Rainer Ziermann
Kosan Biosciences
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Publication
Featured researches published by Rainer Ziermann.
Gene | 2000
Bryan Julien; Sanjay Shah; Rainer Ziermann; Robert Goldman; Leonard Katz; Chaitan Khosla
The epothilone biosynthetic gene cluster was isolated from Sorangium cellulosum strain SMP44. The gene cluster contains seven genes and spans approx. 56kb. The genes encoding the PKS, epoA, epoC, epoD, epoE, and epoF, are divided into nine modules. The EpoB protein is a non-ribosomal peptide synthetase (NRPS) that catalyzes formation of the thiazole found in the epothilones. EpoK is a P450 enzyme responsible for the epoxidation of epothilones C and D to epothilones A and B, respectively. EpoK was expressed in Escherichia coli, and the purified protein was shown to convert epothilone D to epothilone B in vitro.
Archive | 2000
Bryan Julien; Leonard Katz; Chaitan Khosla; Li Tang; Rainer Ziermann
BioTechniques | 1999
Rainer Ziermann; Mary Betlach
Archive | 1997
Philip J. Barr; Daniel V. Santi; Gary W. Ashley; Rainer Ziermann
Archive | 2000
Bryan Julien; Leonard Katz; Chaitan Khosla; Li Tang; Rainer Ziermann
Archive | 1998
Rainer Ziermann; Mary Betlach
Archive | 1998
Claes Gustafsson; Mary C. Betlach; Gary W. Ashley; Bryan Julien; Rainer Ziermann
Archive | 2006
Bryan Julien; Leonard Katz; Chaitan Khosla; Li Tang; Rainer Ziermann; コースラ チャイタン; ジュリアン ブライアン; タン リー; ツィアーマン レイナー; カッツ レオナルド
Archive | 1999
Bryan Julien; Leonard Katz; Chaitan Khosla; Li Tang; Rainer Ziermann
Archive | 1997
Gary W. Ashley; Philip J. Barr; Daniel V. Santi; Rainer Ziermann
