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Circulation | 2009

Heart Disease and Stroke Statistics—2009 Update A Report From the American Heart Association Statistics Committee and Stroke Statistics Subcommittee

Donald M. Lloyd-Jones; Robert Adams; Mercedes R. Carnethon; Giovanni de Simone; T. Bruce Ferguson; Katherine Flegal; Earl S. Ford; Karen L. Furie; Alan S. Go; Kurt J. Greenlund; Nancy Haase; Susan M. Hailpern; Michael Ho; Virginia J. Howard; Brett Kissela; Steven J. Kittner; Daniel T. Lackland; Lynda D. Lisabeth; Ariane J. Marelli; Mary M. McDermott; James B. Meigs; Dariush Mozaffarian; Graham Nichol; Christopher J. O'Donnell; Véronique L. Roger; Wayne Rosamond; Ralph L. Sacco; Paul D. Sorlie; Randall S. Stafford; Julia Steinberger

We thank Drs Robert Adams, Gary Friday, Philip Gorelick, and Sylvia Wasserthiel-Smoller, members of Stroke Statistics Subcommittee; Drs Joe Broderick, Brian Eigel, Kimberlee Gauveau, Jane Khoury, Jerry Potts, Jane Newburger, and Kathryn Taubert; and Sean Coady and Michael Wolz for their valuable comments and contributions. We acknowledge Tim Anderson and Tom Schneider for their editorial contributions and Karen Modesitt for her administrative assistance. View this table: Writing Group Disclosures # Summary {#article-title-2} Each year the American Heart Association, in conjunction with the Centers for Disease Control and Prevention, the National Institutes of Health, and other government agencies, brings together the most up-to-date statistics on heart disease, stroke, and their risk factors and presents them in its Heart Disease and Stroke Statistical Update. The Statistical Update is a valuable resource for researchers, clinicians, healthcare policy makers, media, the lay public, and many others who seek the …


Circulation | 2010

Heart Disease and Stroke Statistics—2010 Update A Report From the American Heart Association

Donald M. Lloyd-Jones; Robert J. Adams; Todd M. Brown; Mercedes R. Carnethon; Shifan Dai; Giovanni de Simone; T. Bruce Ferguson; Earl S. Ford; Karen L. Furie; Cathleen Gillespie; Alan S. Go; Kurt J. Greenlund; Nancy Haase; Susan M. Hailpern; P. Michael Ho; Virginia J. Howard; Brett Kissela; Steven J. Kittner; Daniel T. Lackland; Lynda D. Lisabeth; Ariane J. Marelli; Mary M. McDermott; James B. Meigs; Dariush Mozaffarian; Michael E. Mussolino; Graham Nichol; Véronique L. Roger; Wayne D. Rosamond; Ralph L. Sacco; Paul D. Sorlie

Appendix I: List of Statistical Fact Sheets. URL: http://www.americanheart.org/presenter.jhtml?identifier=2007 We wish to thank Drs Brian Eigel and Michael Wolz for their valuable comments and contributions. We would like to acknowledge Tim Anderson and Tom Schneider for their editorial contributions and Karen Modesitt for her administrative assistance. Disclosures View this table: View this table: View this table: # Summary {#article-title-2} Each year, the American Heart Association, in conjunction with the Centers for Disease Control and Prevention, the National Institutes of Health, and other government agencies, brings together the most up-to-date statistics on heart disease, stroke, other vascular diseases, and their risk factors and presents them in its Heart Disease and Stroke Statistical Update. The Statistical Update is a valuable resource for researchers, clinicians, healthcare policy makers, media professionals, the lay public, and many others who seek the best national data available on disease …


Circulation | 2011

Heart Disease and Stroke Statistics—2011 Update A Report From the American Heart Association

Véronique L. Roger; Alan S. Go; Donald M. Lloyd-Jones; Robert J. Adams; Jarett D. Berry; Todd M. Brown; Mercedes R. Carnethon; Shifan Dai; Giovanni de Simone; Earl S. Ford; Caroline S. Fox; Heather J. Fullerton; Cathleen Gillespie; Kurt J. Greenlund; Susan M. Hailpern; John A. Heit; P. Michael Ho; Virginia J. Howard; Brett Kissela; Steven J. Kittner; Daniel T. Lackland; Judith H. Lichtman; Lynda D. Lisabeth; Diane M. Makuc; Gregory M. Marcus; Ariane J. Marelli; David B. Matchar; Mary M. McDermott; James B. Meigs; Claudia S. Moy

