R. Sinna

Fat Injection to the Breast: Technique, Results, and Indications Based on 880 Procedures Over 10 Years

BACKGROUND Fat injection to the breast is not a new idea, but it has always been controversial. In particular, it has been feared that breast augmentation with autologous fat could lead to the formation of calcifications and cysts that might hinder mammagraphic examinations for detection of possible breast cancer. OBJECTIVE The authors report their experience with fat transplantation in the breast (lipomodeling) covering 880 procedures performed over the past 10 years. They review their technique and results, and describe the various indications for which they have found lipomodeling to be appropriate. METHODS Lipomodeling was generally performed under general anesthesia. Fat was harvested from the abdomen or in some cases from the inner thighs, depending on the patients natural fat deposits. The harvested fat was centrifuged to obtain purified fat, which was transferred to 10-mL syringes for injection directly into the breast. Fat was injected in small quantities under light pressure, utilizing a honeycomb of microtunnels and halting when the recipient tissues were saturated to avoid creation of fatty pools that could lead to fat necrosis. To compensate for fat resorption, 140 mL of fat was injected for a desired final volume of 100 mL. RESULTS Clinical follow-up shows that the morphologic results of lipomodeling with regard to the volume obtained are stable three to four months postoperatively if the patients weight remains constant. The postoperative radiologic appearance is usually that of normal breasts, sometimes showing images of fat necrosis that will not confuse the differential diagnosis of cancer for radiologists experienced in breast imaging. Oncologic follow-up at 10 years postoperatively (for the first patients) showed no increased risk of local recurrence of cancer or development of a new cancer. Results were highly satisfactory for both patients and surgeons. Complications included one case of infection at the harvest site, six cases of infection at the injection site, and one case of intraoperative pneumothorax that was successfully treated in the recovery room with no later consequences. The incidence of fat necrosis was 3%, with most cases occurring early in the surgeons experience. CONCLUSIONS Lipomodeling, because of a low complication rate and positive results, presents a new option for plastic, reconstructive, and aesthetic surgery of the breast. Pre- and postoperative examination by a radiologist specialized in breast imaging is necessary to limit the risk that a cancer may occur coincidentally with lipomodeling.

Breast fat grafting (lipomodelling) after extended latissimus dorsi flap breast reconstruction: a preliminary report of 200 consecutive cases.

BACKGROUND The efficacy of fat grafting has long been a controversial issue. Breast lipomodelling after extended latissimus dorsi flap reconstruction was first attempted at the Plastic and Reconstructive Surgery unit of Leon Berard Cancer Centre in 1999. We present the results of a retrospective report of the first 200 consecutive patients treated at our institution from 1999 to 2003. METHODS We identified specific requirements of the patients, and collected information on the surgical techniques used and the volumes of fat tissue injected. We analysed and compared the results of a total of 244 lipomodelling sessions. RESULTS The graft consisted of 70% fat graft, 13% oily supernatant and 17% serum residues. Approximately 30% was lost during centrifugation. On average, 176 ml of fat were injected in each breast. Very satisfactory results were obtained in 94.5% of the cases, with a majority of patients (80%) being very satisfied with the procedure and only 1.5% complications. CONCLUSION Our results demonstrate the safety and feasibility of breast lipomodelling. It is a new approach to improve reconstructive outcome after extended latissimus flap breast reconstruction.

Vascular basis of the facial artery perforator flap: analysis of 101 perforator territories.

Background: The facial artery perforator flap was developed to perform more accurate reconstruction of perioral and nasal alar defects. This technique allows tailor-made reconstruction and shifting from the traditional two-stage procedure to a one-stage technique. Cadaveric studies have described the number, location, and size of facial artery perforators. Understanding of the facial artery blood supply can be complete, however, only if the cutaneous supply of each perforator is known. Methods: The authors performed 20 dissections of facial arteries on fresh cadavers. All facial artery perforators greater than 0.5 mm were dissected and the diameters measured. All perforators were selectively injected with 1 ml of diluted ink solution. All these results were statistically analyzed. Results: Twenty facial arteries were dissected, with a mean length of 12.06 cm. The average number of perforators greater than 0.5 mm per facial artery was 5.05. The mean diameter of the perforators was 0.96 mm. A total of 101 perforators were selectively injected, and the mean size of all injected skin areas was 8.05 cm2. Seven main, reliable types of perforator territory were identified. Conclusions: Facial artery perforators seem to be predominantly between 1 and 2 cm lateral to the level of the oral commissure. Seven main types of perforasomes have been identified and appear to be the basis for local flap design. This study improves our understanding of facial vascularization and will allow the face to give up the era of random flaps to take advantage of more accurate reconstructions from the rest of the body.

