Raymond A. Mar

The common neural basis of autobiographical memory, prospection, navigation, theory of mind, and the default mode: A quantitative meta-analysis

A core brain network has been proposed to underlie a number of different processes, including remembering, prospection, navigation, and theory of mind [Buckner, R. L., & Carroll, D. C. Self-projection and the brain. Trends in Cognitive Sciences, 11, 49–57, 2007]. This purported network—medial prefrontal, medial-temporal, and medial and lateral parietal regions—is similar to that observed during default-mode processing and has been argued to represent self-projection [Buckner, R. L., & Carroll, D. C. Self-projection and the brain. Trends in Cognitive Sciences, 11, 49–57, 2007] or scene-construction [Hassabis, D., & Maguire, E. A. Deconstructing episodic memory with construction. Trends in Cognitive Sciences, 11, 299–306, 2007]. To date, no systematic and quantitative demonstration of evidence for this common network has been presented. Using the activation likelihood estimation (ALE) approach, we conducted four separate quantitative meta-analyses of neuroimaging studies on: (a) autobiographical memory, (b) navigation, (c) theory of mind, and (d) default mode. A conjunction analysis between these domains demonstrated a high degree of correspondence. We compared these findings to a separate ALE analysis of prospection studies and found additional correspondence. Across all domains, and consistent with the proposed network, correspondence was found within the medial-temporal lobe, precuneus, posterior cingulate, retrosplenial cortex, and the temporo-parietal junction. Additionally, this study revealed that the core network extends to lateral prefrontal and occipital cortices. Autobiographical memory, prospection, theory of mind, and default mode demonstrated further reliable involvement of the medial prefrontal cortex and lateral temporal cortices. Autobiographical memory and theory of mind, previously studied as distinct, exhibited extensive functional overlap. These findings represent quantitative evidence for a core network underlying a variety of cognitive domains.

The Neural Bases of Social Cognition and Story Comprehension

A great deal of research exists on the neural basis of theory-of-mind (ToM) or mentalizing. Qualitative reviews on this topic have identified a mentalizing network composed of the medial prefrontal cortex, posterior cingulate/precuneus, and bilateral temporal parietal junction. These conclusions, however, are not based on a quantitative and systematic approach. The current review presents a quantitative meta-analysis of neuroimaging studies pertaining to ToM, using the activation-likelihood estimation (ALE) approach. Separate ALE meta-analyses are presented for story-based and nonstory-based studies of ToM. The conjunction of these two meta-analyses reveals a core mentalizing network that includes areas not typically noted by previous reviews. A third ALE meta-analysis was conducted with respect to story comprehension in order to examine the relation between ToM and stories. Story processing overlapped with many regions of the core mentalizing network, and these shared regions bear some resemblance to a network implicated by a number of other processes.

The Function of Fiction is the Abstraction and Simulation of Social Experience.

Fiction literature has largely been ignored by psychology researchers because its only function seems to be entertainment, with no connection to empirical validity. We argue that literary narratives have a more important purpose. They offer models or simulations of the social world via abstraction, simplification, and compression. Narrative fiction also creates a deep and immersive simulative experience of social interactions for readers. This simulation facilitates the communication and understanding of social information and makes it more compelling, achieving a form of learning through experience. Engaging in the simulative experiences of fiction literature can facilitate the understanding of others who are different from ourselves and can augment our capacity for empathy and social inference.

The Toronto Empathy Questionnaire: Scale development and initial validation of a factor-analytic solution to multiple empathy measures

To formulate a parsimonious tool to assess empathy, we used factor analysis on a combination of self-report measures to examine consensus and developed a brief self-report measure of this common factor. The Toronto Empathy Questionnaire (TEQ) represents empathy as a primarily emotional process. In 3 studies, the TEQ demonstrated strong convergent validity, correlating positively with behavioral measures of social decoding, self-report measures of empathy, and negatively with a measure of Autism symptomatology. Moreover, it exhibited good internal consistency and high test–retest reliability. The TEQ is a brief, reliable, and valid instrument for the assessment of empathy.

Psychological Entropy: A Framework for Understanding Uncertainty-Related Anxiety

Entropy, a concept derived from thermodynamics and information theory, describes the amount of uncertainty and disorder within a system. Self-organizing systems engage in a continual dialogue with the environment and must adapt themselves to changing circumstances to keep internal entropy at a manageable level. We propose the entropy model of uncertainty (EMU), an integrative theoretical framework that applies the idea of entropy to the human information system to understand uncertainty-related anxiety. Four major tenets of EMU are proposed: (a) Uncertainty poses a critical adaptive challenge for any organism, so individuals are motivated to keep it at a manageable level; (b) uncertainty emerges as a function of the conflict between competing perceptual and behavioral affordances; (c) adopting clear goals and belief structures helps to constrain the experience of uncertainty by reducing the spread of competing affordances; and (d) uncertainty is experienced subjectively as anxiety and is associated with activity in the anterior cingulate cortex and with heightened noradrenaline release. By placing the discussion of uncertainty management, a fundamental biological necessity, within the framework of information theory and self-organizing systems, our model helps to situate key psychological processes within a broader physical, conceptual, and evolutionary context.

