Petro P. Onys'ko

N-(α-Hydroxytrihaloethyl)carbamates in synthesis of phosphorus analogs of trihaloalanine derivatives

GRAPHICAL ABSTRACT ABSTRACT Convenient synthetic approaches for phosphorus analogs of trifluoro- and trichloroalanine derivatives were developed based on readily accessible N-(α-hydroxytrihaloethyl)carbamates.

A new reaction of vicinal sulfonyliminocarboxylates with phosphites

Abstract The reaction of alkyl trifluoro(organylsulfonylimino)propionates with phosphites occurs with NC transfer of the RSO2 group and leads to sulfonyl-substituted trifluoroalanine derivatives. The novel rearrangement is interpreted as cheletropic 1,4-cycloaddition of the phosphite and subsequent 1,2-shift of the sulfonyl group in the intermediate cyclic phosphorane.

Phosphorylation of Imino Analogs of α -Halocarbonyl Compounds

Phosphorylation of the α-haloimines leads mainly to C- or N-phosphorylated compounds as the final products, and selectivity being dependent on the type of halogen, substituents at the imine carbon and nitrogen atoms, and on the nature of phosphorus regeant. Variety of transformations is connected with rearrangements accompanied by umpolung of C- and N-center of imine function, possible participation of C═N bond, halogen atoms or N-substituents, in ractions involving the Hal-C─C═N skeleton.

N-Acyl-and N-Phosphorylpolyhalogenoalkyl-Imidolylphosphonates: Synthesis and Reactions

Abstract Methods of synthesis of polyhalogenoalkylimidoyl phosphonates, the phosphorus analogs of a well-known and widely used acylimines of polyhalogenocarbonyl compounds, have been developed.