Tuberous breast correction by fat grafting.

INTRODUCTION Tuberous breast is a rare malformation that has negative physical and psychological impacts during puberty. A range of surgical techniques has been used to correct breast shape and volume in this context, including a combination of skin plasty and mammary gland remodeling, as well as prostheses and locoregional flaps. The authors have used fat grafting as a complementary technique to correct tuberous breasts since 1998. OBJECTIVES The authors discuss application of their lipomodeling technique for correction of tuberous breast deformity. METHODS The charts of tuberous breast patients treated consecutively over an 11-year period (n = 31) solely with fat grafting (ie, without using an implant) were retrospectively reviewed. Each breast deformation was graded according to the Grolleau classification. The number of sessions and the mean transfer of fat volume by lipomodeling session were recorded. Patient and surgeon satisfaction were evaluated. RESULTS Of the 31 patients in this series, 18 had bilateral formations and 13 had unilateral malformations. The mean patient age was 23 years, and the mean body mass index was 21.9. A single session (mean transfer volume, 158 mL; range, 90-253 mL) was required in 14 (45%) cases. A second session (mean transfer volume, 226 mL; range, 100-316 mL) was necessary in the remaining 55% of cases. Mean follow-up period after the last fat transfer session was 6.5 years (range, 1.5-11 years). Patients were very satisfied in 94% of cases (n = 29) and satisfied in 6% (n = 2). The surgical team rated 94% of cases as being successful or very successful. No complications were observed. One patient developed hypertrophy of the treated breast following weight gain and thus required breast reduction. Imaging performed preoperatively and 1 year postoperatively did not reveal any anomalies other than oil cysts. CONCLUSION Fat grafting is a reliable technique that produces excellent results and high levels of patient satisfaction for the treatment of tuberous breast. The aesthetic outcome is natural, implant free, and long lasting. LEVEL OF EVIDENCE 4.

Perforator flaps: a new option in perineal reconstruction.

Over the past few decades, methodological progress and better anatomical knowledge have reduced the morbidity of reconstructive surgery. Muscle-sparing flaps and perforator flaps provide the surgeon with additional options for reconstruction. Based on a review of the local flaps used for perineal reconstruction, this article describes these new solutions and presents a decision tree (based on whether abdominal incision is required or not). If laparotomy is required, abdominal flaps should be preferred. If surgical excision is performed with the patient in the prone position, then gluteal and pudendal donor sites are recommended.

Reconstruction mammaire par transfert graisseux exclusif : à propos de 15 cas consécutifs

UNLABELLED BACKGROUND OF STUDY: The purpose of this prospective study is to detail the preliminary results, the advantages and drawbacks of a new iterative fat transfer protocol in selected breast reconstructions. MATERIAL AND METHODS Fifteen patients had breast reconstruction following mastectomy for breast cancer by this iterative lipomodeling protocol, between 2002 and 2007. Clinical and technical aspects are described. Indications, advantages, drawbacks, complications and morphological results are discussed. RESULTS Mean age at first stage procedure was 50 years (min: 41, max: 57). Indications were eight delayed breast reconstructions, three salvage reconstructions after flap failure, two restorations following primary chest wall reconstruction, two immediate breast reconstructions. Two to five sequential procedures were necessary to obtain a satisfactory breast volume (mean: three procedures). Mean total transferred fat volume was 600 cm(3) (min: 266 cm(3), max: 926 cm(3)). Multiple procedures were performed: restoration of breast skin envelope by abdominal advancement fasciocutaneous flap, breast contours liposuction, controlateral breast symmetrisation, nipple areola complex reconstruction. Mean follow-up was 28 months. The aesthetics results have been judged as very good in 10 patients, good in four patients and poor in one patient. The satisfaction rate of the patients is high: 10 patients are pleased, four patients are satisfied and one patient is moderately satisfied. CONCLUSION Fat transfer alone can efficiently restore breast volume after mastectomy, granting all advantages related with autologous reconstruction. No donor site morbidity is present; in fact some secondary benefits are observed thanks to the correction of eventual disgraceful lipodystrophies. These secondary benefits strengthen patient compliance improving iterative procedures tolerance. Lack of available adipose tissue and high breast volume are the major morphological limits of the technique. In our experience, fat transfer appears to be a promising technique for breast reconstruction. Long term results still have to be evaluated before it can become a standard.

