Pedro Villablanca Spinetto

USE OF DUAL ANTIPLATELET VERSUS SINGLE ANTIPLATELET THERAPY FOR PREVENTION OF RECURRENT ISCHEMIC STROKE: META-ANALYSIS OF RANDOMIZED CONTROLLED TRIALS

Antiplatelet agents are used for secondary prevention in patients with ischemic stroke or transient ischemic attack. Emerging studies suggest that early administration of dual antiplatelet therapy (DAPT) may be better than single antiplatelet therapy for the prevention of recurrent ischemic stroke,

PERCUTANEOUS RENAL DENERVATION FOR RESISTANT HYPERTENSION: AN UPDATED META-ANALYSIS OF RANDOMIZED CONTROLLED TRIALS

Background: Percutaneous renal denervation (RDN) was heralded as a novel approach to treat resistant hypertension (RH), however evidence supporting its efficacy is conflicting. We therefore conducted an updated meta-analysis of randomized controlled trials (RCTs) evaluating the effect of RDN on

SUBSTITUTION OF LEFT VENTRICULAR OUTFLOW TRACT DIAMETER WITH BODY SURFACE AREA

Measurement of the left ventricular outflow tract (LVOT) diameter is a key parameter in the calculation of stroke volume, aortic valve area and mitral valve area on transthoracic echocardiography (TTE). We had observed that the numeric value for body surface area (BSA) reported in m2 frequently

TRANSCATHETER AORTIC VALVE REPLACEMENT VERSUS SURGICAL AORTIC VALVE REPLACEMENT FOR SEVERE AORTIC STENOSIS: META-ANALYSIS OF RANDOMIZED CONTROLLED TRIALS

Transcatheter aortic valve replacement (TAVR) is an alternative to surgical aortic-valve replacement (SAVR) for high-risk patients with severe aortic stenosis (AS). Our objective was to evaluate the efficacy and safety of TAVR compared with SAVR in high-risk patients with AS. We conducted

SHORT DURATION VERSUS 1-YEAR DUAL ANTIPLATELET THERAPY AFTER DRUG-ELUTING STENTS IMPLANTATION: SYSTEMATIC REVIEW AND META-ANALYSIS OF RANDOMIZED CONTROLLED TRIALS

The benefits of 1-year of dual antiplatelet therapy (DAPT) as compared with short-term (≤ 6 months), in patients undergoing percutaneous coronary intervention (PCI) after drug-eluting stents (DES) remains controversial. We performed a meta-analysis of 1-year versus short-term duration DAPT in

THERAPEUTIC HYPOTHERMIA FOR MYOCARDIAL PROTECTION IN ST ELEVATION MYOCARDIAL INFARCTION: A SYSTEMATIC REVIEW AND META-ANALYSIS OF RANDOMIZED CONTROL TRIALS

Studies have suggested that therapeutic hypothermia (TH) in acute ST elevation myocardial infarction (STEMI) might be beneficial. The supportive evidence showing beneficial outcomes is limited. We performed a meta-analysis of randomized controlled trials (RCT) to assess the efficacy and safety of TH

CULPRIT VERSUS MULTIVESSEL 1-STAGE PERCUTANEOUS CORONARY INTERVENTION IN ST ELEVATION MYOCARDIAL INFARCTION: A SYSTEMATIC REVIEW AND META-ANALYSIS OF RANDOMIZED CONTROL TRIALS

Studies employing primary percutaneous intervention (PCI) in patients with ST segment elevation myocardial infarction (STEMI) have shown discordant results regarding the relative benefits of treating the culprit lesion only vs all significant stenosis. We performed a meta-analysis comparing PCI of

LEFT ATRIAL APPENDAGE OCCLUSION DEVICE AND NOVEL ORAL ANTICOAGULANTS VERSUS WARFARIN FOR STROKE PREVENTION IN NON-VALVULAR ATRIAL FIBRILLATION: A SYSTEMATIC REVIEW AND META-ANALYSIS OF RANDOMIZED CONTROL TRIALS

Different strategies have been evaluated for stroke prevention in patients with non-valvular atrial fibrillation (NVAF). We sought to evaluate the efficacy and safety of different approaches compared to standard therapy with warfarin. We conducted electronic database searches of phase III

Coronary Artery Spasm: Is ST Elevation Key for Diagnosis?

Coronary vasospasm is uncommon in pregnancy and the post-partum period. We present a very rare case about an acute coronary vasospasm in a 36-year-old woman, 2 weeks postpartum. The coronary arteriograms showed a coronary vasospasm in the distal left anterior descending and circumflex coronary arteries. EKG presentation was atypical, with T-wave inversions in leads I, aVl, V2-V6. To our knowledge, this is the first case with a welldocumented coronary artery vasospasm in a postpartum woman, without the classic ST elevation on EKG. Management should follow the usual principles of care for acute coronary vasospasm.