Piotr Dybowski

A general and stereoselective method for synthesis of tri- and tetrasubstituted alkenes

A convenient, general and stereoselective synthesis of trisubstituted alkenes and tetrasubstituted alkenes containing a cyanide function as well as trisubstituted episulphides have been elaborated. Methodology described for the preparation of these compounds is based on the corresponding readily available selenophosphates 1 and thiophosphates 2.

A general one-pot synthesis of vinyl-thiiranes and conjugated dienes

Abstract The first general synthesis of vinyl-thiiranes 5 and an efficient preparation of conjugated dienes 6 and 7 based on thio- and selenophosphates is described.

A new strategy for the stereoselective synthesis of olefins

Abstract Highly stereoselective conversion of ketones into (Z)-olefins, via intermediate S-(β-oxoalkyl)thiophosphates and their seleno analogues is described. Conversion of ketones into corresponding olefins via intermediate thiophosphates and their seleno analogues is reported.

The Diels-Alder Reactions of (Z)-1,2-Diheterosubstituted-1,3-Dienes. Sulfur as a Regiochemical Control

Abstract Thermal and Lewis acid catalysed cycloadditions of dienes 1 to dienophiles proceed with complete regio-and stereo-selectivity and provide a route to the cyclic enones.

Synthesis of (z)-1,2-diheterosubstituted-1,3-dienes. novel annelating agents

Abstract Readily available thiophosphates containing an α,β-unsaturated moiety have been efficiently converted into the novel (Z)-1,2-diheterosubstituted-1,3-dienes by treatment with sodium hydride followed by the corresponding electrophile

A general convenient synthesis of conjugated dieneynes

Abstract A convenient synthesis of dieneynes 1 is described. Our strategy involves reaction of readily available thiophosphates with sodium acetylides, in which new single and double carbon–carbon bonds are formed.

Thiophosphates and Selenophosphates in Organic Synthesis. A New Approach to Exocyclic Olefins and Bicyclic Enones

Abstract: Efficient synthesis of α-methylene-cycloalkanones, α-methylene-lactones and α-alkylidene-lactones as well as bicyclic enones were developed using thiophosphates 3, 9, 15 and selenophosphates 4 as key intermediates.

Ketothiolo- and Ketoselenolophosphates as Efficient Reagents in Organic Synthesis

Abstract Novel general routes to thiolophosphates 1 and selenophosphates 2 and their application to regio- and stereoselective synthesis of olefins, functionalized olefins and heterofunctionalized dienes-1, 3 is described.

A NEW SYNTHESIS OF TRI- AND TETRASUBSTITUTED OLEFINS BASED ON THIO- AND SELENOPHOSPHATES

Stereoselective synthesis of tri- and tetrasubstituted functionalized olefins and new phosphates bearing functionalized cyclic substituent has been developed using thiophosphates and selenophosphates as key intermediates.

A New Strategy for the Stereoselective Synthesis of Olefins. Recent Developments

Abstract Stereoselective synthesis of a number of various olefins including functionalized unsaturated compounds based on the S-(β-oxoalkyl) thiophosphates and Se-(β-oxoalkyl) selenophosphates is described.