Rasa Tameliene
Lithuanian University of Health Sciences
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Featured researches published by Rasa Tameliene.
Acta Obstetricia et Gynecologica Scandinavica | 2008
Egle Barcaite; Arnoldas Bartusevičius; Rasa Tameliene; Mindaugas Kliucinskas; Laima Maleckiene; Ruta Nadisauskiene
Background. Group B streptococcus (GBS) is a leading cause of neonatal sepsis in many industrialised countries. However, the burden of perinatal GBS disease varies between these countries. We undertook a systematic review to determine the prevalence of maternal group B streptococcal colonisation, one of the most important risk factor for early onset neonatal infection, and to examine the serotype distribution of the GBS strains isolated and their susceptibility to antibiotics in European countries. Methods. We followed the standard methodology for systematic reviews. We prepared a protocol and a form for data extraction that identifies key characteristics on study and reporting quality. The search was conducted for the years 1996–2006 including electronic, hand searching and screening of reference lists. Results. Twenty‐one studies presented data on 24,093 women from 13 countries. Among all studies, GBS vaginal colonisation rates ranged from 6.5 to 36%, with one‐third of studies reporting rates of 20% or greater. The regional carriage rates were as follows: Eastern Europe 19.7–29.3%, Western Europe 11–21%, Scandinavia 24.3–36%, and Southern Europe 6.5–32%. GBS serotypes III, II and Ia were the most frequently identified serotypes. None of the GBS isolates were resistant to penicillin or ampicillin, whereas 3.8–21.2% showed resistance to erythromycin and 2.7–20% showed resistance to clindamycin. Conclusion. Although there is variation in the proportion of women colonised with GBS, the range of colonisation, the serotype distribution and antimicrobial susceptibility reported from European countries appears to be similar to that identified in overseas countries.
The Lancet Respiratory Medicine | 2015
Ricardo Carbajal; Mats Eriksson; Emilie Courtois; Elaine M. Boyle; Alejandro Avila-Alvarez; Randi Dovland Andersen; Kosmas Sarafidis; Tarja Pölkki; C. Matos; Paola Lago; T. Papadouri; Simon Attard Montalto; Mari-Liis Ilmoja; Sinno Simons; Rasa Tameliene; Bart Van Overmeire; Angelika Berger; Anna Dobrzanska; Michael Schroth; Lena Bergqvist; Hugo Lagercrantz; K.J.S. Anand
BACKGROUND Neonates who are in pain or are stressed during care in the intensive care unit (ICU) are often given sedation or analgesia. We investigated the current use of sedation or analgesia in neonatal ICUs (NICUs) in European countries. METHODS EUROPAIN (EUROpean Pain Audit In Neonates) was a prospective cohort study of the management of sedation and analgesia in patients in NICUs. All neonates admitted to NICUs during 1 month were included in this study. Data on demographics, methods of respiration, use of continuous or intermittent sedation, analgesia, or neuromuscular blockers, pain assessments, and drug withdrawal syndromes were gathered during the first 28 days of admission to NICUs. Multivariable linear regression models and propensity scores were used to assess the association between duration of tracheal ventilation (TV) and exposure to opioids, sedatives-hypnotics, or general anaesthetics in neonates (O-SH-GA). This study is registered with ClinicalTrials.gov, number NCT01694745. FINDINGS From Oct 1, 2012, to June 30, 2013, 6680 neonates were enrolled in 243 NICUs in 18 European countries. Mean gestational age of these neonates was 35.0 weeks (SD 4.6) and birthweight was 2384 g (1007). 2142 (32%) neonates were given TV, 1496 (22%) non-invasive ventilation (NIV), and 3042 (46%) were kept on spontaneous ventilation (SV). 1746 (82%), 266 (18%), and 282 (9%) neonates in the TV, NIV, and SV groups, respectively, were given sedation or analgesia as a continuous infusion, intermittent doses, or both (p<0.0001). In the participating NICUs, the median use of sedation or analgesia was 89.3% (70.0-100) for neonates in the TV group. Opioids were given to 1764 (26%) of 6680 neonates and to 1589 (74%) of 2142 neonates in the TV group. Midazolam was given to 576 (9%) of 6680 neonates and 536 (25%) neonates of 2142 neonates in the TV group. 542 (25%) neonates in the TV group were given neuromuscular blockers, which were administered as continuous infusions to 146 (7%) of these neonates. Pain assessments were recorded in 1250 (58%) of 2138, 672 (45%) of 1493, and 916 (30%) of 3017 neonates in the TV, NIV, and SV groups, respectively (p<0.0001). In the univariate analysis, neonates given O-SH-GA in the TV group needed a longer duration of TV than did those who were not given O-SH-GA (mean 136.2 h [SD 173.1] vs 39.8 h [94.7] h; p<0.0001). Multivariable and propensity score analyses confirmed this association (p<0.0001). INTERPRETATION Wide variations in sedation and analgesia practices occur between NICUs and countries. Widespread use of O-SH-GA in intubated neonates might prolong their need for mechanical ventilation, but further research is needed to investigate the therapeutic and adverse effects of O-SH-GA in neonates, and to develop new and safe approaches for sedation and analgesia. FUNDING European Communitys Seventh Framework Programme.
