R. Suresh Kumar

Clinical Evaluation of Haloperidol as an Adjuvant to Thiopentone and Ketamine Anesthesia in Dogs

The clinical assessment of haloperidol as adjuvant to thiopentone and ketamine anesthesia in dogs was studied. Induction of anesthesia with thiopentone was rapid (1.50±0.07 minutes) smooth and without any complications whereas induction with ketamine was a little slower (1.94±0.04 minutes).The mean duration of surgical anesthesia in thiopentone group (I) and ketamine group (II) were 41.0±0.94 and 28.0±4.09 minutes respectively. Complete recovery took place within 120.0 ±3.9 minutes in group I and at 46.0±0.24 minutes after the last incremental dose in group II. The mean rectal temperature were 101.66±0.53OF and 101.96±0.38OF in group I and II respectively and the values remained within the normal range Haloperidol not only potentiated the anesthetic effects of thiopentone but helped to prolong the duration of anesthesia.

Histopathological and ultra structural studies of ovine pulmonary adenocarcinoma (Jaagsiekte)

The Ovine Pulmonary adenocarcinoma (OPA) is also known as Jaagsiekte, is a contagious transmissible lung tumor of sheep caused by Jaagsiekte Sheep Retrovirus (JSRV). In the present study, 3698 lungs collected from slaughtered sheep in and around Tirupati, AP, India and examined morphologically. 396 lungs were showed different pneumonic lesions. Among 396 lung lesions 39 (9.85%) were diagnosed as Pulmonary adenocarcinoma. Grossly, all the lungs congested, increase in size, weight and oedematous. Consistency varied from granular to meaty appearance and many of them revealed nodules ranging from very small to 2.5 cm in diameter and serous exudate on cut surface of lung. Histologically, Papillary projections of epithelium into either alveolar or bronchiolar lumen. Intra alveolar fibrosis was prominent in many cases. Alveolar macrophages were consistently found within alveolar spaces. OPA also associated with different types of pneumonias. Ultrastructurally, proliferation of type II pneumocytes (Type B cells) having microvilli and well developed junctional complexes. Non ciliated bronchiolar epithelial cells (Clara cells) with electron dense cytoplasmic granules without any surrounding membrane and microvilli and no virus particles were traced.

Ovariectomy in forty rats (Rattus norvegicus).

The present paper describes the mid-ventral ovariectomy in 40 rats and its successful surgical management. The operation, performed in the mid ventral incision was technically easier, minimally invasive and easy to locate the ovary embedded in fat, less time consuming and less harmful for the rats.