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Dive into the research topics where Ram R. Chawla is active.

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Featured researches published by Ram R. Chawla.


Journal of Medicinal Chemistry | 1982

Species- or isozyme-specific enzyme inhibitors. 5. Differential effects of thymidine substituents on affinity for rat thymidine kinase isozymes.

Alexander Hampton; Ram R. Chawla


Journal of Medicinal Chemistry | 1984

Bis(m-nitrophenyl) and bis(p-nitrophenyl) esters and the phosphorodiamidate of thymidine 5'-phosphate as potential sources of intracellular thymidine 5'-phosphate in mouse cells in culture.

Ram R. Chawla; Jerome J. Freed; Alexander Hampton


Journal of Medicinal Chemistry | 1979

Design of species- or isozyme-specific enzyme inhibitors. 1. Effect of thymidine substituents on affinity for the thymidine site of hamster cytoplasmic thymidine kinase.

Alexander Hampton; Ram R. Chawla


Journal of Medicinal Chemistry | 1976

Evidence for species-specific substrate-site-directed inactivation of rabbit adenylate kinase by N6-(6-iodoacetamido-n-hexyl)adenosine 5'-triphosphate.

Alexander Hampton; Lewis A. Slotin; Ram R. Chawla


Journal of Medicinal Chemistry | 1986

Zwitterionic 3'-O-acyl derivatives of thymidine 5'-phosphate as potential sources of intracellular thymidine 5'-phosphate in cells in culture

Ram R. Chawla; Jerome J. Freed; Alexander Hampton


Journal of Medicinal Chemistry | 1982

Species- or isozyme-specific enzyme inhibitors. 6. Synthesis and evaluation of two-substrate condensation products as inhibitors of hexokinases and thymidine kinases.

Alexander Hampton; Ton T. Hai; Ram R. Chawla


ChemInform | 1982

SPECIES- AND ISOZYME-SPECIFIC ENZYME INHIBITORS. 6. SYNTHESIS AND EVALUATION OF TWO-SUBSTRATE CONDENSATION PRODUCTS AS INHIBITORS OF HEXOKINASES AND THYMIDINE KINASES

Alexander Hampton; Ton T. Hai; Ram R. Chawla


Journal of Medicinal Chemistry | 1979

Design of species- or isozyme-specific enzyme inhibitors. 2. Differences between a bacterial and a mammalian thymidine kinase in the effect of thymidine substituents on affinity for the thymidine site.

Alexander Hampton; Ram R. Chawla


Journal of Medicinal Chemistry | 1982

Use of adenine nucleotide derivatives to assess the potential of exo-active-site-directed reagents as species- or isozyme-specific enzyme inactivators. 5. Interactions of adenosine 5'-triphosphate derivatives with rat pyruvate kinases, Escherichia coli thymidine kinase, and yeast and rat hexokinases.

Alexander Hampton; Arvind D. Patel; Ram R. Chawla; Ton T. Hai


ChemInform | 1985

BIS(M-NITROPHENYL) AND BIS(P-NITROPHENYL) ESTERS AND THE PHOSPHORODIAMIDATE OF THYMIDINE 5′-PHOSPHATE AS POTENTIAL SOURCES OF INTRACELLULAR THYMIDINE 5′-PHOSPHATE IN MOUSE CELLS IN CULTURE

Ram R. Chawla; Jerome J. Freed; Alexander Hampton

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Ton T. Hai

Fox Chase Cancer Center

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