Preeti Rekha Boruah

A novel green protocol for ligand free Suzuki–Miyaura cross-coupling reactions in WEB at room temperature

A highly efficient green protocol for palladium acetate-catalysed ligand-free Suzuki–Miyaura cross-coupling reactions in neat ‘water extract of banana (WEB)’ was developed. This method offers a mild, efficient and highly economical alternative to the existing protocols since the reaction proceeds in WEB at room temperature in air at very short reaction times (5–90 min) under ‘ligand/external base/external promoter/organic medium’ free conditions.

Pd(OAc)2 and (DHQD)2PHAL as a simple, efficient and recyclable/reusable catalyst system for Suzuki–Miyaura cross-coupling reactions in H2O at room temperature

Suzuki–Miyaura cross-coupling reaction catalyzed by Pd(OAc)2–(DHQD)2PHAL is a very simple, mild and efficient protocol for the synthesis of biaryls/heterobiaryls in neat H2O at room temperature. The catalyst system is recyclable/reusable and can be employed in several consecutive runs without significant loss in catalytic activity.

‘On-water’ organic synthesis: a green, highly efficient, low cost and reusable catalyst system for biaryl synthesis under aerobic conditions at room temperature

A simple, greener, efficient, low cost and mild protocol has been developed for sucrose assisted palladium-catalyzed Suzuki reactions in water at room temperature under aerobic conditions. The results demonstrate that the sucrose played a crucial role making this protocol highly efficient. The PdCl2/sucrose/K2CO3/H2O system showed superb catalytic activity towards the Suzuki reaction of a wide range of aryl/heteroaryl halides with different substituted phenylboronic acids. This method offers an attractive alternative to the existing protocols since the reaction proceeds in aqueous media at room temperature with operational simplicity, shorter reaction time, cost-effectiveness and provides the products in high yields. The catalytic system is highly recyclable, allowing the reuse of the palladium catalyst in subsequent catalytic runs without significant loss of activity.