Pirouz Tahbaz

Stereochemically complementary reductions of indoles

Abstract Indoles containing a 2, 3-fused bridged ring undergo highly stereoselective reduction to cis -fused derivatives with the endo - exo stereochemistry depending on choice of reducing agent.

Diastereoisomerism in 1,3,5-triazine through nitrogen substituents

Abstract The reaction of formaldehyde with ( d,l ) α-methylbenzylamine resulted in a mixture of products of which the desired 1,3,5 triazines 2a and 3a could not be isolated. On the other hand, the reaction of ( d,l ) 2,3 ( trans )-diphenylcyclopropanamine 1b with formaldehyde results in the formation of the diasteromeric nonsymmetrical 1,3,5-triazine 2b and the symmetrical 1,3,5-triazine 3b . These triazines were isolated and their structures were determined by NMR. The stereochemical outcome is discussed.