal of Cardiac Surgery | 2010

Left coronary artery compression caused by a false aneurysm expansion after perforation of type A aortic dissection.

Jan Vojáček; Josef Bis; Jan Dominik; Josef Stasek; Tomas Holubec; Pavel Zacek; Jan Harrer

(J Card Surg 2010;25:72‐73)


Journal of Cardiac Surgery | 2014

One-step supraclavicular approach to the treatment of Dysphagia lusoria.

Michal Lesko; Pavel Zacek; Zdenek Belobradek; Jan Raupach; Jan Vojáček

A one‐step supraclavicular approach for the surgical treatment of the aberrant right subclavian artery is described in a case of dysphagia lusoria in a 38‐year‐old female. The approach allows for safe division of the arteria lusoria and its re‐anastomosis to the common carotid artery while the patient benefits from a mini‐invasive extrathoracic procedure. doi: 10.1111/jocs.12287 (J Card Surg 2014;29:519–522)


Journal of Cardiac Surgery | 2013

Cardiac Sarcoidosis: ISOLATEDCARDIACSARCOIDOSIS

Pavel Zacek; Nedal Omran; James Lago Chek; Lukas Krbal; Jan Vojáček; Jan Harrer

Cardiac sarcoidosis is a rare entity and may be difficult to diagnose prior to cardiac surgery. We review the imaging and diagnostic studies necessary to make the diagnosis and discuss therapeutic algorithms to manage this disease. doi: 10.1111/jocs.12163 (J Card Surg 2013;28:525–528)

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Jan Dominik

Charles University in Prague

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Jan Vojáček

Charles University in Prague

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Jan Harrer

Charles University in Prague

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Tomas Holubec

Charles University in Prague

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Zdenek Belobradek

Charles University in Prague

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Josef Stasek

Charles University in Prague

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Martin Tuna

Charles University in Prague

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Martin Vobornik

Charles University in Prague

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Tomas Holubec

Charles University in Prague

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James Lago Chek

Charles University in Prague

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