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Dive into the research topics where Pradip K. Sarkar is active.

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Featured researches published by Pradip K. Sarkar.


Journal of Cardiovascular Medicine | 2011

Conduits for coronary artery bypass surgery: the quest for second best.

Sean Oz Bello; Edward Wk Peng; Pradip K. Sarkar

Coronary artery bypass grafting is one of the most outstanding surgical achievements of the 20th century. Over its 50-year history patient outcomes have become excellent owing to technical refinements, myocardial protection, the use of antiplatelet and anticholesterol drugs, and the continued search for better conduits. The performance of conduits used for bypass remains the most important prognostic factor, with the left internal mammary artery being the conduit of choice due to its excellent patency rates. There is, however, uncertainty with regards which conduit is second best. The recent resurgence of the radial artery has led to an increase in its use as surgeons lean towards total arterial revascularization but there is emerging evidence that the performance of the long saphenous vein graft is improving. Furthermore, bilateral internal mammary artery grafting is preferred in some centres as an alternative approach to total arterial revascularization, with multiple reports of superior long-term event-free outcome with its use. This extensive review of current literature reveals an absence of clear consensus as to what mix of conduits provides the best long-term outcomes. The quest for second best continues. Arterial conduits appear to be superior when grafted to tight stenosis but veins remain popular with surgeons. More supportive evidence from the concluding Arterial Revascularization trial and the Radial Artery Patency and Clinical Outcomes trial should guide future practice.


Canadian Medical Association Journal | 2009

Exacerbation of psoriasis with β-blocker therapy

Salman Waqar; Pradip K. Sarkar

A 54-year-old man with a 20-year history of erythrodermic psoriasis underwent coronary artery bypass graft surgery. The patient had no prior history of β-blocker use. He was given the β-blocker bisoprolol postoperatively to treat atrial fibrillation. Within 72 hours after beginning therapy with


Interactive Cardiovascular and Thoracic Surgery | 2008

Successful angiographic embolisation of bleeding into the chest wall after chest drain insertion

Mohammed W. Khalil; Trevor J. Cleveland; Pradip K. Sarkar; Jagan Rao

Peripheral arterial injuries after blunt or penetrating trauma commonly follow injuries to adjacent soft tissue and bone. The traditional approach to these injuries is by open exploration, with identification and ligation of the bleeding vessel. We describe the case of a type II respiratory failure patient who had an enormous pectoral muscle haematoma following chest drain insertion, in whom the bleeding was only controlled by angiographic embolisation following failure of surgical exploration.


The Japanese Journal of Thoracic and Cardiovascular Surgery | 2009

Spontaneous coronary artery dissection

Kareem Salhiyyah; Haitham Abunasra; Salman Waqar; Nigel M. Wheeldon; Pradip K. Sarkar

Spontaneous coronary artery dissection (SCAD) is a relatively rare but important cause of acute coronary syndrome. The diagnosis is often made at autopsy. Risk factors include the peripartum period, oral contraceptive use, and atherosclerotic disease. SCAD must be considered every time a healthy young patient presents with an onset of acute myocardial ischemic syndrome. A timely diagnosis and intervention are mandatory as SCAD can cause sudden death. We describe two cases of SCAD, both treated successfully with emergency coronary artery bypass grafting using left internal mammary and radial arteries in the first case and the left internal mammary artery only for the second case.


Asian Cardiovascular and Thoracic Annals | 2012

Fracture-dislocation of humeral head with intrathoracic displacement

Kareem Salhiyyah; David Potter; Pradip K. Sarkar

Intrathoracic displacement of fractured head of the humerus is a very rare injury. We describe a case of such injury in a 48-old-year lady who presented after a simple fall. She required chest drainage and a thoracotomy to remove the head of the humerus. She subsequently had shoulder hemiarthroplasty with a good outcome.


