R Buselli
University of Pisa
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Publication
Featured researches published by R Buselli.
Cancer Research | 2005
Alfonso Cristaudo; Rudy Foddis; Agnese Vivaldi; R Buselli; V. Gattini; Giovanni Guglielmi; Francesca Cosentino; Franco Ottenga; Eugenio Ciancia; Roberta Libener; Rosangela Filiberti; Monica Neri; PierGiacoino Betta; Mauro Tognon; Luciano Mutti; Riccardo Puntoni
We conducted a case-control study on asbestos exposure and presence of SV40 in tumor samples of malignant mesotheliomas (MMs) and bladder urotheliomas (BUs). PCR analysis revealed the presence of SV40 DNA (SV40+) in eight (42.1%) MMs and 6 (33.3%) BUs. The odds ratio for MM Asb- and SV40+ was 0.4 [95% confidence interval (95% CI), 0.03-4.0], for Asb+ and SV40- was 3.6 (95% CI, 0.6-21.0), and for Asb+ and SV40+ was 12.6 (95% CI, 1.2-133.9). Our results suggest that SV40 increases the risk of MM among individuals exposed to asbestos.
Thyroid | 2008
Ferruccio Santini; Alberto Mantovani; Alfonso Cristaudo; Teresa Rago; Alessandro Marsili; R Buselli; A Mignani; Giovanni Ceccarini; Rosalinda Bastillo; Donatella Taddei; Ilaria Ricco; Paolo Vitti; Aldo Pinchera
BACKGROUND Many natural substances and drugs have long been known to cause goiter or thyroid dysfunction. More recently, several environmental pollutants, such as pesticides and industrial compounds, have been investigated for their thyroid-disrupting activity and related adverse effects on human health. The aim of this study was to evaluate the effects of styrene on the thyroid axis in occupationally exposed workers. METHODS Thirty-eight exposed (E) and 123 nonexposed (NE) male workers (controls) were assessed. Serum concentrations of thyrotropin (TSH; basal and after thyrotropin-releasing hormone [TRH] administration.), free thyroxine (FT(4)), free triiodothyronine (FT(3)), anti-thyroglobulin, thyroid peroxidase antibody, and calcitonin were measured. Thyroid ultrasound examination was also performed. In E workers, urinary creatinine, mandelic acid (MA), and phenylglyoxylic acid (PGA) were also measured. RESULTS No significant differences between E and NE workers were demonstrated, as far as thyroid volume, nodularity, serum thyroid antibodies, and calcitonin were analyzed. However, in the E group a positive correlation between duration of exposure and thyroid volume was detected. After exclusion of subjects with nodular or autoimmune thyroid diseases, serum concentrations of FT(4), FT(3), and TSH did not differ between the two groups. In E workers there was a positive correlation between the urinary concentrations of styrene metabolites (MA plus PGA) and FT(4) or FT(4)/FT(3) ratio (p < 0.05; r = 0.45 and p < 0.005; r = 0.61, respectively), while no correlation was observed between urinary concentrations of MA plus PGA and serum TSH (either basal and stimulated). CONCLUSIONS Chronic exposure to styrene is not associated with an increase in nodular or autoimmune thyroid diseases. However, styrene could interfere with peripheral metabolism of thyroid hormones by inhibiting T(4) to T(3) conversion. Whether this is a direct effect on iodothyronine deiodinases or a consequence of a general distress, such as in nonthyroidal illnesses, remains to be established. Further studies in a larger population of exposed workers are needed to confirm these preliminary observations.
Medicina Del Lavoro | 2006
R Buselli; C Gonnelli; M Moscatelli; Cioni; Giovanni Guglielmi; Gattini; Rudy Foddis; A Mignani; Franco Ottenga; Alfonso Cristaudo
Giornale italiano di medicina del lavoro ed ergonomia | 2007
Rudy Foddis; Agnese Vivaldi; Rosangela Filiberti; Riccardo Puntoni; L Mutti; Nicolino Ambrosino; Antonio Chella; Giovanni Guglielmi; Gattini; R Buselli; Salvio Perretta; Alfonso Cristaudo
Medicina Del Lavoro | 2016
R Buselli; Antonello Veltri; Sigrid Baldanzi; Silvia Bozzi; Riccardo Marino; Martina Chiumiento; Liliana Dell'Osso; Alfonso Cristaudo
Giornale italiano di medicina del lavoro ed ergonomia | 2012
Cosentino F; R Buselli; Baldanzi S; Caldi F; Bozzi S; Giorgi R; Bonotti A; Alfonso Cristaudo
Giornale italiano di medicina del lavoro ed ergonomia | 2007
Silvia Simonini; Rudy Foddis; Rosangela Filiberti; Riccardo Puntoni; L Mutti; Nicolino Ambrosino; Antonio Chella; Giovanni Guglielmi; R Buselli; Marta Iuzzolini; A Mignani; Franco Ottenga; Alfonso Cristaudo
6th Conference Work Organization & Psychosocial Factors | 2017
R Buselli; Sigrid Baldanzi; Silvia Bozzi; Antonello Veltri; Alfonso Cristaudo
Medicina Del Lavoro | 2015
R Buselli; Silvia Bozzi; Martina Chiumiento; Riccardo Marino; Lucia Doretti; Antonello Veltri; Sigrid Baldanzi; Fabrizio Caldi; Alfonso Cristaudo
Journal of Sleep Research | 2012
Michelangelo Maestri; Francesca Cosentino; E Di Coscio; E Iacopini; Luca Carnicelli; R Buselli; Sergio Garbarino; Alfonso Cristaudo; Enrica Bonanni