Rosamond, Paul D. Sorlie, Randall S. Stafford, Tanya N. Turan, Melanie B. Turner, Nathan D. Dariush Mozaffarian, Michael E. Mussolino, Graham Nichol, Nina P. Paynter, Wayne D. Ariane Marelli, David B. Matchar, Mary M. McDermott, James B. Meigs, Claudia S. Moy, Lackland, Judith H. Lichtman, Lynda D. Lisabeth, Diane M. Makuc, Gregory M. Marcus, John A. Heit, P. Michael Ho, Virginia J. Howard, Brett M. Kissela, Steven J. Kittner, Daniel T. Caroline S. Fox, Heather J. Fullerton, Cathleen Gillespie, Kurt J. Greenlund, Susan M. Hailpern, Todd M. Brown, Mercedes R. Carnethon, Shifan Dai, Giovanni de Simone, Earl S. Ford, Véronique L. Roger, Alan S. Go, Donald M. Lloyd-Jones, Robert J. Adams, Jarett D. Berry, Association 2011 Update : A Report From the American Heart −− Heart Disease and Stroke Statistics


Circulation | 2010

Heart Disease and Stroke Statistics—2010 Update

Donald M. Lloyd-Jones; Robert J. Adams; Todd M. Brown; Mercedes R. Carnethon; Shifan Dai; Giovanni de Simone; T. Bruce Ferguson; Earl S. Ford; Karen L. Furie; Cathleen Gillespie; Alan S. Go; Kurt J. Greenlund; Nancy Haase; Susan M. Hailpern; P. Michael Ho; Virginia J. Howard; Brett Kissela; Steven J. Kittner; Daniel T. Lackland; Lynda D. Lisabeth; Ariane J. Marelli; Mary M. McDermott; James B. Meigs; Dariush Mozaffarian; Michael E. Mussolino; Graham Nichol; Véronique L. Roger; Wayne D. Rosamond; Ralph L. Sacco; Paul D. Sorlie

Appendix I: List of Statistical Fact Sheets. URL: http://www.americanheart.org/presenter.jhtml?identifier=2007 We wish to thank Drs Brian Eigel and Michael Wolz for their valuable comments and contributions. We would like to acknowledge Tim Anderson and Tom Schneider for their editorial contributions and Karen Modesitt for her administrative assistance. Disclosures View this table: View this table: View this table: # Summary {#article-title-2} Each year, the American Heart Association, in conjunction with the Centers for Disease Control and Prevention, the National Institutes of Health, and other government agencies, brings together the most up-to-date statistics on heart disease, stroke, other vascular diseases, and their risk factors and presents them in its Heart Disease and Stroke Statistical Update. The Statistical Update is a valuable resource for researchers, clinicians, healthcare policy makers, media professionals, the lay public, and many others who seek the best national data available on disease …


Circulation | 2009

Heart Disease and Stroke Statistics—2009 Update

Donald M. Lloyd-Jones; Robert J. Adams; Mercedes R. Carnethon; Giovanni de Simone; T. Bruce Ferguson; Katherine Flegal; Earl S. Ford; Karen L. Furie; Alan S. Go; Kurt J. Greenlund; Nancy Haase; Susan M. Hailpern; Michael Ho; Virginia J. Howard; Brett Kissela; Steven J. Kittner; Daniel T. Lackland; Lynda D. Lisabeth; Ariane J. Marelli; Mary M. McDermott; James B. Meigs; Dariush Mozaffarian; Graham Nichol; Christopher J. O'Donnell; Véronique L. Roger; Wayne D. Rosamond; Ralph L. Sacco; Paul D. Sorlie; Randall S. Stafford; Julia Steinberger

We thank Drs Sean Coady, Eric L. Ding, Brian Eigel, Gregg C. Fonarow, Linda Geiss, Cherie James, Michael Mussolino, and Michael Wolz for their valuable comments and contributions. We acknowledge Tim Anderson and Tom Schneider for their editorial contributions, and Karen Modesitt for her administrative assistance. Disclosures ⇓⇓⇓⇓ View this table: Writing Group Disclosures View this table: Writing Group Disclosures, Continued View this table: Writing Group Disclosures, Continued View this table: Writing Group Disclosures, Continued # Summary {#article-title-2} Each year, the American Heart Association, in conjunction with the Centers for Disease Control and Prevention, the National Institutes of Health, and other government agencies, brings together the most up-to-date statistics on heart disease, stroke, other vascular diseases, and their risk factors and presents them in its Heart Disease and Stroke Statistical Update. The Statistical Update is a valuable resource for researchers, clinicians, healthcare policy makers, media professionals, the lay …


Journal of the American College of Cardiology | 2003

The underutilization of cardiac medications of proven benefit, 1990 to 2002.

