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Petrônio Filgueiras de Athayde Filho

Federal University of Paraíba

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Acta Pharmaceutica | 2014

Synthesis and preliminary ex vivo evaluation of the spasmolytic activity of 1,3-thiazolium- and 1,3,4-thiadiazolium-5-methylthio- and 5-thioacetate derivatives.

José Alixandre de Sousa Luis; Thiago Mendonça de Aquino; Bruno Freitas Lira; Petrônio Filgueiras de Athayde Filho; Marcus T. Scotti; Luciana Scotti; Ricardo Olímpio de Moura; Francisco Jaime Bezerra Mendonça Junior

Abstract Seven new compounds have been synthetized in satisfactory yields (51-78 %) through the treatment of mesoionic 1,3-thiazolium-5-thiolate (4a-d) and 1,3,4-thiadiazolium- 5-thiolate (10a,b) with chloroacetic acid or methyl iodide: 1,3,4-thiadiazolium-5-methylthio- (11) and 5-thioacetate (12). The structure of the title compounds was elucidated by elemental analysis, IR, 1H and 13C NMR spectroscopy. The newly synthesized compounds 5a, 6a, 11 and 12 were evaluated for their ex vivo spasmolytic potential on four isolated smooth muscles (rat aorta and uterus, guinea pig ileum and trachea) and compared with scopolamine. Some of the compounds exhibited potent spasmolytic activity equal to or stronger than scopolamine

Journal of Thermal Analysis and Calorimetry | 2004

KINETICS OF DECOMPOSITION OF ALKYLAMMONIUM SALTS

H. R. C. Ouriques; M. F. S. Trindade; M. M. Conceiçăo; Shiva Prasad; Petrônio Filgueiras de Athayde Filho; A. G. Souza

Journal of Thermal Analysis and Calorimetry | 2005

Thermogravimetric investigations on the thermal degradation of bixin, derived from the seeds of annatto (Bixa Orellana L.)

Marta C. D. Silva; J. R. Botelho; M. M. Conceiçăo; B. F. Lira; Monyque A. Coutinho; A. F. Dias; A. G. Souza; Petrônio Filgueiras de Athayde Filho

Journal of Thermal Analysis and Calorimetry | 2004

Kinetic and thermodynamic parameters of the thermal decomposition of zinc(ii) dialkyldithiocarbamate complexes

M. C. D. Silva; M. M. Conceiçăo; M. F. S. Trindade; A. G. Souza; Carla Pinheiro; J.C. Machado; Petrônio Filgueiras de Athayde Filho

Journal of Alloys and Compounds | 2010

Synthesis and characterization of nanocomplexes of Eu(III) and Er(III) coordinate with 2(4-clorophenil)-3-phenyl-1,3,4-thiadiazoleo-5-tiolate mesoionic

Railda Shelsea Taveira Rocha do Nascimento; Crislene Rodrigues da Silva Morais; Hélio Lucena Lira; Soraya Alves de Morais; Petrônio Filgueiras de Athayde Filho; Luciana de Figueiredo Lopes Lucena; A. G. Souza; Gabriela Brasileiro Campos

Arkivoc | 2004

Synthesis and complete assignments of 1H and 13C NMR spectra of mesoionic 1,3-thiazolium-2 thiolates

Bruno Freitas Lira; Joseph A. Miller; Alfredo M. Simas; Petrônio Filgueiras de Athayde Filho; Aderson de Farias Dias; Ricardo Oliveira Silva; Vicente Carlos de Oliveira

Journal of Alloys and Compounds | 2010

Influence of the aromatic substitutes in the thermal and kinetic behavior of mesoionic compounds of the 1,3-thiazole-5-tiolate system

Soraya Alves de Morais; Crislene Rodrigues da Silva Morais; Petrônio Filgueiras de Athayde Filho; Bruno Freitas Lira; Marcos Antonio feitosa de Souza

Journal of Thermal Analysis and Calorimetry | 2009

A kinetic study of the thermal decomposition of mesoionic compounds within scope of its application in nonlinear optical devices

Soraya Alves de Morais; Crislene Rodrigues da Silva Morais; Petrônio Filgueiras de Athayde Filho; B. Freitas Lira; Railda Shelsea Taveira Rocha do Nascimento

Revista Eletrônica de Farmácia | 2013

ESTUDO ANTIFÚNGICO DE NOVAS IMIDAS PLANEJADAS A PARTIR DO SAFROL

José Alixandre de Sousa Luis; Normando Alexandre da Silva Costa; Cristiane Cosmo da Silva; Petrônio Filgueiras de Athayde Filho

Archive | 2011

Heterogeneous catalyst of calcined silica/potassium (STPC)

Juliana Kelly Dionísio Souza; Daniella I. de O. Silva; Bruno Freitas Lira; Maria Cláudia Rodrigues Brandão; José Maria Barbosa Filho; Petrônio Filgueiras de Athayde Filho; Helivaldo Souza; Juliana Andreza Figueirôa; Ieda M. G. Santos

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A. G. Souza

Federal University of Paraíba

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Bruno Freitas Lira

Federal University of Paraíba

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Crislene Rodrigues da Silva Morais

Federal University of Campina Grande

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M. M. Conceiçăo

Federal University of Paraíba

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Soraya Alves de Morais

Federal University of Paraíba

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José Alixandre de Sousa Luis

Federal University of Campina Grande

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M. F. S. Trindade

Federal University of Paraíba

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Railda Shelsea Taveira Rocha do Nascimento

Federal University of Campina Grande

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Joseph A. Miller

Purdue University

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A. F. Dias

Federal University of Paraíba

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