Raymond H. Colton

Dysphonia in the aging: physiology versus disease.

A chart review from 151 dysphonic patients over the age of 60 was done to define aging related voice disorders. Overwhelmingly, patients suffered from dysphonia due to disease processes associated with aging rather than to physiologic aging alone. These include: 1. central neurological disorders affecting laryngeal function (e.g., stroke, Parkinsons disease, essential tremor, Alzheimers disease); 2. benign vocal fold lesions (e.g., Reinkes edema, benign and dysplastic epithelial lesions); 3. inflammatory disorders (e.g., laryngitis sicca, medication effect); 4. laryngeal neoplasia; and 5. laryngeal paralysis. Typical laryngeal findings of vocal fold bowing and breathiness consistent with presbylarynges were present in only six patients. Presbylarynges is not a common disorder and should be a diagnosis of exclusion made only after careful medical and speech evaluation.

Diagnosis and treatment of persistent dysphonia after laryngeal surgery: A retrospective analysis of 62 patients

Sixty‐two patients with persistent or recurrent dysphonia after laryngeal surgery underwent interdisciplinary voice evaluation, laryngostroboscopy, and objective measurements of vocal function. The causes of persistent dysphonia were attributed to vocal fold scarring (n = 22), residual mass lesion (n = 8), residual inflammation (n = 13), recurrent mass (n = 4), and hyperfunctional voice disorder (n = 7). Laryngoscopy often showed excessive ventricular compression and anterior‐to‐posterior laryngeal compression. Ventricular dysphonia was often a compensatory gesture in response to poorly mobile vocal fold membranes. Stroboscopy was able to document a number of abnormalities which included abnormalities of laryngeal configuration, vibratory asymmetry, reduction of amplitude, and mucosal wave. Using a diversified approach consisting of medical therapy, voice therapy, and repeat surgery, better vocal function was able to be restored in the majority of patients. An interdisciplinary approach to the dysphonic patient after laryngeal surgery was most useful in defining the pathology and refining a treatment rehabilitation program.

Spectral- and Cepstral-Based Measures During Continuous Speech: Capacity to Distinguish Dysphonia and Consistency Within a Speaker

Spectral- and cepstral-based acoustic measures are preferable to time-based measures for accurately representing dysphonic voices during continuous speech. Although these measures show promising relationships to perceptual voice quality ratings, less is known regarding their ability to differentiate normal from dysphonic voice during continuous speech and the consistency of these measures across multiple utterances by the same speaker. The purpose of this study was to determine whether spectral moments of the long-term average spectrum (LTAS) (spectral mean, standard deviation, skewness, and kurtosis) and cepstral peak prominence measures were significantly different for speakers with and without voice disorders when assessed during continuous speech. The consistency of these measures within a speaker across utterances was also addressed. Continuous speech samples from 27 subjects without voice disorders and 27 subjects with mixed voice disorders were acoustically analyzed. In addition, voice samples were perceptually rated for overall severity. Acoustic analyses were performed on three continuous speech stimuli from a reading passage: two full sentences and one constituent phrase. Significant between-group differences were found for both cepstral measures and three LTAS measures (P<0.001): spectral mean, skewness, and kurtosis. These five measures also showed moderate to strong correlations to overall voice severity. Furthermore, high degrees of within-speaker consistency (correlation coefficients ≥0.89) across utterances with varying length and phonemic content were evidenced for both subject groups.

Position of the hyoid and larynx in people with muscle tension dysphonia

To determine whether radiographic measures of hyoid position, laryngeal position, and hyolaryngeal space during phonation were different for people with primary muscle tension dysphonia (MTD) as compared to control participants without voice disorders.

Spectral- and cepstral-based acoustic features of dysphonic, strained voice quality

Objectives We sought to determine whether spectral- and cepstral-based acoustic measures were effective in distinguishing dysphonic-strained voice quality from normal voice quality and whether these measures were related to auditory-perceptual ratings of strain severity. Methods Voice samples from 23 speakers with dysphonia characterized predominantly by strained voice quality and 23 speakers with normal voice were acoustically analyzed. Measures related to the prominence of the cepstral peak and the ratio of low- to high-frequency spectral energies, as well as the variation of each, were computed from continuous speech and a sustained vowel. Correlations to perceptually rated strain severity were determined. Results Measures related to the cepstrum were the strongest discriminators between dysphonic-strained voice and normal voice. Variation in the ratio of low- to high-frequency spectral energies also significantly differentiated the two speaker groups. All measures were significantly correlated with perceptually rated strain severity, including an acoustic severity index that incorporated both cepstral- and spectral-based measures. Conclusions Cepstral- and spectral-based measures that have been previously studied in dysphonia characterized by breathiness and roughness are effective in distinguishing strained dysphonia from normal voice quality. The utility of these acoustic measures is supported by their moderate-to-high relationship with perceptually rated strain severity.

