Rainer Mahrwald

Modern Aldol Reactions

Fundamentals and Transition State Models.The Development of Titanium Enolate Based Aldol Reactions.Boron and Silicon Enolates in Crossed Aldol Reaction.Silver, Gold and Palladium Lewis-Acids.Boron and Silicon Lewis Acids for Mukaiyama Aldol Reactions.Copper Lewis Acids.Tin-promoted Aldol Reactions and Their Applications to Total Syntheses of Natural Products.Zirconium Alkoxides as Lewis Acids.Direct Catalytic Asymmetric Aldol Reaction Using Chiral Metal Complexes.Catalytic Enantioselective Aldol Additions with Chiral Lewis Bases.Amine-Catalyzed Aldol Reactions.Enzyme Catalyzed Aldol Additions.Antibody-Catalyzed Aldol Reactions.The Aldol-Tishchenko Reaction.The Aldol Reaction in Natural Product Synthesis: The Epothilone Story.

Enantioselective organocatalyzed reactions I

Enantioselective organocatalyzed reactions I , Enantioselective organocatalyzed reactions I , کتابخانه دیجیتال جندی شاپور اهواز

Modern Organocatalyzed Methods in Carbohydrate Chemistry

For a long time carbohydrates have stood out as a class of compounds very difficult to synthesize due to complexity of configuration and functionality. Delicate chemical operations and separation problems resulted in the so-called “sugarophobia”. But based on the dramatic development of organocatalysis over the last 15 years a large number of complicated carbohydrates is now accessible. Today a big manual of synthetic methods for total synthesis of carbohydrates exists. This pool of synthetic methods provides the tools to create defined and required configurations of hydroxyl groups during the total synthesis of the desired carbohydrates. Due to the nature of carbohydrates different aldol additions are the favoured transformations for the synthetic access to carbohydrates. Especially the extremely fast-growing manual of organo-catalyzed aldol reactions represents a promising tool for direct and biomimetic synthesis to unusual enantiomers of monosaccharides and to deoxy-, branched-, amino-, thioand carbon-substituted carbohydrates.