Raymundo Martins Castro

The treatment of Brazilian pemphigus foliaceus (fogo selvagem).

Brazilian pemphigus foliaceus (fogo selvagem) occurs endemically in the central-southern states, especially in the areas that are still being settled. Before corticoids were introduced into the treatment of this dermatosis, prognosis was poor. Tlie ailment took either an acute or chronic form, frequently being fatal. In some exceptional cases the ailment subsided spontaneously. With the goal of studying therapeutic results as well as side ellects of corticoid therapy for this condition, a work group was formed that carried out therapeutic tests with thiee corticoids in four diflerent centers: Sao Paulo (SP) Goiania (CO), Belo Horizonte (MG) and Rio de Janeiro (GB). Experiments were carried out simultaneously and the participants Iield regular meetings during this twelve-month period.

Histoplasmose cutâneo-mucosa: relato de dois casos em irmãos

Two cases of muco-cutaneous histoplasmosis in brothers are presented. The first case under specific treatment improved, quickly but had recidive with lecions in the nervous system, three years afterwards, leading to death. In the second cave, the diagnosis was performed earlier and under specific treatment clinical cure ocurred. The pacient is still under clinical control. In both cases, the clinical aspects of muco-cutaneous ristoplasmosis were similar to those of South American blastomycosis (paracoccidicdcmycosis). The firts diagnosis was post-mortem and the second one was by fungus isolation, in culture, and the presence of the Histoplasma capsulatum in the histological sections.