Pramod Joshi
Vertex Pharmaceuticals
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Publication
Featured researches published by Pramod Joshi.
Bioorganic & Medicinal Chemistry Letters | 2014
Pramod Joshi; Corey Anderson; Hayley Binch; Sabine Hadida; Sanghee Yoo; Danielle Bergeron; Caroline J. Decker; Ernst terHaar; Jonathan M. Moore; Miguel Garcia-Guzman; Andreas P. Termin
Calcitonin gene-related peptide (CGRP) has been implicated in acute migraine pathogenesis. In an effort to identify novel CGRP receptor antagonists for the treatment of migraine, we have discovered thiazolidinone 49, a potent (Ki=30 pM, IC50=1 nM), orally bioavailable, CNS-penetrant CGRP antagonist with good pharmacokinetic properties.
Archive | 2005
Dean Wilson; Andreas P. Termin; Jesus E. Gonzalez; Lev T. D. Fanning; Timothy Neubert; Paul Krenitsky; Pramod Joshi; Dennis James Hurley; Urvi Sheth
Archive | 2007
Pramod Joshi; Paul Krenitsky; Jesus E. Gonzalez; Jian Wang; Dean Wilson; Andreas P. Termin
Archive | 2008
Pramod Joshi; Paul Krenitsky; Andreas P. Termin; Dean Wilson
Archive | 2006
Dean Wilson; Andreas P. Termin; Dewey Fanning; Paul Krenitsky; Pramod Joshi; Urvi Sheth
Archive | 2006
Andreas P. Termin; Dean Wilson; Lev T. D. Fanning; Paul Krenitsky; Pramod Joshi
Archive | 2006
Dean Wilson; Lev T. D. Fanning; Paul Krenitsky; Andreas P. Termin; Pramod Joshi; Urvi Sheth
Archive | 2010
Andreas P. Termin; Dean Wilson; Pramod Joshi
Archive | 2006
Andreas Termin; Dean Wilson; Pramod Joshi
Archive | 2006
Dean Wilson; Andreas P. Termin; Lev T. D. Fanning; Paul Krenitsky; Pramod Joshi
