Qingde Yang

Multi-channel electrochemical detection system based on LabVIEW

In this work the design, construction, control and applications of a computerized portable multichannel detection system suitable for electrochemical measurements was developed. The detection system is based on integrated eight homemade miniature potentiostat powered by two 9V batteries. The electrochemical control programme, developed in LabVIEW 6.0, generated the modulation signal, scanned the potential of the working electrode, acquired the current and displayed the results in the form of a voltammogram. The small dimensions, battery operation and inexpensive electronic components make this electrochemical detection system ideal for in situ or field measurements. The utility of the detection system was assessed for the simultaneous determination of four biosensors response to potassium ferricyanide by amperometric and cyclic voltammetry method.

Study of Noninvasive Sampling of Subcutaneous Glucose by Reverse Iontophoresis

As the symmetry of the iontophoresis technique, the reverse iontophoresis technique of extracting and analyzing glucose from the subcutaneous space to the skin surface was described in this paper, as a preliminary step towards the development of noninvasive extracting and analyzing glucose concentrations of human body. Reverse iontophoretic experiments on glucose in sodium chloride solution were performed. The extracted current density was constant 0.5 mA/cm2 and glucose concentration under naked mouse skin was changed in a range of 0 ~ 18 mM. A sensitive amperometric biosensor was designed and prepared for the measurement of the glucose extracted from the subcutaneous space. Our results indicate that reverse iontophoretic extraction has a good correlation with the subcutaneous glucose concentration (r=0.98, n=7). Further research also demonstrates that by addition of EDTA into the cathodal electrolyte could augment the glucose transportation across the naked mouse skin by reverse iontophoresis.