Piet Bergveld

Micro Total Analysis Systems 2000 : Proceedings of the µTAS 2000 Symposium, held in Enschede, The Netherlands, 14–18 May 2000

Flow Based Systems. Cell Analysis. Microtechnology and Microreactors. Microchemistry. Posters. Microfluidics I. Separation Systems. Applications. Single Molecule and Single Cell Analysis. Posters. High-Throughput Experimentation. DNA Analysis. Posters. Microfluidics II. New Concepts. Posters. Authors Index. Subject Index.

On the integration of a microdialysis-based /spl mu/TAS with calibration facility on a silicon-glass sandwich

The integration is discussed of all parts of a microdialysis-based micro Total Analysis System or /spl mu/TAS. In particular a microdialysis probe, a potentiometric and amperometric ion- and enzyme sensor and a calibration dosing pump have been developed separately using different precision machining techniques. By modifying and adapting these parts they can be realized in one generic technology consisting of a stack of a silicon and a glass wafer. The silicon wafer contains the double lumen microdialysis probe connections, a dosing pump chamber with meander formed cavities containing the calibration solutions and small cavities for both the potentiometric and amperometric sensor. The glass wafer contains all the electrical contacts and wires for the sensors, the pump and Interconnections. Both wafers are anodically bonded to each other, yielding a hermetically sealed liquid handling system.

A Temperature Controlled Micro Valve for Biomedical Applications Using a Temperature Sensitive Hydrogel

The fabrication and characterization results of a temperature sensitive hydrogel micro valve based on the polymer N-isopropylacrylamide is presented. The hydrogel actuator was fabricated by in-situ polymerization using standard UV photolithography. The valve was opened and closed by applying a temperature change from 16 to 30°C. Potential uses for the valves include skin triggered valves for biomedical micro devices.