Pengfei Song

Preparation of low-molecular-weight chitosan derivative zinc complexes and their effect on the growth of liver cancer cells in vitro

Low-molecular-weight (LMW) chitosan salicylaldehyde Schiff-base and its zinc(II) complexes were synthesized and characterized by Fourier transform-infrared (FT-IR) spectra, transmission electron microscopy (TEM), dynamic light scattering (DLS), gel permeation chromatography-multiangle laser light scattering (GPC-MALLS), and elemental analysis. The results of electrophoretic analysis suggest that the Zn complexes bound to DNA by means of electrostatic interactions and intercalation. The effect of the Zn complexes on the growth of SMMC-7721 liver cancer cells was investigated by sulforhodamine B assay in vitro. The results reveal that the growth of liver cancer cells was inhibited by LMW-chitosan and their Zn complexes. The inhibition rate of the Zn complexes was higher than that of LMW-chitosan ligand. The LMW-chitosan Schiff-base Zn complex exhibited higher anticancer activity than the LMW-chitosan Zn complex. Combining LMW-chitosan with Schiff-base and Zn improved its anticancer activity, which we ascribe to the synergistic effect between the chitosan matrix and the planar construction of the Zn complexes.

Keratin films from chicken feathers for controlled drug release.

Abstract summaryDuring the past two decades significant advances have been made in the development of biomaterials for biomedical applications, especially biomaterials based on natural polymers. In this paper, we report the preparation of protein films for controlled drug release applications. This

A facile fabrication of amphiphilic Janus and hollow latex particles by controlling multistage emulsion polymerization

In this paper, we found that morphology controllable compound latex particles could be prepared by controlling the multistage emulsion polymerization. Influences of the content of methacrylic acid (MAA) on preparing the hydrophilic cores and the particles were investigated with the observation of dynamic light scattering (DLS) and transmission electron microscope (TEM) results. The acorn-like latex particles were synthesized by partially encapsulated with hydrophobic polystyrene (PSt)-layer. With adding moderate polarity polymethylmethacrylate (PMMA) interlayer, the hydrophilic cores could be fully encapsulated by the hydrophobic PSt-layer, and the core-shell structure formed. After alkali treatment, the acorn-like and core-shell latex particles evolved into amphiphilic Janus and hollow latex particles, respectively. The morphology of latex particles was investigated by TEM, and the forming mechanism of amphiphilic Janus and hollow latex particles was proposed.

Reutilization of discarded biomass for preparing functional polymer materials

Biomass is abundant and recyclable on the earth, which has been assigned numerous roles to human beings. However, over the past decades, accompanying with the rapid expansion of man-made materials, such as alloy, plastic, synthetic rubber and fiber, a great number of natural materials had been neglected and abandoned, such as straw, which cause a waste of resource and environmental pollution. In this review, based on introducing sources of discarded biomass, the main composition and polymer chains in discarded biomass materials, the traditional treatment and novel approach for reutilization of discarded biomass were summarized. The discarded biomass mainly come from plant wastes generated in the process of agriculture and forestry production and manufacturing processes, animal wastes generated in the process of animal husbandry and fishery production as well as the residual wastes produced in the process of food processing and rural living garbage. Compared with the traditional treatment including burning, landfill, feeding and fertilizer, the novel approach for reutilization of discarded biomass principally allotted to energy, ecology and polymer materials. The prepared functional materials covered in composite materials, biopolymer based adsorbent and flocculant, carrier materials, energy materials, smart polymer materials for medical and other intelligent polymer materials, which can effectively serve the environmental management and human life, such as wastewater treatment, catalyst, new energy, tissue engineering, drug controlled release, and coating. To sum up, the renewable and biodegradable discarded biomass resources play a vital role in the sustainable development of human society, as well as will be put more emphases in the future.

Bovine Serum Albumin Metal Complexes for Mimic of SOD

AbstractSuperoxide anion radical (O2∙−

Fabrication of dual-sensitive keratin-based polymer hydrogels and their controllable release behaviors

_{2}^{\bullet -}

Poly(ionic liquid)-based nanogels and their reversible photo-mediated association and dissociation

) is a noxious reactive oxygen species (ROS). Transition metal ion complexes have been generally used as antioxidants to eliminate ROS. In this work, a neoteric water-soluble biopolymer metal complex (BSA-M) was prepared by conjugating the soluble biopolymer bovine serum albumin (BSA) with three transition metal ions (M, M =Cu, Co, Mn). The binding mode and ratio of metal ions bound to albumin were investigated. The BSA-M complexes were characterized by UV-Vis, circular dichroism (CD) spectra and polyacrylamide gel electrophoresis (PAGE). BSA served as polymer scaffold and the metal complex functioned as the catalytic active center. The results demonstrated that the structure of BSA remained unchanged when the binding ratio of transition metal ion complex to BSA was 5:1. Furthermore, the scavenging superoxide anion free radical (O2∙−

Polypyrrole nanocomposites doped with functional ionic liquids for high performance supercapacitors

_{2}^{\bullet -}

Itaconic copolymer modified loess for high-efficiently removing copper ions from wastewater

) activity of biopolymer-metal complexes were determined by nitroblue tetrazolium light reduction assay method. The antioxidant capacity of BSA-M has markedly increased. The conjugated BSA-M (M=Cu, Mn) showed preeminent scavenging activity for O2∙−

Preparation of multi-responsive amphiphilic particles by one-step soapless emulsion polymerization

_{2}^{\bullet -}