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Philip M. Carabateas

Rensselaer Polytechnic Institute

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Featured researches published by Philip M. Carabateas.

Journal of Medicinal Chemistry | 1977

Antiviral activity of some beta-diketones. 2. Aryloxy alkyl diketones. In vitro activity against both RNA and DNA viruses.

Guy D. Diana; Philip M. Carabateas; Robert E. Johnson; Gordon L. Williams; Francis Pancic; Joseph C. Collins

The synthesis and in vitro antiviral evaluation of a series of substituted benzyl beta-diketones are described. The introduction of a styryl group onto the phenyl ring enhanced activity against herpesvirus type 2. The 4-methoxystyryl homologue 8 was evaluated extensively in vitro and was found to be effective against both RNA and DNA viruses. Compound 8 was evaluated in the mouse vagina against herpes simplex type 1 and produced a significant increase in survival rate as well as in survival time.

Bioorganic & Medicinal Chemistry Letters | 1996

C-ATTACHED AMINOALKYLINDOLES : POTENT CANNABINOID MIMETICS

Thomas E. D'Ambra; Michael Eissenstat; Jeffrey W. Abt; James H. Ackerman; Edward R. Bacon; Malcolm R. Bell; Philip M. Carabateas; Kurt A. Josef; Virendra Kumar; John D. Weaver; Renee Arnold; Frances M. Casiano; Susan M. Chippari; Dean A. Haycock; Joan E. Kuster; Daniel Luttinger; Joan I. Stevenson; Susan Jean Ward; W.Adam G. Hill; Atmaram D. Khanolkar; Alexandros Makriyannis

Abstract Aminoalkylindoles (AAIs) with potent cannabinoid agonist activity have been synthesized where the aminoalkyl chain is attached to the indole ring via a carbon atom of the cyclic amine.

Archive | 1971

1,4-DIHYDRO-4-OXO-7-PYRIDYL-3-QUINOLINE-CARBOXYLIC ACID DERIVATIVES

Philip M. Carabateas; George Y. Lesher

Journal of Medicinal Chemistry | 1993

3-Quinolinecarboxamides. A series of novel orally-active antiherpetic agents

Mark P. Wentland; Robert B. Perni; Peter Hans Dorff; R. Pauline Brundage; Michael J. Castaldi; Thomas R. Bailey; Philip M. Carabateas; Edward R. Bacon; Dorothy C. Young

Archive | 1991

3-arylcarbonyl-1-(c-attached-n-heteryl)-1h-indoles

Thomas E. D'Ambra; Edward R. Bacon; Malcolm R. Bell; Philip M. Carabateas; Michael Eissenstat; Virendra Kumar; John P. Mallamo; Susan Jean Ward

Journal of Medicinal Chemistry | 1994

2,6-Disubstituted aryl carboxylic acids, leaving groups par excellence for benzisothiazolone inhibitors of human leukocyte elastase

Chakrapani Subramanyam; Malcolm R. Bell; Philip M. Carabateas; John J. Court; John A. Dority; Edward Ferguson; Robert J. Gordon; Dennis J. Hlasta; Kumar; Manohar Saindane

Journal of Medicinal Chemistry | 1995

Orally bioavailable benzisothiazolone inhibitors of human leukocyte elastase.

Dennis J. Hlasta; Chakrapani Subramanyam; Malcolm R. Bell; Philip M. Carabateas; John J. Court; Ranjit C. Desai; Drozd Ml; Eickhoff Wm; Edward Ferguson; Robert J. Gordon

Journal of Medicinal Chemistry | 1992

Antirhinoviral activity of heterocyclic analogs of Win 54954

Thomas R. Bailey; Guy D. Diana; Paul Kowalczyk; Vahan Akullian; Michael A. Eissenstat; David Cutcliffe; John P. Mallamo; Philip M. Carabateas; Daniel C. Pevear

Journal of Medicinal Chemistry | 1995

Synthesis and antibacterial activity of some novel 1-substituted 1,4-dihydro-4-oxo-7-pyridinyl-3-quinolinecarboxylic acids. Potent antistaphylococcal agents.

Michael Reuman; Sol J. Daum; Baldev Singh; Mark P. Wentland; Robert B. Perni; Patrick O. Pennock; Philip M. Carabateas; Monte D. Gruett; Manohar Saindane; Peter Hans Dorff; Susan A. Coughlin; David M. Sedlock; James B. Rake; George Y. Lesher

Archive | 1991

3-Arylcarbonyl-1H-indoles useful as therapeutic agents

Thomas E. D'Ambra; Edward R. Bacon; Malcolm R. Bell; Philip M. Carabateas; Michael Eissenstat; Virendra Kumar; John P. Mallamo; Susan Jean Ward

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Guy D. Diana

Rensselaer Polytechnic Institute

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John P. Mallamo

Eastman Kodak Company

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George Y. Lesher

Rensselaer Polytechnic Institute

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Malcolm R. Bell

Rensselaer Polytechnic Institute

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Gordon L. Williams

Rensselaer Polytechnic Institute

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Virendra Kumar

Banaras Hindu University

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Michael Eissenstat

Rensselaer Polytechnic Institute

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Susan Jean Ward

Rensselaer Polytechnic Institute

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Edward R. Bacon

Nycomed

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Chakrapani Subramanyam

Pfizer

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