Cases Journal | 2009

Bilateral coronary ostial disease following mediastinal irradiation: a case report

Salman Waqar; Rajwinder S. Jutley; Richard Mount; Pradip K. Sarkar

IntroductionOstial coronary artery disease is rare with a reported incidence of 0.07 to 0.25% in all patients undergoing angiography. It has a strong association with previous mediastinal irradiation, which induces specific histological changes distinct from atherosclerotic lesions. The radiation also affects the myocardium and surrounding structures, which can alter the surgical approach.Case presentationWe present a case of a 62-year-old female who developed bilateral ostial coronary artery stenosis 32 years following therapeutic radiotherapy for Hodgkins disease. She underwent successful coronary artery bypass surgery using a combination of arterial and venous conduits. Postoperatively she developed a clinical picture of diastolic impairment not detected pre-operatively. She was managed appropriately and made a successful recovery.ConclusionsThis case highlights the cardiac pathology associated with mediastinal irradiation, which should be suspected during surgical assessment, especially in long-term survivors. It heightens the surgeons awareness so a more thorough evaluation of coronary anatomy, ventricular function and potential conduits is made prior to surgery.


Journal of Surgical Technique and Case Report | 2012

The short saphenous vein: A viable alternative conduit for coronary artery bypass grafts harvested using a novel technical approach

Umran Sarwar; Govind Chetty; Pradip K. Sarkar

A multitude of vascular conduits are available to the Cardiac Surgeon performing Coronary Artery Bypass Graft operations. The Internal Mammary Artery, Radial Artery (RA), and the Long Saphenous Vein (LSV) have proven to be excellent conduits, especially in the current era of statin usage. However, previous stripping or varicosities of the LSV and calcification of the RA, coupled with the need for multiple vessel grafting, requires an alternative candidate. We describe a novel harvesting technique for bilateral simultaneous Short Saphenous Vein harvest and propose this, often forgotten vein, as a viable alternative conduit.


The Japanese Journal of Thoracic and Cardiovascular Surgery | 2009

Simple technique of talc delivery for video-assisted talc pleurodesis

Rajwinder S. Jutley; Salman Waqar; Neil Raha; Paul Fenton; Pradip K. Sarkar

It has been proven that talc is the sclerosant of choice for pleurodesis, especially for malignant effusions. Uniform talc deposition on the visceral pleura is often difficult, resulting in clump deposition with the use of an atomizer or bladder syringe delivery apparatus. We have devised a simple sterile apparatus that allows the operator to retain full control over the talc delivery rate and coat the lung uniformly under direct vision using a pressurized system.


Interactive Cardiovascular and Thoracic Surgery | 2009

The risk of fatal re-expansion pulmonary oedema in poor left ventricular reserve

Manish Chowdhary; Edward W.K. Peng; Pradip K. Sarkar

Re-expansion pulmonary oedema (REPO) is an uncommon complication which may be encountered following drainage of pneumothorax, pleural effusion or haemopneumothorax. Treatment is usually supportive and some patients may require positive pressure ventilation. We provide a novel description of the mechanism of a fatal REPO in a patient with a small and non-compliant left ventricle (LV). We urge for an extreme caution when performing thoracocentesis in patients with poor LV reserve.


Heart Surgery Forum | 2007

Massive bilateral pulmonary emboli complicating coronary artery bypass grafting: a case report.

Brian Nyawo; Raja Farhat Shoaib; Sheppard Mary; Pradip K. Sarkar

We report an unusual case of massive bilateral pulmonary emboli following single coronary artery bypass grafting on cardiopulmonary bypass. The patient was admitted electively, received deep vein thrombosis prophylaxis, and had no clinical evidence of deep vein thrombosis in the perioperative period. On the tenth postoperative day he developed sudden dyspnea and a diagnosis of pulmonary embolus was made with computed tomography. Despite full anticoagulation he continued to deteriorate, and despite attempts at pulmonary embolectomy he died of right-sided heart failure. Post-mortem confirmed the diagnosis, but there was no evidence of thrombi in the pelvic and leg veins.

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Edward W.K. Peng

Royal Hospital for Sick Children

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Salman Waqar

Northern General Hospital

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Dheeraj Giri

Northern General Hospital

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Mohammed Asif

Northern General Hospital

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Neil Raha

Northern General Hospital

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