Per-Ake Pernemalm

Reaction of Nα-acetyl-DL-tryptophan amide with D-xylose or D-glucose in acidic solution

Abstract The reaction of N α - acetyl - dl )- tryptophan amide (a model for proteinbound tryptophan) with either d - xylose or d - glucose in acidic solution at 75 or 100°C gave the respective N α - acetyl -1-(β- d - glycopyranosyl )- dl - tryptophan amides as the main products in 10–20% yield. These results indicate that the indole nitrogen of protein-bound tryptophan may react with reducing carbohydrates during acid hydrolysis of proteins or, to a lesser extent, during food processing in acidic conditions.

A High Performance Preparative Procedure for the Isolation of Degradation Products from D-Xylose

Abstract An improved method for the preparative isolation of 3,8 dihydroxy-2-methylchromone, formed by degradation of D-xylose at 100°C is presented. From the ethyl acetate extractable part of the reaction mixture the chromone was isolated by preparative HPLC in less than one hour using a highly cross-linked dextran gel.