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Featured researches published by Prasanthi Puvanachandra.


Bulletin of The World Health Organization | 2009

Global childhood unintentional injury surveillance in four cities in developing countries: a pilot study

Adnan A. Hyder; David E. Sugerman; Prasanthi Puvanachandra; Junaid Abdul Razzak; Hesham El-Sayed; Andrés Isaza; Fazlur Rahman; Margaret M. Peden

OBJECTIVE To determine the frequency and nature of childhood injuries and to explore the risk factors for such injuries in low-income countries by using emergency department (ED) surveillance data. METHODS This pilot study represents the initial phase of a multi-country global childhood unintentional injury surveillance (GCUIS) project and was based on a sequential sample of children < 11 years of age of either gender who presented to selected EDs in Bangladesh, Colombia, Egypt and Pakistan over a 3-4 month period, which varied for each site, in 2007. FINDINGS Of 1559 injured children across all sites, 1010 (65%) were male; 941 (60%) were aged >or= 5 years, 32 (2%) were < 1 year old. Injuries were especially frequent (34%) during the morning hours. They occurred in and around the home in 56% of the cases, outside while children played in 63% and during trips in 11%. Of all the injuries observed, 913 (56%) involved falls; 350 (22%), road traffic injuries; 210 (13%), burns; 66 (4%), poisoning; and 20 (1%), near drowning or drowning. Falls occurred most often from stairs or ladders; road traffic injuries most often involved pedestrians; the majority of burns were from hot liquids; poisonings typically involved medicines, and most drowning occurred in the home. The mean injury severity score was highest for near drowning or drowning (11), followed closely by road traffic injuries (10). There were 6 deaths, of which 2 resulted from drowning, 2 from falls and 2 from road traffic injuries. CONCLUSION Hospitals in low-income countries bear a substantial burden of childhood injuries, and systematic surveillance is required to identify the epidemiological distribution of such injuries and understand their risk factors. Methodological standardization for surveillance across countries makes it possible to draw international comparisons and identify common issues.


BMC International Health and Human Rights | 2011

Research translation to inform national health policies: learning from multiple perspectives in Uganda

Freddie Ssengooba; Lynn Atuyambe; Suzanne N Kiwanuka; Prasanthi Puvanachandra; Nancy Glass; Adnan A. Hyder

BackgroundResearch and evidence can have an impact on policy and practice, resulting in positive outcomes. However, research translation is a complex, dynamic and non-linear process. Although universities in Africa play a major role in generating research evidence, their strategic approaches to influence health policies and decision making are weak. This study was conducted with the aim of understanding the process of translating research into policy in order to guide the strategic direction of Makerere University College of Health Sciences (MakCHS) and similar institutions in their quest to influence health outcomes nationally and globally.MethodsA case study approach using 30 in-depth interviews with stakeholders involved in two HIV prevention research project was purposively selected. The study sought to analyze the research-to-policy discourses for the prevention of mother-to-child transmission (PMTCT) and safe male circumcision (SMC). The analysis sought to identify entry points, strengths and challenges for research-to-policy processes by interviewing three major groups of stakeholders in Uganda – researchers (8), policy makers (12) and media practitioners (12).ResultsAmong the factors that facilitated PMTCT policy uptake and continued implementation were: shared platforms for learning and decision making among stakeholders, implementation pilots to assess feasibility of intervention, the emerging of agencies to undertake operations research and the high visibility of policy benefits to child survival. In contrast, SMC policy processes were stalled for over two years after the findings of the Uganda study was made public. Among other factors, policy makers demanded additional research to assess implementation feasibility of SMC within ordinary health system context. High level leaders also publicly contested the SMC evidence and the underlying values and messages – a situation that reduced the coalition of policy champions.ConclusionsThis study shows that effective translation of PMTCT and SMC research results demanded a “360 degree” approach to assembling additional evidence to inform the implementation feasibility for these two HIV prevention interventions. MakCHS and similar institutions should prioritize implementation research to guide the policy processes about the feasibility of implementing new and effective innovations (e.g. PMTCT or SMC) at a large scale in contexts that may be different from the research environments.


Salud Publica De Mexico | 2008

Traumatic brain injury in Latin America and the Caribbean: a call for research

Prasanthi Puvanachandra; Adnan A. Hyder

Traumatic Brain Injury (TBI) is a critical public health problem affecting more than 10 million people worldwide and is set to surpass many diseases as the leading cause of mortality and morbidity by the year 2020. The burden of this often neglected injury disproportionately affects low and middle income countries (LMICs) which face not only a higher preponderance of risk factors for TBI but also have less developed health systems to deal with the associated health outcomes. Thus, both the incidence of TBI and the case-fatality from TBI can be high and devastating. Given that TBI can lead to significant mortality and long term morbidity, not to mention the social and financial implications, the silently growing epidemic of this injury is a pressing public health concern. The lack of data concerning the burden of TBI within LAC should be addressed to develop a detailed epidemiological profile in order to plan comprehensive TBI prevention programs. Prioritizing and coordinating funds for the generation of appropriate evidence and research is critical to meet the need to promote evidence-based policy for TBI in the region. Language: en


