Preeti Srivastava

Batch and continuous biosorption of Cu2+ by immobilized biomass of Arthrobacter sp.

The ability of free and polysulphone immobilized biomass of Arthrobacter sp. to remove Cu(2+) ions from aqueous solution was studied in batch and continuous systems. The Langmuir and Freundlich isotherm models were applied to the data. The Langmuir isotherm model was found to fit the sorption data indicating that sorption was monolayer and uptake capacity (Q(o)) was 175.87 and 158.7mg/g for free and immobilized biomass respectively at pH 5.0 and 30 degrees C temperature, which was also confirmed by a high correlation coefficient, a low RMSE and a low Chi-square value. A kinetic study was carried out with pseudo-first-order reaction and pseudo-second-order reaction equations and it was found that the Cu(2+) uptake process followed the pseudo-second-order rate expression. The diffusivity of Cu(2+) on immobilized beads increased (0.402x10(-4) to 0.435x10(-4)cm(2)/s) with increasing concentration from 50 to 150mg/L. The maximum percentage Cu(2+) removal (89.56%) and uptake (32.64mg/g) were found at 3.5mL/min and 20cm bed height. In addition to this the Bed Depth Service Time (BDST) model was in good agreement with the experimental data with a high correlation coefficient (>0.995). Furthermore, sorption and desorption studies were also carried out which showed that polysulphone immobilized biomass could be reused for up to six sorption-desorption cycles.

Studies ono-hydroxyacetophenone-2-furoylhydrazone complexes of some 3d-bivalent metal ions

SummaryComplexes ofo-hydroxyacetophenone-2-furoylhydrazone, H2L, of the types M(H2L)C12 · nH2O [Mn = CoII, n=0; NiII, n=2]; Cu(HL)Cl, M(HL)2 [M = VIVO, CoII, NiII or CuII] and M(L)(H2O)n [M = CoII or NiII, n=2; M = CuII, n=0] have been prepared and characterized by elemental analyses, molar conductance, magnetic susceptibility, visible, e.s.r. and i.r. spectral studies. The different modes of ligand chelation and the stereochemistry around the metal ions are discussed.

Studies on 2-aminobenzophenone-2-thenolhydrazone complexes of some bivalent transition metal ions

SummaryComplexes having the chemical compositions [VO(Habth)2SO4], [M(Habth)2Cl2] [M=CoII, NiII, CuII or ZnII) and [M(abth)2] [M=VIVO, CoII, NiII, CuII or ZnII) and Habth=2-aminobenzophenone-2-thenoylhydrazone] have been prepared and characterized. The complexes are non-electrolytes. Magnetic moments and electronic, photoacoustic, e.s.r. and i.r. spectra of the complexes are used to establish the stereochemistry and mode of bonding of the hydrazone.

2-Acetylfuran-2-furoylhydrazone complexes of some 3d-metal ions

Summary2-Acetylfuran-2-furoylhydrazone (1), [HL] reacts with metal ions to yield the complexes of two types, compounds [VO(HL)SO4] and M(HL)2Cl2 [M = CoII, NiII or CuII] and compounds M(L)2(H2O)2 [M = CoII, NiII or CuII], depending on the pH of the medium. These complexes have been characterized by elemental analyses, molar conductance, magnetic susceptibility, visible, e.s.r. and i.r. spectral studies. Square pyramidal geometry for [VO(HL)SO4] and octahedral geometry for the remaining complexes are proposed.

Studies on 2-Acetylpyridine-2-furoylhydrazone Complexes of Some Bivalent Transition Metal Ionsa

Abstract Metal(II) complexes of the compositions M(HL)Cl2 [M = Mn, Co, Zn, Cd, Hg], Ni(HL)2Cl2·4HS2O, Cu(HL)Cl2·3H2O, M(L)2·nH2O [M = Mn, Co, Ni, Cu, Zn] and the oxovanadium(IV) complex, VO(L)2, [HL = 2-acetylpyridine-2-furoylhydrazone] have been prepared and characterized. Molar conductivities indicate non-electrolytic behaviour of the complexes. Magnetic and spectral data such as infrared, electronic and ESR of the complexes are used to establish the stereochemistry and mode of bonding in these complexes.

