R. van Helden

Palladium-catalysed carbonylation of unsaturated compounds☆

Abstract The oxiative carbonylation of olefins in the presence of palladium(II)/copper(II) as catalyst yields β substituted and/or α-β unsaturated carboxylic acid derivatives. The palladium-catalyzed carbonylation of allylic compunds affords β-γ unsaturated carboxylic acid derivatives, while tertiary allylamines can be converted into γ-amino acids. The interaction of confugated and cumulated dienes with π-allylic palladium complexes is described as part of palladium-catalysed synthesis of polyunsaturated carboxylic acid derivatives from a diene, an alcohol and carbon monoxide or from a diene, an allylic compound and carbon monoxide. The kinetics and mechanisms of these reaction are discussed.