Acta Paediatrica | 2017
K.J.S. Anand; Mats Eriksson; Elaine M. Boyle; Alejandro Avila-Alvarez; Randi Dovland Andersen; Kosmas Sarafidis; Tarja Pölkki; C. Matos; Paola Lago; T. Papadouri; Simon Attard-Montalto; Mari-Liis Ilmoja; Sinno Simons; Rasa Tameliene; Bart Van Overmeire; Angelika Berger; Anna Dobrzanska; Michael Schroth; Lena Bergqvist; Emilie Courtois; Jessica Rousseau; Ricardo Carbajal
Continuous pain occurs routinely, even after invasive procedures, or inflammation and surgery, but clinical practices associated with assessments of continuous pain remain unknown.
International Journal of Gynecology & Obstetrics | 2012
Egle Barcaite; Arnoldas Bartusevičius; Rasa Tameliene; Laima Maleckiene; Astra Vitkauskiene; Ruta Nadisauskiene
To evaluate the prevalence of maternal and neonatal colonization with group B streptococcus (GBS) and Escherichia coli, and examine GBS serotypes and susceptibility to antibiotics.
Archives of Disease in Childhood | 2014
Ricardo Carbajal; Mats Eriksson; Emilie Courtois; Alejandro Avila-Alvarez; Angelika Berger; Paola Lago; Bart Van Overmeire; T. Papadouri; Mari-Liis Ilmoja; Tarja Pölkki; Michael Schroth; Kosmas Sarafidis; Rasa Tameliene; S. Attard Montalto; Sinno Simons; Randi Dovland Andersen; Anna Dobrzanska; C. Matos; Elaine M. Boyle; Hugo Lagercrantz; Lena Bergqvist; Kjs Anand
Background Pain and stress induced by mechanical ventilation, invasive procedures, or painful diseases supports the use of sedation/analgesia (S/A) in newborns admitted to Neonatal Intensive Care Units (NICUs). To date, these practices have not been studied at a large scale. Objective To determine current clinical practices regarding the use of S/A drugs in NICUs across Europe. Methods This epidemiological observational study on bedside clinical practices regarding S/A collected data for all neonates in participating NICUs until the infant left the unit (discharge, death, transfer) or for up to 28 days. Data collection occurred via an online database for 1 month at each NICU. All neonates up to 44 weeks gestation were included. Results From October 2012 to June 2013, 243 NICUs from 18 European countries collected data on 6680 eligible neonates. Of these, 2142 received tracheal ventilation (TV), 1496 non-invasive ventilation (NIV) and 3042 only spontaneous ventilation (SV). The median (IQR) gestational age of TV, NIV and SV neonates were 32.1 (28.1–37.4), 33.6 (31.0–36.6) and 37.9 (35.0–39.9), respectively (p < 0.001). Overall, more TV neonates [81.5% (n = 1746)] received S/A drugs than NIV neonates [17.8% (n = 266)] and SV neonates [9.3% (n = 282)]; p < 0.001. Fig. shows the rate of S/A use by country; table shows S/A drugs used. Abstract O-103 Table 1 Sedation/analgesia drugs used in TV, NIV and SV neonates neonates Abstract O-103 Figure 1 Rate of Analgesia/sedation in 2142 tracheal ventilated neonates (TV) and 1496 Non invasive ventilated neonates (NIV) admitted to NIUC in 18 European countries Conclusions Most ventilated but few non-ventilated neonates (NIV and SV) receive S/A therapy in European NICUs. Wide variations in S/A use, drugs used, and mode of administration (continuous, bolus, or both) exist among countries.
