Rajata Rajatanavin
Walter Reed Army Institute of Research
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Featured researches published by Rajata Rajatanavin.
Clinical Endocrinology | 2008
La-or Chailurkit; Suwannee Chanprasertyothin; Rajata Rajatanavin; Boonsong Ongphiphadhanakul
Objectiveu2002 To investigate the effect of oral glucose on bone resorption and osteoprotegerin (OPG) in subjects with varying degrees of glucose tolerance.
Clinical Endocrinology | 2010
La-or Chailurkit; Sunee Saetung; Ammarin Thakkinstian; Boonsong Ongphiphadhanakul; Rajata Rajatanavin
Objectiveu2002 To investigate the influence of vitamin D status on parathyroid hormone and bone mass after a 2‐year supplementation of calcium alone.
Journal of Pediatric Endocrinology and Metabolism | 2005
Preamrudee Poomthavorn; Pat Mahachoklertwattana; Boonsong Ongphiphadhanakul; Chawalit Preeyasombat; Rajata Rajatanavin
BACKGROUNDnChronic subclinical hyperthyroidism induced by suppressive doses of L-thyroxine (L-T4) therapy, so-called exogenous subclinical hyperthyroidism, may cause diminished bone mass in postmenopausal women. The effect of subclinical hyperthyroidism during childhood and adolescence on peak bone mass, however, has not been evaluated.nnnOBJECTIVEnTo determine whether exogenous subclinical hyperthyroidism during adolescence, the period of critical bone mass acquisition, would reduce peak bone mass.nnnPATIENTS AND METHODSnEighteen female adolescents and young adults with Hashimotos thyroiditis and euthyroid goiter (aged 22.4 +/- 4.4 years) who had been treated with suppressive doses of L-T4, 127.5 +/- 23.7 microg/day, during adolescence (age at onset of subclinical hyperthyroidism, 14.2 +/- 1.5 years) for 6.3 +/- 3.4 years were enrolled in the study. Twenty-nine healthy female volunteers matched for age, weight, height and body mass index served as the controls. Bone mineral density (BMD) was measured by dual energy X-ray absorptiometry.nnnRESULTSnBMD of the lumbar spine, radius, Wards triangle and total body were comparable in the two groups. In contrast, BMD of the femoral neck, trochanter and shaft of patients was slightly higher than those of controls. There were no correlations between BMD values and clinical parameters.nnnCONCLUSIONnExogenous subclinical hyperthyroidism during adolescence has no demonstrable detrimental effect on peak bone mass attainment.
Journal of Pediatric Hematology Oncology | 2011
Suradej Hongeng; Chokdee Wongborisuth; Sinee Disthabanchong; Samart Pakakasama; Pat Mahachoklertwattana; Boonsong Ongphiphadhanakul; Surapol Issaragrisil; Rajata Rajatanavin
We compared osteoblast differentiation gene expressions in the isolated CD105+ mesenchymal stromal cells from bone marrow in 10 patients with severe thalassemia and 12 normal donor controls. The fold expressions of osteoblast differentiation genes of CD105+ cells from patients with thalassemia were lower than those of normal donors but increased after being cultured in Dulbeccos modified Eagles medium with 10% fetal calf serum. Moreover, the fold expressions of these genes of CD105+ cells from normal donors when cultured with 10% pooled serum of patients with thalassemia were lower than when cultured with 10% pooled serum of normal donors. We have also presented the evidence of reversible suppressed expression of these genes in CD105+cells from patients with thalassemia when cultured in pooled serum of normal donors. Moreover, healthy donor CD105+ cells exhibited lower expression of these genes when cultured in pooled serum of patients with thalassemia compared with pooled serum of normal donors indicating the existence of circulating factors in thalassemic serum impairing the differentiation of mesenchymal stromal cells to osteoblasts.
The Journal of Clinical Endocrinology and Metabolism | 2003
Pat Mahachoklertwattana; Vorachai Sirikulchayanonta; Ampaiwan Chuansumrit; Patcharee Karnsombat; Lulin Choubtum; Arporn Sriphrapradang; Somnuek Domrongkitchaiporn; Rojana Sirisriro; Rajata Rajatanavin
Journal of the Medical Association of Thailand Chotmaihet thangphaet | 2006
Suwannee Chanprasertyothin; Sunee Saetung; Penpan Payattikul; Rajata Rajatanavin; Boonsong Ongphiphadhanakul
Nephrology Dialysis Transplantation | 2004
Chatlert Pongchaiyakul; Somnuek Domrongkitchaiporn; Wasana Stitchantrakul; La-or Chailurkit; Rajata Rajatanavin
Endocrinology | 1989
Rajata Rajatanavin; Shieh-Lieh Fang; Sam Pino; Peter Laurberg; Lewis E. Braverman; Marsha Smith; Leslie P. Bullock
The Journal of Clinical Endocrinology and Metabolism | 1984
Rajata Rajatanavin; Ruth A. Young; Lewis E. Braverman
Endocrinology | 1986
Ruth A. Young; Rajata Rajatanavin; Lewis E. Braverman; Bud C. Tennant