Prem Sagar Juneja
Procter & Gamble
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Publication
Featured researches published by Prem Sagar Juneja.
Exogenous Dermatology | 2003
Raphael Warren; James Robert Schwartz; Linda M. Sanders; Prem Sagar Juneja
Background: Dandruff is believed to be a fungus-mediated disease which responds to the topical delivery of antifungal agents. Although the primary causative factor is fungus related, distal events include an inflammatory cascade that eventually expresses itself as corneocyte flakes. The most common vehicle for dandruff treatment includes surfactants (i.e. shampoos), which as a chemical group have the potential to promote dermatitis. Objective: To evaluate the effect of antidandruff agents and antimicrobials on the potential contact irritancy of surfactants. Methods: Excretion of interleukin 1α by human skin equivalent cultures was measured after topical application of test materials. Results: Zinc pyrithione specifically reduces surfactant-induced expression of interleukin 1α. Neither its sodium salt nor other antimicrobial/antifungal agents had a similar effect. Conclusion: These data suggest that in addition to its known antifungal activity, zinc pyrithione may provide an additional benefit by reducing the potential irritancy of surfactant vehicles.
Archive | 1976
Henry Anthony Gieske; Prem Sagar Juneja
Archive | 1992
Prem Sagar Juneja
Archive | 1991
Young Sik Oh; Prem Sagar Juneja; Daniel Stedman Connor
Archive | 2000
Gerald John Guskey; Dennis Ray Bacon; Prem Sagar Juneja; Curtis Bobby Motley; George P. Rizzi
Archive | 1978
Prem Sagar Juneja
Archive | 1992
Prem Sagar Juneja
Archive | 1989
Everett Junior Inman; Nancy J Roberts; Prem Sagar Juneja
Archive | 1988
Paul Robert Tanner; John Paul Luebbe; Richard Martin Ward; Prem Sagar Juneja; Kim William Zerby
Archive | 1989
Prem Sagar Juneja