Studies on 2,6-diacetylpyridine bis(2-furoylhydrazone) complexes of bivalent 3d-metal ions

SummaryThe chelating behaviour of neutral and deprotonated 2,6-diacetyl-pyridine bis(2-furoylhydrazone), H2dapf, has been investigated in some new complexes of oxovanadium(IV), manganese(II), cobalt(II), nickel(II), copper(II) and zinc(II). The hydrazone reacts with the metal salts to yield complexes of two types; the addition compounds [VO(H2dapf)]SO4, [M(H2dapf)Cl]Cl and the deprotonated complexes [M(dapf)H2O] [M=manganese(II), cobalt(II), nickel(II), copper(II) or zinc(II)] in neutral and alkaline media, respectively. The complexes have been characterized by elemental analyses, molar conductance, magnetic susceptibility, electronic, i.r. and e.s.r. studies and their stereochemistries are discussed.

Synthesis and Characterization of Pyrrole-2-Thiocarbgxamide Complexes with Some Bivalent Metal Ions

Abstract Pyrrole-2-thiocarboxamide, HNC4H3C(S)NH2 (ptca), complexes having 1:2 metal-ligand stoichiometry have been prepared and cnaracterized by elemental analyses, molar conductance, magnetic susceptibility, electronic, esr, ir and nmr (1H and 13C) spectral studies. Tetrahedral stereochemistry around Co(II), Ni(II), Zn(II), Cd(II) anHg(II) and five coordinate geometry around Cu(II) have been proposed on the basis of magnetic and spectral studies.

Studies on Acetylacetonebis-(2-Furoylhydrazone) Complexes of Some 3d-Metal Ions

Abstract A number of new complexes of the compositions VO(H2aafh)SO4, M(H2aafh)Cl2 and M(aafh)(H2O)2 [M = Mn(II), Co(II), Ni(II), Cu(II) or Zn(II); H2aafh = acetylacetonebis-(2-furoylhydrazone)] have been synthesized and characterized. Molar conductance values indicate the 1:1 electrolytic nature of the vanadyl complex, the 1:2 ionic behaviour of the Cu(H2aafh)Cl2 complex and the non-electrolytic nature of the remaining complexes in DMF solution. Magnetic susceptibility and spectral studies such as infrared, electronic and electron spin resonance are used to elucidate the structure of the complexes and the mode of bonding of the ligand.

Studies on 2-acetylthiophene-2-furoylhydrazone complexes of 3d-bivalent metal ions

SummaryMetal(II) complexes of 2-acetylthiophene-2-furoylhydrazone (HL) of the types [VO(HL)SO4], [Cu(HL)2Cl2(H2O)], [M(HL)2Cl2] [M=CoII, NiII, or ZnII] and [ML2(H2O)2] [M=CoII, NiII, CuII or ZnII] have been prepared and characterized on the basis of elemental analyses, molar conductance, magnetic susceptibility, visible, e.s.r. and i.r. spectral studies. The bonding and stereochemistry of the complexes are discussed.

Application of Multiplex PCR for Detection of Duchunne Muscular Dystrophy: A Childhood Neuromuscular Disorder

Duchenne muscular dystrophy (DMD) is an X-linked recessive disorder that affects 1 in 3,600 - 6,000 males and is caused by mutation in the dystrophin gene. This is neuromuscular disorder with progressive muscle weakness, which predominantly affect males. Till date no absolute cure of the disease is available in clinical practice. Early diagnosis and timely management are requisite for DMD and it enhances the quality of life of patients. Various diagnostic approaches are available but due to accuracy, early detection and non-invasive method molecular tools are most remarkable in recent era. Multiplex PCR has emerged as one of the most convenient tools for screening of DMD in terms of its sensitivity, specificity, accuracy, cost effectiveness and time consumption. The current study emphasizes advantages and shortcomings of multiplex PCR with reference to most of the past studies along with its challenges for DMD detection in detail. Mutation detection is evidently crucial for diagnosis, as well as it may also be significant for future therapeutic purposes. Further research is important to elucidate specific mutation pattern in association with management and therapies of proband.