Traffic Injury Prevention | 2012

Road Traffic Injuries and Data Systems in Egypt: Addressing the Challenges

Prasanthi Puvanachandra; Connie Hoe; Hesham El-Sayed; R. Saad; Naeema Al-Gasseer; M. Bakr; Adnan A. Hyder

Objective: Road traffic injuries (RTIs) are a major cause of global mortality and morbidity, killing approximately 1.3 million people and injuring 20 to 50 million each year. The significance of this public health threat is most pronounced in low- and middle-income countries where 90 percent of the worlds road traffic–related fatalities take place. Current estimates for Egypt show a road traffic fatality rate of 42 deaths per 100,000 population—one of the highest in the Eastern Mediterranean Region. RTIs are also responsible for 1.8 percent of all deaths and 2.4 percent of all disability-adjusted life years (DALYs) lost in the country. Despite this, studies surrounding this topic are scarce, and reliable data are limited. The overall goal of this article is to define the health impact of RTIs in Egypt and to identify the strengths and weaknesses of each data source for the purpose of improving the current RTI data systems. Methods: A 2-pronged approach was undertaken to assess the burden of RTIs in Egypt. First, a thorough literature review was performed using PubMed, Embase, ISIS Web of Knowledge, and Scopus databases. Articles pertaining to Egypt and road traffic injuries were selected for screening. With assistance from Egyptian colleagues, a comprehensive exploration of data sources pertaining to RTIs in Egypt was undertaken and secondary data from these sources were procured for analysis. Results: The literature review yielded a total of 20 studies, of which 6 were multi-country and 5 were hospital-based studies. None examined risk factors such as speeding, alcohol, or seat belt use. Secondary data sources were acquired from national hospital-based injury surveillance; a community-based health survey; pre-hospital injury surveillance; the Ministry of Transport; the General Authority for Roads, Bridges and Land Transport; death certificates; and the central agency for public motorization and statistics. Risk factor data are also limited from these sources. Conclusion: The results of this article clearly highlight the significant burden that road traffic injuries pose on the health of the Egyptian population. The hospital-based injury surveillance system that has been established in the country and the use of International Classification of Diseases (ICD-10) coding brings the system very closely in line with international guidelines. There is, however, some considerable room for improvement, including the need to extend the coverage of the surveillance system, the inclusion of injury severity scores and disability indicators, and standardization of the sometimes rather disparate sources from various sectors in order to maximally capture the true burden of RTIs.


American Journal of Public Health | 2014

Global childhood unintentional injury study: multisite surveillance data.

Siran He; Jeffrey C. Lunnen; Prasanthi Puvanachandra; Amar-Singh; Nukhba Zia; Adnan A. Hyder

OBJECTIVES We aimed to analyze the epidemiology of childhood unintentional injuries presenting to hospitals in 5 select sites in low- and middle-income countries (LMICs) (Bangladesh, Colombia, Egypt, Malaysia, and Pakistan). METHODS We collected standardized data from children ages 0 to 12 years at participating emergency departments (EDs) in 2007. Statistical analyses were conducted to compare the characteristics of these injuries and to explore the determinants of injury outcomes. RESULTS Among 2686 injured children, falls (50.4%) and road traffic injuries (16.4%) were the most common, affecting boys more often (64.7%). Home injuries were more common among younger children (average 5.41 vs 7.06 years) and girls (38.2% vs 31.7%). Following an ED visit, 24% of injured children were admitted to the hospital, and 6 died. Injury outcomes were associated with risk factors, such as age and sex, to varying extents. CONCLUSIONS Standardized ED surveillance revealed unintentional injuries are a threat to child health. The majority of events took place inside the home, challenging traditional concepts of childrens safety and underscoring the need for intensified context-appropriate injury prevention.


Traffic Injury Prevention | 2012

Burden of road traffic injuries in Turkey.

Prasanthi Puvanachandra; Connie Hoe; Türker Özkan; Timo Lajunen

Objective: Road traffic injuries (RTIs) are one of the leading causes of global deaths, contributing to 1.3 million lives lost each year. Although all regions are affected, low- and middle-income countries share a disproportionate burden. The significance of this public health threat is growing in Turkey, where current estimates show that 2.0 percent of all deaths in the country are due to RTIs. Despite the significance of this growing epidemic, data pertaining to RTIs in Turkey are limited. In order to address the gap in knowledge, this article presents an overview of the epidemiology of RTIs in Turkey through an analysis of available secondary data sets and a comprehensive review of scientifically published studies. Methods: A literature review was performed during December 2010 using PubMed, Embase, and ISIS Web of Knowledge databases and Google search engines. Peer-reviewed literature pertaining to Turkey and RTIs were selected for screening. Secondary data were also procured with assistance from Turkish colleagues through an exploration of data sources pertaining to RTIs in Turkey. Results: The literature review yielded a total of 70 studies with publication years ranging from 1988 to 2010. Secondary data sources were procured from the ministries of Health and Interior as well as the Turkish Statistical Institute. These data sources focus primarily on crashes, injuries, and fatalities (crash rate of 1328.5 per 100,000 population; injury rate of 257.9 per 100,000 population; fatality rate of 5.9 per 100,000). Risk factor data surrounding road safety are limited. Conclusion: The findings reveal the significant burden that RTIs pose on the health of the Turkish population. The introduction of new technologies such as the novel digital recording systems in place to record pre-hospital services and Global Positioning System (GPS) tracking of road traffic crashes by the police have allowed for a more accurate picture of the burden of RTIs in Turkey. There are, however, some considerable gaps and limitations within the data systems. Incorporation of standardized definitions, regular data audits, and timely review of collated data will improve the utility of RTI data and allow it to be used for policy influence.


