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Dive into the research topics where Pu-Cha Yan is active.

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Featured researches published by Pu-Cha Yan.


Journal of the American Chemical Society | 2009

Iridium-Catalyzed Asymmetric Hydrogenation of Cyclic Enamines

Guo-Hua Hou; Jian-Hua Xie; Pu-Cha Yan; Qi-Lin Zhou

The first highly enantioselective iridium-catalyzed hydrogenation of cyclic enamines has been developed. This new reaction provided an efficient method for the synthesis of optically active cyclic tertiary amines including natural product crispine A.


ACS Catalysis | 2012

Asymmetric Hydrogenation of Cyclic Imines Catalyzed by Chiral Spiro Iridium Phosphoramidite Complexes for Enantioselective Synthesis of Tetrahydroisoquinolines

Jian-Hua Xie; Pu-Cha Yan; Qian-Qian Zhang; Ke-Xing Yuan; Qi-Lin Zhou


Advanced Synthesis & Catalysis | 2009

Enantioselective Synthesis of Chiral Tetrahydroisoquinolines by Iridium-Catalyzed Asymmetric Hydrogenation of Enamines

Pu-Cha Yan; Jian-Hua Xie; Guo-Hua Hou; Li-Xin Wang; Qi-Lin Zhou


Organic Process Research & Development | 2013

Industrial Scale-Up of Enantioselective Hydrogenation for the Asymmetric Synthesis of Rivastigmine

Pu-Cha Yan; Guo-Liang Zhu; Jian-Hua Xie; Xiang-Dong Zhang; Qi-Lin Zhou; Yuan-Qiang Li; Wen-He Shen; Daqing Che


Chemical Communications | 2014

Direct asymmetric hydrogenation of α-keto acids by using the highly efficient chiral spiro iridium catalysts

Pu-Cha Yan; Jian-Hua Xie; Xiang-Dong Zhang; Kang Chen; Yuan-Qiang Li; Qi-Lin Zhou; Daqing Che


Chinese Journal of Chemistry | 2010

Asymmetric Hydrogenation of Unfunctionalized Enamines Catalyzed by Iridium Complexes of Chiral Spiro N,N-Diarylphosphoramidites †

Pu-Cha Yan; Jian-Hua Xie; Qi-Lin Zhou


Tetrahedron | 2006

A general synthetic route to chiral dihydroxy-9,9'-spirobifluorenes

Xu Cheng; Shou-Fei Zhu; Xiang-Chen Qiao; Pu-Cha Yan; Qi-Lin Zhou


Tetrahedron Letters | 2013

First asymmetric synthesis of Silodosin through catalytic hydrogenation by using Ir-SIPHOX catalysts

Pu-Cha Yan; Xianyi Zhang; Xiao-Wei Hu; Bin Zhang; Xiang-Dong Zhang; Michael Zhao; Daqing Che; Yuan-Qiang Li; Qi-Lin Zhou


Organic Process Research & Development | 2016

Ir/SpiroPAP Catalyzed Asymmetric Hydrogenation of a Key Intermediate of Montelukast: Process Development and Potential Impurities Study

Guo-Liang Zhu; Xiang-Dong Zhang; Li-Jun Yang; Jian-Hua Xie; Daqing Che; Qi-Lin Zhou; Pu-Cha Yan; Yuan-Qiang Li


Tetrahedron Letters | 2013

Corrigendum to ‘First asymmetric synthesis of Silodosin through catalytic hydrogenation by using Ir-SIPHOX catalysts’ [Tetrahedron Lett. 54 (2013), 1449–1451]

Pu-Cha Yan; Xianyi Zhang; Xiao-Wei Hu; Bin Zhang; Xiang-Dong Zhang; Michael Zhao; Daqing Che; Yuan-Qiang Li; Qi-Lin Zhou

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