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Dive into the research topics where Pooja Patnaik Kuppili is active.

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Featured researches published by Pooja Patnaik Kuppili.


Indian Journal of Psychological Medicine | 2017

Cognitive behavior therapy for medically unexplained symptoms: A systematic review and meta-analysis of published controlled trials

Vikas Menon; Tess Maria Rajan; Pooja Patnaik Kuppili; Siddharth Sarkar

Medically unexplained symptoms (MUS) commonly present across the board in medical specialties and are often challenging to treat. Our objective was to assess the efficacy for cognitive-behavior therapy (CBT) in MUS. Electronic search of databases was carried out for published controlled trials in English language peer-reviewed journals from inception till August 2016. Effect sizes for the trials were computed using standardized mean difference, and I2 test was used to assess sample heterogeneity. Pooled mean effect sizes were derived using a random-effects model. Critical appraisal of studies was done using the Cochrane risk of bias assessment tool. A total of 11 trials involving 1235 subjects were included in the study. Ten trials used standard CBT techniques while one studied the efficacy of mindfulness-based CBT technique. The control arms were treatment as usual in five trials, augmented care in four and waitlisted controls in two trials. The pooled mean effect size for CBT was 0.388 (range 0.055–0.806, 95% confidence intervals 0.316–0.461). The I2 value was 0 using a random effects model indicating low heterogeneity among studies. Risk of bias was noted in many included studies. Egger plot intercept indicated potential publication bias. CBT was superior to the waiting list, treatment as usual or enhanced usual care with moderate effect sizes in the treatment of MUS. These findings are impacted by the limited number of studies in this area and questionable methodological rigor of included studies.


Asian Journal of Psychiatry | 2017

DRESS syndrome: Addressing the drug hypersensitivity syndrome on combination of Sodium Valproate and Olanzapine

Venkatalakshmi Penchilaiya; Pooja Patnaik Kuppili; K. Preeti; Balaji Bharadwaj

A case of an adolescent with symptoms of Mania, who developed Drug Reaction with Eosinophilia and Systemic Symptom (DRESS) syndrome on exposure to combination of oral Olanzapine and Sodium Valproate is presented. We have attempted to highlight the atypical presentation of DRESS syndrome in this patient as well as management difficulties in patient who develops DRESS syndrome with the conventional psychotropic medication. Hence, it is necessary for mental health professionals to be vigilant about this life threatening drug reaction associated with high morbidity and mortality, thus ensuring prompt diagnosis and management.


Indian Journal of Psychological Medicine | 2018

Cognitive functions among recently detoxified patients with alcohol dependence and their association with motivational state to quit

Athira Viswam; Padmavathi Nagarajan; Pooja Patnaik Kuppili; Balaji Bharadwaj

Context: Cognitive impairments are common among patients with alcohol dependence. It may involve frontal executive dysfunction, global cognitive impairments, or both. Motivation to quit alcohol involves recognition of alcohol use as a problem. This ability may be construed as a cognitive symptom. Aims: The aim is to study the frequency of cognitive dysfunction among patients with alcohol dependence and to study the association between cognitive dysfunction and the motivation to quit alcohol. Materials and Methods: Fifty-six adult males with alcohol dependence (International Classification of Diseases-10) who had completed a course of detoxification and who did not have active withdrawal symptoms or acute medical illnesses were recruited for this study. Their cognitive functions were tested using the Montreal Cognitive Assessment (MoCA) and Frontal Assessment Battery (FAB). Their motivation levels were assessed using the Stages of Change Readiness and Treatment Eagerness Scale. Clinical details were collected using a semi-structured pro forma. Results: Global cognitive impairment (MoCA < 26) was seen in 81% and frontal executive dysfunction (FAB < 12) in 16% of patients. Higher MoCA and FAB scores correlated with better education, while lower FAB scores correlated with higher age. The 14 patients (25%) with good motivation did not differ in age, education, years of dependence, or MoCA or FAB scores from poorly motivated patients. FAB scores, but not MoCA, were associated with poor motivation. All nine patients with FAB < 12 were poorly motivated to quit alcohol; likelihood score = 5.731, P = 0.017. Conclusions: Four-fifths of patients with alcohol dependence had global cognitive impairments after the detoxification period. One-sixth had frontal executive dysfunction. Cognitive functions were not significantly correlated with the duration of dependence. Presence of frontal executive dysfunction was associated with almost six times likelihood that the patient will be poorly motivated to quit alcohol.


