Qibo Liu

A facile synthesis of diynes

Abstract Terminal alkynes undergo self-coupling reactions in the presence of palladium bis(triphenyl phosphine) dichloride, copper(I) iodide iodine and diisopropyl amine to give the corresponding diynes in good yields.

A novel stereospecific route to E and Z-2-substituted-1,2-difluoroethenylstannanes

Abstract A series of E and Z-2-substituted-1,2-difluoroethenylstannanes are readily obtained in good yield (69–92%) by the reaction of the corresponding fluorinated alkenyl silanes with tributylstannyl chloride and potassium fluoride in DMF under mild conditions.

Stereospecific synthesis of (E)-α,β-difluorostyrenes

Abstract Isomerically pure ( Z )-HFCCFZnI undergoes Pd(PPh 3 ) 4 /CuBr co-catalyzed cross-coupling reactions with aryl iodides in DMAC to give the title compounds in good yields, under mild conditions. In the absence of CuBr, the reaction is sluggish, requires more vigorous reaction conditions, and gives lower yields.