Elements of Voice Quality: Perceptual, Acoustic, and Physiologic Aspects

Publisher Summary This chapter discusses the elements of voice quality and its perceptual, acoustic, and physiologic aspects. Voice quality has been of great interest to many professions concerned with the voice from those in medicine who listen to pathologic voices to those in music who must develop professional voices. Research in voice quality has been abundant, varied, and very often disparate. Phonetically, voice quality changes with each change in vowel. A person makes these quality changes thousands of times a day as he shifts from vowel to vowel to consonant. These phonetic changes are made by most speakers using what may be viewed as a habitual set of the articulators. There are temporary physiologic conditions, such as pain, fatigue, excitement, cold, illness, or physical strain that can effect changes in voice quality. In addition to these unconscious forces that may impose a characteristic color, there are also conscious ways of using voice that may be calculated to soothe, to excite, to control, or to conform. Nevertheless, with all the possible variations, there are some similarities and dissimilarities among all voice qualities

Aerodynamic and Acoustic Features of Vocal Effort

OBJECTIVES The purpose of this study was to determine the aerodynamic and acoustic features of speech produced at comfortable, maximal and minimal levels of vocal effort. STUDY DESIGN Prospective, quasi-experimental research design. METHOD Eighteen healthy participants with normal voice were included in this study. After task training, participants produced repeated syllable combinations at comfortable, maximal and minimal levels of vocal effort. A pneumotachometer and vented (Rothenberg) mask were used to record aerodynamic data, with simultaneous recording of the acoustic signal for subsequent analysis. Aerodynamic measures of subglottal pressure, translaryngeal airflow, maximum flow declination rate (MFDR), and laryngeal resistance were analyzed, along with acoustic measures of cepstral peak prominence (CPP) and its standard deviation (SD). RESULTS Participants produced significantly greater subglottal pressure, translaryngeal airflow, and MFDR during maximal effort speech as compared with comfortable vocal effort. When producing speech at minimal vocal effort, participants lowered subglottal pressure, MFDR, and laryngeal resistance. Acoustic changes associated with changes in vocal effort included significantly higher CPP during maximal effort speech and significantly lower CPP SD during minimal effort speech, when each was compared with comfortable effort. CONCLUSIONS For healthy speakers without voice disorders, subglottal pressure, translaryngeal airflow, and MFDR may be important factors that contribute to an increased sense of vocal effort. Changes in the cepstral signal also occur under conditions of increased or decreased vocal effort relative to comfortable effort.

Phonatory airflow analysis in patients with laryngeal disease.

Phonatory airflow was recorded in 150 patients with various laryngeal diseases and in 60 persons with normal voices. All subjects produced several sustained vowels at different loudness levels. Disturbances of voice due to laryngeal disease may be manifested as variations of mean flow (DC), alternating flow (AC), or as a variation in the amplitude of the frequency components of the airflow signal (frequency spectra). The quantification of airflow characteristics is important if the clinician is to have a better understanding of laryngeal disease. Furthermore, preoperative and postoperative analysis can serve to document therapeutic effectiveness.

Spectral Moment Analysis of Unilateral Vocal Fold Paralysis

Many acoustic measures have been used to assess and track the voices of patients with voice problems. Some of these measures rely on the accurate measurement of fundamental frequency to produce reliable results. Patients with voice disorders often produce voices with considerable quasiperiodicity or aperiodicity. There are other measurements that do not depend on the accurate tracking of fundamental frequency by computing the spectrum of the sound and comparing different parts of the spectrum. The moments of the spectral distribution may also be important measurements to use in patients with voice problems. Several studies have reported good results using these measures to track treatment progress. In this study, spectral moments were used to assess the effectiveness of two treatment approaches in patients with unilateral vocal fold paralysis (UVFP). Twenty-six patients with UVFP and dysphonia (16 female and 10 male patients) were studied. Thirteen underwent surgery to improve their voice, whereas the other 13 received voice therapy. The patients were recorded at three time intervals: before the start of treatment, about 1 month after treatment has been completed, and at 3 months after treatment. They produced three types of speech material, vowels /ah/ and /oo/ and a simple sentence. The first four spectral moments (mean, standard deviation, skewness, and kurtosis) were computed from the long-term average spectrum. Severity of voice dysphonia was rated on a 11-point scale ranging from 0 (normal) to 10 (aphonic). There were no statistical differences between males and females for any of the four moments. There was also no difference between the two treatment types. There were differences among the three types of speech material for moments 1 and 3. There were also differences for moments 1, 2, and 3 for the three treatment conditions with most of the differences occurring between the pretreatment and first posttreatment condition. Severity of dysphonia decreased significantly from the pretreatment to either of the two posttreatment conditions. Spectral moments appear to be viable acoustic measurements to use to assess the effects of treatment on the voice of patients with UVFP.

The effect of tracheostomy on posterior cricoarytenoid muscle

It has been reported previously that the amount of electromyographic (EMG) potential of the posterior cricoarytenoid (PCA) decreases after prolonged tracheostomy. It is, therefore, reasonable to assume that a significant alteration of the biochemical characteristics of this muscle would also occur. In addition to histochemical analysis, endoscopic and EMG data were recorded to give a direct comparison in each subject. Seven male beagles were used for this study. Four were tracheostomized and three served as controls. They were examined immediately before and after surgery and again after 4 weeks by EMG and endoscopic techniques. Histochemical staining was performed on each subject. All three modalities failed to demonstrate a substantial difference between the controls and the experimental dogs.