Percutaneous fasciotomies and fat grafting: indications for breast surgery.

BACKGROUND The management of breast deformities can be very difficult in the presence of breast shape retraction. Percutaneous fasciotomies, which release fibrous strings, can be a very useful tool for shape improvement in the recipient site for a fat graft. OBJECTIVES The authors evaluate the efficacy of fasciotomies in association with fat grafting in breast surgery. METHODS A retrospective chart review was conducted for 1000 patients treated with concurrent fasciotomies and fat grafting between January 2006 and December 2011. The recipient site was prepared with fasciotomies, and fat was harvested from other parts of the body using a low-pressure 10-mL syringe lipoaspiration system. Fat was centrifuged and injected into the breast for reconstruction or chest deformities. The postoperative appearance of the breast scars was scored by both the surgeon and the patient. Each complication was recorded, including instances of hematoma, infection, tissue wounds, scar healing, and fat necrosis. RESULTS In this series of patients, for whom the primary indications for the procedure were sequelae of breast-conserving surgery after cancer, latissimus dorsi flap breast reconstruction, breast implant reconstruction, tuberous breast, Poland syndrome, and funnel chest, we recorded the following complications: 0.8% local infections (8/1000), 0.1% delayed wound healing that required medical care (1/1000), and 3% fat necrosis (31/1000). Fasciotomy scarring was considered minor by the patient in 98.5% of cases and by the surgeon in 99% of cases at 1 year postoperatively. CONCLUSIONS Fat grafting is a safe and reliable technique that improves the aesthetic outcomes of breast surgery. Percutaneous fasciotomies provide excellent aesthetic results and an improvement in breast shape with no scarring. In our experience, both fat grafting and fasciotomies offer a durable result over the long term.

What should define a "perforator flap"?

Summary: In spite of the Gent consensus on perforator flap terminology, widespread confusion still exists regarding the true description of these flaps, making it hard to understand these surgical procedures in comparison with conventional flap techniques. The value of perforator flaps can be better understood by further clarifying certain aspects of previous descriptions. The authors would like to propose enriching the standard Gent nomenclature with optional terms that specify additional aspects of the perforator flap such as including the vessel of origin, the type of vascular dissection, the muscle involved, and the type of perforator vessel. When describing a new flap, these terms will help clarify the anatomical aspects and the surgical approach. Lastly, a better understanding will help in the ongoing debates on this type of surgery and will aid in its dissemination and adoption into reconstructive practice.

Patient Information Before Aesthetic Lipomodeling (Lipoaugmentation): A French Plastic Surgeon's Perspective

Fat grafting to the breasts has long been controversial among aesthetic surgeons. We have developed a new, safe, effective, and reliable lipomodeling method to be used in breast augmentation. This method grew out of our clinical and radiologic experience acquired since 1998 with fat injections to the breast. The aim of the present report is to provide facts and data concerning lipomodeling and to document our procedures for ensuring that clear, consistent, up-to-date information is given to the patients who are undergoing aesthetic lipomodeling. The key element in our preparation is our commitment to avoid missing the diagnosis or altering the presentation of a preexisting or newly arising breast cancer. We must also ensure that the patient understands the need to comply with follow-up recommendations, such as a specific radiologic examination before and one year after the procedure, as well as a biopsy evaluation of any lesion that is considered suspicious during the physical examination. The patient must sign a confirmation that she has received the appropriate information and that she understands the notice provided by the surgeon at her first visit. This notice must deliver clear, complete, objective, evidence-based information, must be written clearly and understandably, and must not contain any unrelated or confusing information.

Double L-shaped free-style perforator flap for perineal and vaginal reconstruction after cylindrical abdominoperineal resection.

The improvement of patient carcinological status by an abdominoperineal resection by extended posterior perineal approach in a prone position requires the plastic surgeon to consider other reconstructive options. We present an original double L-shaped free-style propeller flap used to reconstruct the vagina and the perineum of a 57-year-old patient after the resection of a T4 tumour of the lower rectum.