Rafał Celiński

Identification and characterization of new designer drug 4-fluoro-PV9 and α-PHP in the seized materials

In this study, we present identification and physicochemical characterization of new cathinone derivatives, 4-fluoro-PV9 and already known α-PHP in seized materials. Although the disclosure of α-PHP from an illegal product had been reported and characterized to some extent, the data on α-PHP are also presented together with those of 4-fluoro-PV9. The data of characterization for the two compounds were obtained by high-performance liquid chromatography (HPLC)–mass spectrometry and HPLC–diode array detection, electrospray ionization/ion trap mass spectrometry in MS2 and MS3 modes, gas chromatography–mass spectrometry, thermogravimetric analysis, differential scanning calorimetry, Fourier transform infrared spectroscopy, ultraviolet-visible spectroscopy, and nuclear magnetic resonance spectroscopy. To our knowledge, this is the first report for identification and detailed characterization of 4-fluoro-PV9 circulated on the illegal drug market.

1‐O‐p‐Toluene­sulfonyl‐2,3:4,5‐di‐O‐iso­propyl­idene‐l‐arabitol

In the title compound, C18H26SO7, the absolute configuration was confirmed as S at all three chiral centres. Molecules are linked by three C—H⋯O contacts.

Structure elucidation of 2-amino-5-phenyl-2-oxazolin-4-one (pemoline) and X-ray structure of its hydrolysis product 5-phenyl-oxazolidine-2,4- dione

In this study we compare spectroscopic properties of pemoline (2-amino-5-phenyl-2-oxazolin- 4-one) and its acid hydrolysis product 5-phenyl-oxazolidine-2,4-dione. Crystallization of pemoline from aqueous acetic acid gave single crystals of compound 2, the structure of which was determined by X-ray studies. All four crystallographically independent molecules form dimers linked by N-H···O = C hydrogen bonds.