Exploring the link between reading fiction and empathy: Ruling out individual differences and examining outcomes

Abstract Readers of fiction tend to have better abilities of empathy and theory of mind (Mar et al., Journal of Personality 74: 1047–1078, 2006). We present a study designed to replicate this finding, rule out one possible explanation, and extend the assessment of social outcomes. In order to rule out the role of personality, we first identified Openness as the most consistent correlate. This trait was then statistically controlled for, along with two other important individual differences: the tendency to be drawn into stories and gender. Even after accounting for these variables, fiction exposure still predicted performance on an empathy task. Extending these results, we also found that exposure to fiction was positively correlated with social support. Exposure to nonfiction, in contrast, was associated with loneliness, and negatively related to social support.

Emotion and narrative fiction: Interactive influences before, during, and after reading

Emotions are central to the experience of literary narrative fiction. Affect and mood can influence what book people choose, based partly on whether their goal is to change or maintain their current emotional state. Once having chosen a book, the narrative itself acts to evoke and transform emotions, both directly through the events and characters depicted and through the cueing of emotionally valenced memories. Once evoked by the story, these emotions can in turn influence a persons experience of the narrative. Lastly, emotions experienced during reading may have consequences after closing the covers of a book. This article reviews the current state of empirical research for each of these stages, providing a snapshot of what is known about the interaction between emotions and literary narrative fiction. With this, we can begin to sketch the outlines of what remains to be discovered.

I remember you: A role for memory in social cognition and the functional neuroanatomy of their interaction

Remembering events from the personal past (autobiographical memory) and inferring the thoughts and feelings of other people (mentalizing) share a neural substrate. The shared functional neuroanatomy of these processes has been demonstrated in a meta-analysis of independent task domains (Spreng, Mar & Kim, 2009) and within subjects performing both tasks (Rabin, Gilboa, Stuss, Mar, & Rosenbaum, 2010; Spreng & Grady, 2010). Here, we examine spontaneous low-frequency fluctuations in fMRI BOLD signal during rest from two separate regions key to memory and mentalizing, the left hippocampus and right temporal parietal junction, respectively. Activity in these two regions was then correlated with the entire brain in a resting-state functional connectivity analysis. Although the left hippocampus and right temporal parietal junction were not correlated with each other, both were correlated with a distributed network of brain regions. These regions were consistent with the previously observed overlap between autobiographical memory and mentalizing evoked brain activity found in past studies. Reliable patterns of overlap included the superior temporal sulcus, anterior temporal lobe, lateral inferior parietal cortex (angular gyrus), posterior cingulate cortex, dorsomedial and ventral prefrontal cortex, inferior frontal gyrus, and the amygdala. We propose that the functional overlap facilitates the integration of personal and interpersonal information and provides a means for personal experiences to become social conceptual knowledge. This knowledge, in turn, informs strategic social behavior in support of personal goals. In closing, we argue for a new perspective within social cognitive neuroscience, emphasizing the importance of memory in social cognition.

Lost in localization: The need for a universal coordinate database

One of the great advantages of neuroimaging research is the use of an established and uniform coordinate system. This 3-D coordinate system allows for the comparison of activation locations across studies. In order to capitalize upon this advantage, however, researchers must be able to find relevant studies based upon activation locations. A number of research groups have embarked upon solutions to this problem, but to date there exists no exhaustive, universal coordinate database. In this commentary we outline the nature of the problem, its current solutions, and propose alternate solutions. We close with suggestions on how those in the field can facilitate the process of developing a universal coordinate database.

The hierarchical structure of childhood personality in five countries: continuity from early childhood to early adolescence.

Childhood personality is a rapidly growing area of investigation within individual differences research. One understudied topic is the universality of the hierarchical structure of childhood personality. In the present investigation, parents rated the personality characteristics of 3,751 children from 5 countries and 4 age groups. The hierarchical structure of childhood personality was examined for 1-, 2-, 3-, 4-, and 5-factor models across country (Canada, China, Greece, Russia, and the United States) and age group (3-5, 6-8, 9-11, and 12-14 years of age). Many similarities were noted across both country and age. The Five-Factor Model was salient beginning in early childhood (ages 3-5). Deviations across groups and from adult findings are noted, including the prominent role of antagonism in childhood personality and the high covariation between Conscientiousness and intellect. Future directions, including the need for more explicit attempts to merge temperament and personality models, are discussed.