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Latest external collaboration on country level. Dive into details by clicking on the dots.
Publication
Featured researches published by Pierre Tessier.
Bioorganic & Medicinal Chemistry Letters | 2009
Pierre Tessier; David Smil; Amal Wahhab; Silvana Leit; Jubrail Rahil; Zuomei Li; Robert Deziel; Jeffrey M. Besterman
We have identified a series of diphenylmethylene hydroxamic acids as novel and selective HDAC class IIa inhibitors. The original hit, N-hydroxy-2,2-diphenylacetamide (6), has sub-micromolar class IIa HDAC inhibitory activity, while the rigidified oxygen analogue, N-hydroxy-9H-xanthene-9-carboxamide (13), is slightly more selective for HDAC7 with an IC(50) of 0.05muM. Substitution of 6 allows for the modulation of selectivity and potency amongst the class IIa HDAC isotypes.
Journal of Medicinal Chemistry | 2007
Oscar Moradei; Tammy C. Mallais; Sylvie Frechette; Isabelle Paquin; Pierre Tessier; Silvana Leit; Marielle Fournel; Claire Bonfils; Marie-Claude Trachy-Bourget; Jianhong Liu; Theresa P. Yan; Aihua Lu; Jubrail Rahil; James C. Wang; Sylvain Lefebvre; Zuomei Li; and Arkadii F. Vaisburg; Jeffrey M. Besterman
Archive | 2007
Oscar Moradei; Isabelle Paquin; Sylvie Frechette; Tammy C. Mallais; Simon Roy; Roger Machaalani; Arkadii Vaisburg; Jeffrey M. Besterman; Pierre Tessier; John Mancuso; David Smil; Silvana Leit; Robert Deziel
Archive | 2006
Silvana Leit; Amal Wahhab; Martin Allan; David Smil; Pierre Tessier; Robert Deziel; Yves Andre Chantigny
Archive | 2014
デジール、ロバート; Deziel Robert; リート、シルヴァナ; Silvana Leit; ボリュー、パトリック; Beaulieu Patrick; シャンティグニー、イブ、アンドレ; Andre Chantigny Yves; マンクーゾ、ジョン; Mancuso John; テッシェ、ピエール; Pierre Tessier; シャピロ、ギデオン; Shapiro Gideon; チェスウォース、リチャード; Chesworth Richard; スミル、デイビッド; Smil David
Archive | 2013
Robert Deziel; Silvana Leit; Patrick Beaulieu; Yves Andre Chantigny; John Mancuso; Pierre Tessier; Gideon Shapiro; Richard Chesworth; David Smil
Archive | 2007
Oscar Moradei; Isabelle Paquin; Sylvie Frechette; Tammy C. Mallais; Simon Roy; Roger Machaalani; Arkadii Vaisburg; Jeffrey M. Besterman; Pierre Tessier; John Mancuso; David Smil; Silvana Leit; Robert Deziel
Archive | 2007
Robert Deziel; Silvana Leit; Patrick Beaulieu; Yves Andre Chantigny; John Mancuso; Pierre Tessier; Gideon Shapiro; Richard Chesworth; David Smil
Archive | 2007
Robert Deziel; Silvana Leit; Patrick Beaulieu; Yves Andre Chantigny; John Mancuso; Pierre Tessier; Gideon Shapiro; Richard Chesworth; David Smil
Archive | 2007
Robert Deziel; Silvana Leit; Patrick Beaulieu; Yves Andre Chantigny; John Mancuso; Pierre Tessier; Gideon Shapiro; Richard Chesworth; David Smil