Randall S. Stafford; David C. Radley

OBJECTIVES To evaluate recent trends, we examined longitudinal national data on the outpatient use of warfarin in atrial fibrillation (AF), beta-blockers and aspirin in coronary artery disease (CAD), and angiotensin-converting enzyme inhibitors (ACEIs) in congestive heart failure (CHF). BACKGROUND Previous studies indicate that specific cardiac medications are underutilized. METHODS We used the National Disease and Therapeutic Index (NDTI) (produced by IMS HEALTH, Plymouth Meeting, Pennsylvania) for 1990 to 2002, and the National Ambulatory Medical Care Surveys (NAMCS) for 1990 to 2000 to follow nationally representative samples of outpatient visits. For visits by patients with AF (total n = 14,634 visits), CAD (n = 35,295), and CHF (n = 33,008), we examined trends in the proportion of visits with the selected medications reported. RESULTS Warfarin use in AF increased from 12% in 1990, to 41% in 1995, to 58% in 2001 in NDTI; a similar moderation of recent increase was seen in NAMCS. For CAD in NDTI, beta-blocker use increased slowly from 19% in 1990, to 20% in 1995, then to 40% in 2001; NAMCS showed this same pattern. Aspirin use in CAD in NDTI increased from 18% in 1990, to 19% in 1995, to 38% in 2001; NAMCS, however, showed lower use rates. For NDTI, ACEI use in CHF increased from 24% in 1990 to 36% in 1996, but increased to only 39% by 2001, a general pattern also seen in NAMCS. CONCLUSIONS Both national datasets demonstrate continuing underutilization of these cardiac medications of proven benefit. Although use is increasing, it remains lower than expected, and some increases noted in earlier years have slowed. Substantial public health benefits would result from further adoption of these effective therapies.


Pharmacoepidemiology and Drug Safety | 2011

INCREASING OFF-LABEL USE OF ANTIPSYCHOTIC MEDICATIONS IN THE UNITED STATES, 1995-2008

G.C. Alexander; S. A. Gallagher; A. Mascola; Rachael M. Moloney; Randall S. Stafford

To evaluate patterns of antipsychotic use.


Circulation | 1998

Recent National Patterns of Warfarin Use in Atrial Fibrillation

Randall S. Stafford; Daniel E. Singer

BACKGROUND Studies of selected populations suggest that anticoagulation in atrial fibrillation is underused and that nonclinical factors influence the use of this stroke-preventing therapy. We wished to examine recent national trends and predictors of warfarin sodium use in atrial fibrillation. METHODS AND RESULTS A nationally representative sample of office visits from the 1989 to 1996 National Ambulatory Medical Care Surveys was used. We selected 1125 visits by patients with atrial fibrillation, including 877 visits to cardiologists and primary care physicians in which apparent contraindications for anticoagulation were absent. The principal outcome measure was the proportion of visits with warfarin reported. We analyzed trends in warfarin use and statistically evaluated the predictors of warfarin use. Warfarin use increased from 13% of atrial fibrillation visits in 1989 to 40% in 1993 (P for trend <.001) in patients without contraindications. Between 1993 and 1996, however, there was no change in warfarin use. Independent of other factors, warfarin was significantly more likely to be reported in patients with a history of stroke and in patients residing outside of the South. CONCLUSIONS Warfarin use in atrial fibrillation has not increased recently, indicating inadequate implementation of this highly effective therapy. Barriers to anticoagulation in real-world clinical practice need to be identified and addressed.


The New England Journal of Medicine | 1989

Socioeconomic differences in rates of cesarean section.

Jeffrey B. Gould; Becky Davey; Randall S. Stafford

Abstract Increasing cesarean-section rates have focused attention on variations in the use of this procedure that appear to be independent of medical indication. We investigated the relation between the rate of primary cesarean section and socioeconomic status in a cohort of 245,854 singleton infants born to non-Hispanic white, black, Asian-American, and Mexican-American residents of Los Angeles County, California. On the basis of birth-certificate data for 1982 and 1983, a significant relation, independent of maternal age, parity, or birth weight, was found between the rates of primary cesarean section and socioeconomic status. Women who lived in census tracts with a median family income of more than


JAMA Internal Medicine | 2011

Electronic Health Records and Clinical Decision Support Systems Impact on National Ambulatory Care Quality

Max J. Romano; Randall S. Stafford

30,000 had a primary cesarean-section rate of 22.9 percent, as compared with 13.2 percent among women residing in areas with a median family income under

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Aaron C Logan

University of California

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