Injury Prevention | 2008

Child and adolescent injuries: a new agenda for child health

Adnan A. Hyder; Prasanthi Puvanachandra; N. H. Tran

Injuries are a major cause of death and disability worldwide and account for more than five million deaths each year; a disproportionate share of this burden is borne by low- and middle-income countries (LMICs).1 Injuries are also among the 10 leading causes of mortality and morbidity in children aged 1–15 years. It is estimated that more than 875 000 children under 18 years of age die annually as a result of all injuries, over 90% of which are unintentional.1 In addition to the loss in mortality, for every child who dies, several thousand children live with injury-induced disability.2 The resulting need for care and rehabilitation has a substantial impact on the child’s future potential, and places a financial and emotional burden on the family. Globally, 98% of all childhood unintentional injuries occur in LMICs, where they have now reached epidemic proportions. In Bangladesh, for example, injuries …


BMC Research Notes | 2012

Understanding unintentional childhood home injuries: pilot surveillance data from Karachi, Pakistan

Nukhba Zia; Uzma Rahim Khan; Junaid Abdul Razzak; Prasanthi Puvanachandra; Adnan A. Hyder

BackgroundChildhood injuries, an important public health issue, globally affects more than 95% of children living in low-and middle-income countries. The objective of this study is to describe the epidemiology of childhood unintentional injuries in Karachi, Pakistan with a specific focus on those occurring within the home environment.MethodsThis was a secondary analysis of a childhood unintentional injury surveillance database setup in the emergency department of the Aga Khan Hospital, Karachi, Pakistan for 3 months. The data was collected by interviewing caretakers of children under 12 years of age presenting with an unintentional injury to the emergency departments of the four major tertiary care hospitals of Karachi, Pakistan.ResultsThe surveillance included 566 injured children of which 409 (72%) injuries had taken place at/around home. Of 409 children, 66% were males and mostly between 5 and 11 years of age. Injuries commonly occurred during play time (51%). Fall (59%), dog bites (11%) and burns (9%) were the commonest mechanisms of injury. The majority of the children (78%) were directly discharged from the emergency room with predicted short term disability (42%). There were 2 deaths in the emergency department both due to falls.ConclusionChildhood injury surveillance system provides valuable in-depth information on child injuries. The majority of these unintentional childhood injuries occur at home; with falls, dog bites and burns being the most common types of unintentional childhood home injuries. Specific surveillance systems for child injuries can provide new and valuable information for countries like Pakistan.


Journal of Public Health Research | 2012

Measuring the health of populations: explaining composite indicators

Adnan A. Hyder; Prasanthi Puvanachandra; Richard H. Morrow

Indicators that summarise the health status of a population and that provide comparable measures of a population disease burden are increasingly vital tools for health policy decision making. Decisions concerning health systems across the world are greatly affected by changes in disease profiles and population dynamics, and must develop the capacity to respond to such changes effectively within the resources of each nation. Decisions must be based on evidence of the patterns of diseases, their risk factors and the effectiveness of alternative interventions. This paper focuses on the main approaches used for developing summary measures that include mortality and morbidity occurring in a population. It discusses the rationale for composite measures and reviews the origins of each main approach. The paper also examines methodological differences among these approaches making explicit the value choices that each entails, outlines the advantages and limitations of each measure, and shows how they relate to one another.


Journal of Public Health Policy | 2011

Commentary: Prevention of violence against children: A framework for progress in low- and middle-income countries

Aruna Chandran; Prasanthi Puvanachandra; Adnan A. Hyder

Violence against children has been the least reported, studied, and understood area of child injuries. Initial awareness emerged from international conferences and resolutions, followed by national policies and statements. More effective responses around the world will require action. Although previous calls for action have pointed to important activities (gathering of baseline data, passing of legal reforms, and providing services to those who experience violence), the agenda is limited. Data collection needs to be continuous, systematic, and sustainable, and should enable ongoing evaluation of intervention programs. An inter-sectoral approach to violence against children incorporating public health, criminal justice, social services, education, non-governmental organizations, media, and businesses is imperative if the growing burden is to be mitigated. Thus we offer a framework, building on earlier recommendations, to focus on four domains: national surveillance, intervention research, legislation and policy, and partnerships and collaboration.

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Adnan A. Hyder

Johns Hopkins University

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Connie Hoe

Johns Hopkins University

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Margie Peden

World Health Organization

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Türker Özkan

Middle East Technical University

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Timo Lajunen

Norwegian University of Science and Technology

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