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Peter L. Barker

Genentech

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Publication

Featured researches published by Peter L. Barker.

Tetrahedron Letters | 1994

Mono-N-alkylation of anthranilamides via quinazolinones. An efficient synthesis of G5598, a benzodiazepine dione gpIIbIIIa antagonist

Rob Webb; Peter L. Barker; Mark Baier; Mark Reynolds; Kirk Robarge; Brent Blackburn; Maureen H. Tischler; Kenneth J. Weese

Abstract The mono-N-alkylation of an anthranilamide derivative via the reductive ring opening of a quinazolinone precursor, enables the synthesis of benzodiazepine dione derivative G5598, a potent inhibitor of the in vitro binding of GpIIbIIIa to fibrinogen.

Journal of Medicinal Chemistry | 1992

Cyclic RGD peptide analogues as antiplatelet antithrombotics

Peter L. Barker; Sherron Bullens; Stuart Bunting; Daniel J. Burdick; Kathryn S. Chan; Tracy Deisher; Charles Eigenbrot; Thomas Gadek; Robin Gantzos

Archive | 1995

Nonpeptidyl integrin inhibitors having specificity for the GPIIb IIIa receptor

Brent Blackburn; Peter L. Barker; Thomas Gadek; Robert S. McDowell; Lawrence McGee; Todd C. Somers; Rob Webb; Kirk Robarge

Archive | 1990

Small cyclic platelet aggregation inhibitors

Peter L. Barker; John Burnier; Thomas Gadek; Eugene D. Thorsett

Archive | 1992

Nonpeptidyl platelet aggregation inhibitors having specificity for the GPIIb III.sub. receptor

Brent Blackburn; Robert Mcdowell; Thomas Gadek; Peter L. Barker; Lawrence McGee; Rob Webb

Archive | 1991

CYCLIC PEPTIDES CONTAINING Arg-Gly-Asp FLANKED BY PROLINE

Peter L. Barker; John Burnier; Robert A. Lazarus

Archive | 1989

Cyclized peptides and their use as platelet aggregation inhibitors

Peter L. Barker; John Burnier; Eugene D. Thorsett

Archive | 1995

Nonpeptidyl integrin inhibitors having specificity for the GPIIb IIIa

Brent Blackburn; Peter L. Barker; Thomas Gadek; Robert Mcdowell; Lawrence McGee; Todd C. Somers; Rob Webb; Kirk Robarge

Advances in Medicinal Chemistry | 1995

Antiplatelet and antithrombotic agents: From viper venom proteins, to peptides and peptidomimetics, to small organic molecules

Peter L. Barker; Rob Webb

Archive | 1992

Small cyclic RGD containing peptides as potent inhibitors of platelet aggregation

John Burnier; Peter L. Barker; Sherron Bullens; Stuart Bunting; Daniel J. Burdick; Kathryn S. Chan; Thomas Gadek; Michael T. Lipari; Craig D. Muir; Mary A. Napier; Robert M. Pitti; Clifford Quan; Mark S. Stanley; Martin Struble; Jeffrey Tom

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Thomas Gadek

Genentech

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John Burnier

Genentech

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Rob Webb

Genentech

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Brent Blackburn

Genentech

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Eugene D. Thorsett

Genentech

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Kirk Robarge

Genentech

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Lawrence McGee

Genentech

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Robert Mcdowell

University of California

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Todd C. Somers

Genentech

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Daniel J. Burdick

Genentech

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