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Dive into the research topics where Pierre Alexandre Driguez is active.

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Featured researches published by Pierre Alexandre Driguez.


Bioorganic & Medicinal Chemistry Letters | 1997

Synthesis and biological activity of a new anti-factor Xa pentasaccharide with a C-interglycosidic bond

Arnim Helmboldt; Maurice Petitou; Jean-Maurice Mallet; Jean-Pascal Herault; Jean-Claude Lormeau; Pierre Alexandre Driguez; Jean-Marc Herbert; Pierre Sinaÿ

Abstract A mixed synthetic C, O-pentasaccharide 17 has been synthesized and shown to display an anti-factor Xa activity similar to that of the corresponding O-pentasaccharide 18. 17 represents the first example of a synthetic C-oligosaccharidic mimetic eliciting a significant biological response.


Archive | 1999

Synthetic polysaccharides, their method of production and pharmaceutical compositions containing same

Johannes Basten; Cornelia Dreef-Tromp; Pierre Alexandre Driguez; Philippe Duchaussoy; Jean Marc Herbert; Maurice Petitou; Constant A. A. van Boeckel


Archive | 1997

Synthetic polysaccharides, preparation method therefor and pharmaceutical compositions containing same

Pierre Alexandre Driguez; Philippe Duchaussoy; Jean Marc Herbert; Maurice Petitou; Constant A. A. van Boeckel; Peter Grootenhuis; Johannes Basten; Cornelia Dreef-Tromp


Archive | 2005

Azasugar derivatives, heparanase inhibitors, method for preparing same, compositions containing same, use thereof

Maurice Petitou; Pierre Alexandre Driguez


Archive | 1997

Polysaccharides synthetiques, procede pour leur preparation et compositions pharmaceutiques les contenant

Johannes Basten; Cornelia Dreef-Tromp; Pierre Alexandre Driguez; Philippe Duchaussoy; Peter D. J. Grootenhuis; Jean-Marc Herbert; Maurice Petitou; Boeckel Constant Adriaan A Van


publisher | None

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Archive | 2013

BIOTINYLATED POLYSACCHARIDES HAVING AN ANTITHROMBOTIC ACTIVITY AND IMPROVED METABOLIC STABILITY

Marc Bianciotto; Pierre Alexandre Driguez; Phillippe Duchaussoy; Gilbert Lassalle; Pierrick Le-Dref; Jean-Christophe Thiery; Patrick Trouilleux


Archive | 2012

FGF receptor-activating N-acyl octasaccharides, preparation thereof, and therapeutic use thereof

Pierre Alexandre Driguez; Philippe Duchaussoy; Pierre Fons; Corentin Herbert; Gilbert Lassalle


Archive | 2011

Polysaccharides biotinyles a activite antithrombotique et presentant une stabilite metabolique amelioree

Marc Bianciotto; Pierre Alexandre Driguez; Philippe Duchaussoy; Gilbert Lassalle; Pierrick Le-Dref; Jean-Christophe Thiery; Patrick Trouilleux


Journal of Biological Chemistry | 2010

Influence of Heparin Mimetics on Assembly of the FGF{middle dot}FGFR4 Signaling Complex

Krishna Saxena; Ulrich Schieborr; Oliver Anderka; Elke Duchardt-Ferner; Bettina Elshorst; Santosh Lakshmi Gande; Julia Janzon; Denis Kudlinzki; Sridhar Sreeramulu; Matthias K. Dreyer; Karl Ulrich Wendt; Christopher J. Herbert; Philippe Duchaussoy; Marc Bianciotto; Pierre Alexandre Driguez; Gilbert Lassalle; Pierre Savi; Moosa Mohammadi; Françoise Bono; Harald Schwalbe

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Maurice Petitou

École Normale Supérieure

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Maurice Petitou

École Normale Supérieure

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