Pavo Filaković

Depresion en pacientes con alteraciones del tiroides

RESUMEN – Nuestro estudio fue realizado en un grupo de 53 mujeres con disfuncion tiroidea y 28 mujeres con depresion mayor. Empleamos la Escala de la Depresion de Hamilton, la Escala de Autoevaluacion de la Depresion de Zung y la Escala sobre la Impresion Clinica Global. Los resultados del estudio demuestran que la mayoria de los pacientes con disfuncion tiroidea se mostraron clinicamente significativos en cuanto al trastorno depresivo. Los episodios depresivos son mas frecuentes en pacientes con hipotiroidismo que en aquellos que presentan hipertiroidismo. Era menos grave en pacientes con disfuncion tiroidea que en aquellos que habian sido diagnosticados de depresion mayor unipolar. Los pacientes con hipertiroidismo tenian menos sintomas graves en cuanto a la inhibicion y los pacientes con hipotiroidismo tenian menos sintomas graves de agitacion que los pacientes con depresion mayor unipolar. Podemos concluir diciendo que los pacientes con disfuncion tiroidea presentan un riesgo potencial para los trastornos depresivos por lo que el diagnostico y tratamiento se recomienda con el fin de evitar el riesgo de la cronicidad.

Depression, Personality and Life Stress Among Women with Breast Cancer in Eastern Croatian Region

Breast cancer is the most common among women and representsthe overall leading cancer in mortality rates. There is more than million newlydiagnosed breast cancer in the world every year. Incidence of breast cancer inCroatia is 100/100 000 or 2300 women per year. Every year, in Croatia, 900women die due to this carcinoma. Breast carcinoma is mostly found in women ages45-60. As the depression rates grow higher every year it isimportant to address the fact that among women with breast cancer the depressivesymptomes or depressive disorder is three times higher. These symptomes areoften correlated with stress (various life events), personality traits, sociodemographics and course of the primary disease (breast cancer). We have conducted a research among eighty (N=80)premenopausal women (40-60 years) withdiagnosed breast cancer shortly (3-7 days) after surgical treatment. Exclusion criteria was any kind of earliermental illness or psychiatric treatment/therapy . This research was conductedon Clinic for Surgery, Department of Thoracic surgery in the Clinical HospitalCentre Osijek (Croatia) and following questionnaires were applied: Hamiltondepression rating scale; Temperament and Character Inventory and Life Change Index Scale – The Stress Test. The obtained results were showed new perspective in dealingwith this disease, especially in this eastern Croatian region, and need forinterdisciplinary approach since significantly high ratio of women showeddepressive simptomes due to negative results correlated with stress and poorsocial/family support and also with specific personality features.

EPA-1139 – Influence of personality traits on depression severity in adolescents

Introduction Recognizing the link between depression and personality traits in adolescents can alleviate identification of individual triggers for developing and diagnosing depression, treatment approach and plan as well as at-risk individuals for suicide ideation. Current studies suggest that depression is linked to several personality traits according to psychobiological model such as: harm avodiance, novelty seeking and self-directedness. Also, personality traits appear to contribute to the onest and course/severity ofdepression. Often, this is more pronounced if there are adverse social factors affectingthe overall family functioning of particular adolescent. Material and Methods Our study was conducted on the Clinical Department for Children and Adolescents during 6-month period. We included both female and male adolescentes (15 years and older) entering the psychatric treatment and diagnosed as depressive disorder according to criteria of ICD-10. Personality traits (temperament and character)were assesed with, Temperament and Character Inventory-revised’ (TCI, Cloninger) and depressive symptoms with, Beck Depression Inventory’ (BDI). The social factors were identified through the region-specific questionnaire. Conclusion Our study has shown that severity of depression correlates with specific temperament and character traits according to psychobiological model but also how adverse social factors have significant impact on presentation of depressive symptoms. It might be possible that such negative social enviroment could impact the development of specific personality traits which predispose individual for development of depression

EPA-0277 – Post-stroke depression and suicidality correlated with personality features among elderly patients

Introduction Depression may occur as a result of cerebrovascular disease in a significant subpopulation of elderly persons. Recent studies indicate a high frequency of depression in older patients with cardiovascular and cerebrovascular diseases, and the possibility of a bidirectional relationship between depression and vascular disease. Materials and methods Our research included 62 post-stroke patients above age 60 undergoing post-stroke treatment in department of Neurology and 30 elderly patients who had suffered stroke one year ago and underwent psychiatric treatment. Each patient were given scales for assessment of depressive symptomes (Hamilton depression rating scale HAM-D), suicidality (Columbia suicide severity rating scale CSSR-S) and the list for assessment of borderline personality symptoms (Borderline Symptom List BSL) with examination of mental state (MMSE). These scales were given prior to antidepressant treatment and two weeks following the treatment. Results The obtained results shown positive correlation of depressive symptoms, suidical ideation and cognitive impairment in the group of post-stroke patients in psychiatric (with higher positive correlation in women). While in the group of elderly patients in psychiatric treatment (> than 1 year) the depressive symptoms were highly correlated with positive bordeline personality features and these specific personality features were highly correlated with suicidal ideation. Conclusion Our research showed how depressive symptoms are variable and highly correlated with personality features along with cognitive functioning. However, suicidal ideation was more correlated with specific personality features than depression itself. We have also concluded that concept of suicidality in the elderly seems unjustifiable neglected and should be more vigorously identified.