Network


Latest external collaboration on country level. Dive into details by clicking on the dots.

Hotspot


Dive into the research topics where Premnath Venugopalan is active.

Publication


Featured researches published by Premnath Venugopalan.


Biomaterials | 2002

Gradient crosslinking of UHMWPE using irradiation in molten state for total joint arthroplasty

Orhun K. Muratoglu; Daniel O. O’Connor; Charles R. Bragdon; John Delaney; Murali Jasty; William H. Harris; Edward W. Merrill; Premnath Venugopalan

Increased crosslink density increases the wear resistance of ultra-high molecular weight polyethylene (UHMWPE) acetabular components used in total hip reconstructions. However, increasing crosslink density can reduce the mechanical properties of UHMWPE. Other researchers have tried to limit the crosslinking to a superficial layer on the articulating surfaces to retain the properties of the virgin polymer. We present here a method of producing a gradient of crosslink density across the acetabular component. Acetabular liners with 26 mm inner diameter were machined from the UHMWPE. The liners were then irradiated at 140 degrees C in the molten state of the polymer using a 2 MeV electron beam with limited penetration of the effects of radiation into polyethylene. The liners were then machined to an inner diameter of 32 mm to remove the radiation induced oxidized surface layer. The limited penetration of the e-beam resulted in a gradient of crosslink density with a crosslink density of 0.15 +/- 0.01 mol/dm3 near the articulating surfaces and 0.12 +/- 0.01 mol/dm3 near the backside. The concentration of the trans-vinylene unsaturations decreased gradually as a function of depth from the articulating surfaces to the backside of the liners. The wear resistance of the melt-irradiated liners was contrasted with those of conventional liners using the Boston hip simulator. The gravimetric wear rate was 27 +/- 5 mg million cycles with the conventional liners, while the melt-irradiated acetabular liners did not show any weight loss.


Archive | 1996

Melt-irradiated ultra high molecular weight polyethylene prosthetic devices

Edward W. Merrill; William H. Harris; Premnath Venugopalan; Murali Jasty; Charles R. Bragdon; Daniel O. O'Connor


Archive | 2004

Radiation and melt treated ultra high molecular weight polyethylene prosthetic devices

Edward W. Merrill; William H. Harris; Murali Jasty; Orhun K. Muratoglu; Charles R. Bragdon; Daniel O. O'Connor; Premnath Venugopalan


Archive | 1999

Radiation and melt treated ultra high molecular weight polyethylene prosthetic device and method

Edward W. Merrill; William H. Harris; Murali Jasty; Orhun K. Muratoglu; Charles R. Bragdon; Daniel O. O'Connor; Premnath Venugopalan


Archive | 2000

Process of making ultra high molecular weight polyethylene prosthetic devices

Edward W. Merrill; William H. Harris; Premnath Venugopalan; Murali Jasty; Charles R. Bragdon; Daniel O. O'Connor


Archive | 1999

Prothese de hanche en polyethylene avec amplitude articulaire accrue

Charles R. Bragdon; William H. Harris; Murali Jasty; Edward W. Merrill; Orhun K. Muratoglu; Daniel O. O'Connor; Premnath Venugopalan


Archive | 1997

BESTRAHLTE UND SCHMELTZBEHANDELTE ULTRAHOCH MOLEKULARE POLYETHYLEN PROTHESEN

R. Charles Bragdon; H. William Harris; Murali Jasty; W. Edward Merrill; Orhun K. Muratoglu; O. Daniel O'connor; Premnath Venugopalan


Archive | 1997

Dispositifs de prothese a base de polyethylene a poids moleculaire tres eleve, traites par fusion et rayonnement

Edward W. Merrill; William H. Harris; Murali Jasty; Orhun K. Muratoglu; Charles R. Bragdon; Daniel O. O'Connor; Premnath Venugopalan


Archive | 1997

Bestrahlte und schmeltzbehandelte ultrahoch molekulare polyethylen prothesen Irradiated and schmeltzbehandelte ultrahigh molecular weight polyethylene prostheses

W Merrill; H Harris; Murali Jasty; Orhun K. Muratoglu; R Bragdon; O O'connor; Premnath Venugopalan


Archive | 1997

Bestrahlte und schmeltzbehandelte ultrahoch molekulare polyethylen prothesen Irradiated ultrahigh molecular weight polyethylene and schmeltzbehandelte prostheses

R. Charles Bragdon; H. William Harris; Murali Jasty; W. Edward Merrill; Orhun K. Muratoglu; O. Daniel O'connor; Premnath Venugopalan

Collaboration


Dive into the Premnath Venugopalan's collaboration.

Top Co-Authors

Avatar
Top Co-Authors

Avatar
Top Co-Authors

Avatar

Charles R. Bragdon

Massachusetts Institute of Technology

View shared research outputs
Top Co-Authors

Avatar

Edward W. Merrill

Massachusetts Institute of Technology

View shared research outputs
Top Co-Authors

Avatar

William H. Harris

Massachusetts Institute of Technology

View shared research outputs
Top Co-Authors

Avatar
Top Co-Authors

Avatar
Top Co-Authors

Avatar
Researchain Logo
Decentralizing Knowledge