Asian Journal of Psychiatry | 2018

Implications of comorbid ADHD in ASD interventions and outcome: Results from a naturalistic follow up study from south India

Harshini Manohar; Pooja Patnaik Kuppili; Preeti Kandasamy; Venkatesh Chandrasekaran; Ravi Philip Rajkumar

BACKGROUND Autism Spectrum Disorder (ASD) is a neurodevelopmental disorder commonly associated with Attention Deficit Hyperactivity Disorder (ADHD), the prevalence ranging from 14-70%. The current study attempted to assess the impact of comorbid ADHD in children with ASD, in terms of challenges in diagnosis, treatment, intervention outcomes and parental stress and coping through a naturalistic design. METHODS Fifty children aged 2-6 years with ASD were recruited, assessed and followed up for six months. Twenty children were found to have comorbid ADHD. Severity of ASD and ADHD was assessed by Childhood Autism rating scale and Connors abbreviated rating scale respectively. Parental stress and coping was assessed by Family Interview for stress and coping. RESULTS The diagnosis of ASD was apparently obscured by ADHD symptoms in about 22% of cases, as only diagnosis of ADHD was made at the time of referral to our centre. ADHD was the most common comorbidity followed by intellectual disability and seizure disorder. About 66% of children received combination of pharmacological and behavioral interventions. Clonidine was the most common medication to be used and was well tolerated. The improvement in ADHD symptomatology showed positive correlation with improvement with ASD-specific interventions as reflected by change in severity scores. Severity of ADHD significantly also predicted parental stress and coping, and thereby engagement in ASD-specific interventions. CONCLUSION The current study highlights the need for screening and early diagnosis of comorbid ADHD in children with ASD and vice versa considering the management challenges. In case of multiple comorbid neurodevelopmental disorders, early interventions for one disorder can improve the outcome of the other.


Indian Journal of Psychological Medicine | 2017

Ethics in psychiatric research: Issues and recommendations

Shobhit Jain; Pooja Patnaik Kuppili; Raman Deep Pattanayak; Rajesh Sagar

Psychiatric research has increased remarkably over recent decades to help in understanding the current trends and better therapeutic options for illness. On the other hand, there is also a trend toward higher rates of retraction of published papers in the recent years. Ethics is required to maintain and increase the overall quality and morality of research. Psychiatric research faces several unique ethical challenges. Ethical guidelines are very important tool of research which safeguards participants; however, there is a dearth of such guidelines in India. The present paper aims to review available ethical issues and guidelines pertaining to psychiatric research. A search was conducted on Pubmed using search terms (e.g., “ethics,” “psychiatry,” “research”). Relevant studies were selected for the review after manual screening of title/abstract. Additional sources were referred to using cross references and Google Scholar. Psychiatric research has several important ethical issues which are different from other medical disciplines. These issues are related to informed consent, confidentiality, conflict of interest, therapeutic misconception, placebo related, vulnerability, exploitation, operational challenges, among others. The current paper has made several recommendations to deal with ethical challenges commonly faced in psychiatric research. The ethical guidelines are utmost needed for Indian psychiatric research. Specific guidelines are lacking pertaining to psychiatric research. The issues and recommendations merit a further discussion and consideration.


Asian Journal of Psychiatry | 2017

The forgotten entity of cycloid psychosis

Nivedhitha Selvakumar; Pooja Patnaik Kuppili; Balaji Bharadwaj; Preeti Kandasamy

A classic case of Cycloid Psychosis descriptive of “Anxiety Elation” subtype as described by Leonhard with polymorphic presentation of anxiety, elation, perplexity, delusions and hallucinations is presented. We have attempted to highlight the nosological limitations as well as the treatment implications considering the lack of guidelines for management in such cases. We have further discussed the need for validating the entity of Cycloid Psychosis highlighting the differences shared with Schizophrenia and Bipolar Disorder. This case illustrates the need for reporting on Cycloid Psychosis especially from Indian setting where it is found to be common yet under reported.


Asian Journal of Psychiatry | 2017

Thyroid and Cortisol hormones in Attention Deficit Hyperactivity Disorder: A case-control study

Pooja Patnaik Kuppili; Raman Deep Pattanayak; Rajesh Sagar; Manju Mehta; Subbiah Vivekanandhan


Personality and Mental Health | 2018

Personality traits such as neuroticism and disability predict psychological distress in medically unexplained symptoms: A three‐year experience from a single centre

Vikas Menon; Balasubramanian Shanmuganathan; Jaiganesh Selvapandian Thamizh; Anand Babu Arun; Pooja Patnaik Kuppili; Siddharth Sarkar


Asian Journal of Psychiatry | 2018

Olanzapine associated palpebral edema: An uncommon adverse effect of a commonly prescribed drug

Pooja Patnaik Kuppili; Naresh Nebhinani; Shreyance Jain; Kartik Singhai


Asian Journal of Psychiatry | 2018

Being 80% female and 20% male: Delusional pseudotransexualism in a case of Schizophrenia

Pooja Patnaik Kuppili; Sathya Prakash; Koushik Sinha Deb; Rakesh Kumar Chadda

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Balaji Bharadwaj

Jawaharlal Institute of Postgraduate Medical Education and Research

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Vikas Menon

Jawaharlal Institute of Postgraduate Medical Education and Research

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Harshini Manohar

Jawaharlal Institute of Postgraduate Medical Education and Research

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Raman Deep Pattanayak

All India Institute of Medical Sciences

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Preeti Kandasamy

Jawaharlal Institute of Postgraduate Medical Education and Research

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Rajesh Sagar

All India Institute of Medical Sciences

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Karthick Navin

Jawaharlal Institute of Postgraduate Medical Education and Research

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Siddharth Sarkar

All India Institute of Medical Sciences

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Sudhir K. Khandelwal

All India Institute of Medical Sciences

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Anand Babu Arun

Jawaharlal Institute of Postgraduate Medical Education and Research

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