R. Carrie

Reduction d'azides en amines primaires par une methode generale utilisant la reaction de staudinger

Abstract A general chemoselective method for the reduction of azides into primary amines is described.

Synthese de cyclopropanes electrophiles chiraux par l'intermediaire de complexes butadiene-fer tricarbonyle optiquement actifs.

Resume Chiral electrophilic cyclopropanes are prepared, in high enantiomeric excess (e.e > 90 %) starting from the optically active complexes 3a and 3b . A simple and efficient method. for the resolution of the key intermediate complex 1 is described.

Syntheses asymetriques a l'aide d'oxazolidines chirales derivees de l'ephedrine. Preparation de formyl cyclopropanes chiraux.

Resume Chiral oxazolidines 2 are very simple and highly efficient inducing groups for asymmetric synthesis during cycloaddition reactions. Chiral Formyl cyclopropanes are easily obtained in high enantiomeric excess (⩾ 90 %).

Etude de la chimioselectivite de la reaction des dichloroboranes avec les azides fonctionnels : une synthese efficace d'amines secondaires fonctionnalisees.

Abstract The reaction of cyclohexyldichloroborane, used as a model, with a wide variety of functionalized azides has been studied. It has been shown to be an efficient synthesis of secondary amines in terms of chemioselectivity, yields and wide applicability.

Unhindered phosphaalkenes and phosphaalkynes in stable condition from a vacuum multistep sequence.

Abstract Unhindered low coordinated phosphines 5 - 6 are obtained in stable condition starting from dichlorophosphines 3 and 4 by a Flash Vacuum Thermolysis/Gas Solid Reaction sequence (FVT/GSR) and fully characterized by 1H, 13C and 31P NMR spectroscopy.

The use of ω-iodoazides as primary protected electrophilic reagents. Alkylation of some carbanions derived from active methylene compounds and N,N-dimethylhydrazones

Summary Some carbanions derived from active methylene compounds and N,N-dimethyl-hydrazoneswere alkylated in good yields with the ω-iodoazides 3,4 and 13 used as primary amino protected electrophilic reagents.

A new efficient access to cyclic imines

Cyclic imines can be conveniently prepared from ω-azidoketones by an intramolecular ‘aza-Wittig’ reaction.

A convenient highly stereoselective synthesis of cyclopropylboronates

Abstract Carbenes generated from diazocompounds in the presence of palladium acetate add to vinylboronates, thus achieving an efficient highly stereoselective synthesis of functionalized cyclopropylboronates.

Stereoselective synthesis and Diels-Alder reactions of bis-Ether 1,3 Dienes. A further test for cooperativity during cycloaddition reactions.

A stereoselective synthesis of dienes 1a and 1b, using butadiene-iron tricarbonyl complexes, is described. Higher diastereoselectivity is observed during Diels-Alder reaction of 1a as compared with 1c, affording good evidence for cooperativity in these cycloadditions.

Ligand assisted hydride delivery : An expeditious stereoselective total synthesis of (±) nor-sedamine and its pyrrolidino analog

Abstract The principle of an efficient stereoselective one pot synthesis of γ-aminoalcohols is reported and applied to the total synthesis of (±) nor-sedamine and its pyrrolidino analog.