Ralf Braun
Bayer
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Featured researches published by Ralf Braun.
RSC Advances | 2014
Camille Midrier; Sonia Montel; Ralf Braun; Klaus Haaf; Lothar Willms; Arie Van der Lee; Jean-Noël Volle; Jean-Luc Pirat; David Virieux
Fosmidomycin has been reported to have many biological activities as an antibacterial and antimalarial, along with being a herbicidal agent. Its unique mode of action involves the inhibition of a key step of the non mevalonate pathway by blockade of a crucial enzyme, the 1-deoxy-D-xylulose 5-phosphate reductoisomerase (DXR), whose expression is present in bacteria, plasmodium parasites and higher plants, but not in mammals. Herein we report the development of fosmidomycin and of FR-900098 constrained analogues belonging to an unusual heterocyclic based complexing subunit involving N-hydroxyimidazoles and cyclic N-hydroxyureas.
Archive | 2012
Ralf Braun; Simon Dörner-Rieping; Arnim Köhn; Hartmut Ahrens; Stefan Lehr; Andreas Van Almsick; Isolde Häuser-Hahn; Hansjörg Dietrich; Elmar Gatzweiler; Ines Heinemann; Christopher Hugh Rosinger
Archive | 2010
Arnim Köhn; Jörg Tiebes; Almsick Andreas Van; Hartmut Ahrens; Ines Heinemann; Ralf Braun; Monika Schmitt; Lothar Willms; Dieter Feucht; Christopher Hugh Rosinger; Isolde Häuser-Hahn; Mark Wilhelm Drewes; Simon Dörner-Rieping; Jan Dittgen; Martin Adamczewski
Archive | 2012
Arnim Köhn; Hartmut Ahrens; Ralf Braun; Simon Dörner-Rieping; Stefan Lehr; Ines Heinemann; Isolde Häuser-Hahn; Elmar Gatzweiler; Christopher Hugh Rosinger
Archive | 2011
Ralf Braun; Arnim Köhn; Andreas Van Almsick; Hartmut Ahrens; Simon Dörner-Rieping; Lothar Willms; Isolde Häuser-Hahn; Ines Heinemann; Elmar Gatzweiler; Christopher Hugh Rosinger
Archive | 2012
Armin Köhn; Stefan Lehr; Ralf Braun; Simon Dörner-Rieping; Hartmut Ahrens; Hansjörg Dietrich; Isolde Häuser-Hahn; Christopher Hugh Rosinger; Elmar Gatzweiler
European Journal of Organic Chemistry | 2012
Sonia Montel; Camille Midrier; Jean-Noël Volle; Ralf Braun; Klaus Haaf; Lothar Willms; Jean-Luc Pirat; David Virieux
Archive | 2010
Arnim Köhn; Jörg Tiebes; Andreas Van Almsick; Hartmut Ahrens; Ines Heinemann; Ralf Braun; Monika Schmitt; Lothar Willms; Dieter Feucht; Christopher Hugh Rosinger; Isolde Häuser-Hahn; Mark Wilhelm Drewes; Simon Dörner-Rieping; Jan Dittgen; Martin Adamczewski
Archive | 2012
Arnim Köhn; Almsick Andreas Van; Ralf Braun; Monika Schmitt; Jörg Tiebes; Ines Heinemann; Isolde Häuser-Hahn; Elmar Gatzweiler; Christopher Hugh Rosinger
Archive | 2004
Peter Jeschke; Michael Müller; Iris Escher; Olga Malsam; Karl-Josef Haack; Ralf Braun; Christian Arnold