Journal of Maternal-fetal & Neonatal Medicine | 2018
Janina Ribeliene; Aurelija Blazeviciene; Ruta Nadisauskiene; Rasa Tameliene; Ausrele Kudreviciene; Irena Nedzelskiene; Jurate Macijauskiene
Abstract Background: Patients treated in health care facilities that provide services in the fields of obstetrics, gynecology, and neonatology are especially vulnerable. Large multidisciplinary teams of physicians, multiple invasive and noninvasive diagnostic and therapeutic procedures, and the use of advanced technologies increase the probability of adverse events. The evaluation of knowledge about patient safety culture among nurses and midwives working in such units and the identification of critical areas at a health care institution would reduce the number of adverse events and improve patient safety. The aim of the study was to evaluate the opinion of nurses and midwives working in clinical departments that provide services in the fields of obstetrics, gynecology, and neonatology about patient safety culture and to explore potential predictors for the overall perception of safety. Methods: We used the Hospital Survey on Patient Safety Culture (HSOPSC) to evaluate nurses’ and midwives’ opinion about patient safety issues. The overall response rate in the survey was 100% (n = 233). Results: The analysis of the dimensions of safety on the unit level showed that the respondents’ most positive evaluations were in the Organizational Learning – Continuous Improvement (73.2%) and Feedback and Communication about Error (66.8%) dimensions, and the most negative evaluations in the Non-punitive Response to Error (33.5%) and Staffing (44.6%) dimensions. On the hospital level, the evaluation of the safety dimensions ranged between 41.4 and 56.8%. The percentage of positive responses in the outcome dimensions Frequency of Events Reported was 82.4%. We found a significant association between the outcome dimension Frequency of Events Reported and the Hospital Management Support for Patient Safety and Feedback and Communication about Error Dimensions. Conclusions: On the hospital level, the critical domains in health care facilities that provide services in the fields of obstetrics, gynecology, and neonatology were Teamwork Across Hospital Units, and on the unit level – Communication Openness, Teamwork Within Units, Non-punitive Response to Error, and Staffing. The remaining domains were seen as having a potential for improvement.
Journal of Maternal-fetal & Neonatal Medicine | 2017
Ausrele Kudreviciene; Ruta Nadisauskiene; Rasa Tameliene; Algimantas Tamelis; Irena Nedzelskiene; Paulius Dobozinskas; Dinas Vaitkaitis
Abstract Background: Ensuring long-term retention of the acquired practical skills is one of the major aims of a medical school. This depends on the application of training techniques and their combinations. In order to standardize the teaching process, to acquire and maintain a broad array of technical, professional, and interpersonal skills and competencies, and to improve the retention of practical skills, we developed a new training technique – the HybridLab® learning method. It consists of an e-learning platform, hands-on simulation, carefully elaborated learning algorithms (DRAKON), peer-to-peer teaching, and assessment and feedback by peers, and later – by a remote instructor. Summary of the work: The subjects of the study were fifth-year students of the Lithuanian University of Health Sciences Medical Academy who during 2014–2015 were studying the obstetrics and gynecology module in the neonatology cycle. We analyzed the retention of practical skills in the initial neonatal resuscitation among students who were training with the use of our developed HybridLab® technique at 6 and 12 months after the completion of the cycle. Summary of results: After 6 and 12 months, mean changes in the subjects’ evaluation scores (percentage drop-off between the first and the second total score) dropped by, respectively, 31.8% (SD: 27.5) and 7.7% (SD: 25.6), and did not differ statistically significantly (p = .2). In the group of subjects who were not given a possibility to remember the skills and the course of initial neonatal resuscitation, the mean change between the first and the second total evaluation scores was 42.5% (SD: 26.7). In students who were given such possibility, the mean change between the first and the second total evaluation scores was significantly smaller −12.7% (SD: 13.8) (p < .001). Changes in the evaluation scores of individual skills (first steps, mouth-to-mouth ventilation, and chest compressions) between the first and the second evaluation also differed statistically significantly and were smaller in the group of students who were given a possibility to remember their skills (p < .001). Discussion: The HybridLab® learning method is a novel technique, and thus more studies are required to evaluate the significance of the HybridLab® technique for long-time retention of practical skills. Conclusion: As a result of the application of the HybridLab® training technique, practical skill retention among medical students after 6 and 12 months dropped by only about 13%. A recall system significantly improved practical skill retention.
Clinical Pediatrics | 2016
Vesta Kucinskiene; Laura Russetti; Dalia Stoniene; Astra Vitkauskiene; Skaidra Valiukeviciene; Rasa Tameliene
Congenital syphilis is usually diagnosed at an early stage by using epidemiological, objective, and the mother’s and the newborn’s serological criteria. As only laboratory criteria can confirm a case of congenital syphilis, specialists do not pay much attention to the clinical symptoms of this congenital infection, especially when these symptoms are nonspecific. The aim of our case report is to review the clinical symptoms of congenital syphilis and to survey the clinical variations of the published cases of congenital syphilis over the past 5 years.
MedEdPublish | 2016
Ausrele Kudreviciene; Ruta Nadisauskiene; Rasa Tameliene; Jurgita Garcinskiene; Irena Nedzelskiene; Algimantas Tamelis; Paulius Dobozinskas; Dinas Vaitkaitis
Resuscitation | 2015
Ausrele Kudreviciene; Algidas Basevičius; Saulius Lukoševičius; Jurate Laurynaitiene; Vitalija Marmiene; Irena Nedzelskiene; Rasa Tameliene